Effect of aqueous extract of Allium saralicum R.M. Fritsch on fatty liver induced by high-fat diet in Wistar rats

2018 ◽  
Vol 28 (5) ◽  
pp. 1205-1211 ◽  
Author(s):  
Rohallah Moradi ◽  
Majid Hajialiani ◽  
Saman Salmani ◽  
Maryam Almasi ◽  
Akram Zangeneh ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat

Histopathological and biochemical effects of aqueous extract of Tragopogon graminifolius on the liver tissues of Wistar rats fed with high-fat diet

2018 ◽  
Vol 28 (5) ◽  
pp. 1197-1203 ◽  
Author(s):  
Mohammad Mahdi Zangeneh ◽  
Saman Salmani ◽  
Akram Zangeneh ◽  
Reza Khedri ◽  
Mohammad Saeid Zarei
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Biochemical Effects ◽  
Tragopogon Graminifolius ◽  
Liver Tissues

scholarly journals Ameliorative Effects of Aqueous Extract of Date Palm Fruits (phoenix dactylifera) on high fat diet- induced Liver Damage in Adult Wistar Rats

2021 ◽  
Vol 25 (3) ◽  
pp. 327-331
Author(s):  
P.O. Onyilo ◽  
S.O. Innih ◽  
G. Ihemeson ◽  
L.U. Ogereka ◽  
S.M. Nweke ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Liver Damage ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Date Palm ◽  
Wistar Rat ◽  
Phoenix Dactylifera ◽  
High Dose ◽  
High Fat ◽  
Standard Drug

Elevated cholesterol level is a major cause of disease burden in developing Nations. This study seeks to evaluate the ameliorative and hepatoprotective potentials of aqueous extract of date palm (Phoenix dactylifera) on high fat diet-induced liver damage. Thirty (30) adult wistar rats weighing 110-180g were randomly divided into six group of five animals each, group A served as control while B was exposed to high fat diet only (using margarine brand); Groups C, D and E were given high fat diet with co-treated with the extract at low, medium and high doses respectively while group F was received the drug Atrovastin as a gold standard to enable comparative effects of date palm administration. At the end of the treatment period, the animals were anaesthetized using chloroform blood samples were collected via cardiac puncture to investigate the activities of liver enzymes, and liver tissue was harvested through a midline incision for histological analysis. There were evidence of vascular congestion and periportal infiltration in rats given margarineonly indicative of hepatocellular disruption. Animals that received moderate to high dose of the fruit extract show mild to total reversal of the damaged liver cells and activation of kupffer cells with concurrent changes in serum albumin level. Aqueous extract of phoenix dactylifera was seen to ameliorate the fat induced liver damage with notable changes in hepatocyte configuration as observed when treated with standard drug. Keywords: Phoenix dactylifera, Hyperlipedermia, Liver, Wistar rat

scholarly journals Effect of aqueous extract of Colocasia esculenta against high-fat diet-induced non-alcoholic fatty liver disease in rats

2020 ◽  
Vol 10 (4) ◽  
Author(s):  
Somasekhar Reddy Kanala ◽  
Sudheer Akkiraju ◽  
Likitha Sree Pamisetty ◽  
Pradeepkumar Bhupalam ◽  
Deepthi Dharmavaram ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Aqueous Extract ◽  
High Fat Diet ◽  
Fatty Liver Disease ◽  
Colocasia Esculenta ◽  
High Fat ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Hepatoprotective and cytotoxicity properties of aqueous extract of Glycyrrhiza glabra in Wistar rats fed with high-fat diet

2019 ◽  
Vol 28 (5) ◽  
pp. 1305-1312 ◽  
Author(s):  
Samaneh Goorani ◽  
Hassan Morovvati ◽  
Niloofar Seydi ◽  
Maryam Almasi ◽  
Amir Amiri-Paryan ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Glycyrrhiza Glabra ◽  
High Fat

Histological Effects of Aqueous Extract of Moringa oleifera on the Liver Tissues of Wistar rats fed with High Fat Diet

2017 ◽  
Vol 2 (2) ◽  
pp. 1
Author(s):  
Obayuwana E, Obayuwana E, Ubehenin A.E, Innih S.O, Iwee R, Eidaghese E.C
Keyword(s):  
Body Weight ◽  
Liver Disease ◽  
Fatty Liver ◽  
Aqueous Extract ◽  
High Fat Diet ◽  
Fatty Liver Disease ◽  
Moringa Oleifera ◽  
High Fat ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Moringa oleifera belongs to family of moringaceae and is considered as one of the world’s most useful trees, as almost every part of the plant can be used for either as food, or therapeutic purposes. Fatty diet is a significant factor in the pathogenesis of non-alcoholic fatty Liver disease (NAFLD). The study was designed to examine histological effects of aqueous extract of Moringa oleifera on the liver tissues of wistar rat fed with high fat diet. Twenty five adult rats were divided into five groups of five animals each .While group A received distilled water daily only, groups Band C received aqueous extract of Moringa oleifera at doses of 200 mg/kg body weight and fat high diet (30% w/w of the total mash feed) respectively for a duration of seventy days. Others (groups D and E) received aqueous extract of Moringa oleifera at doses of 200 mg/kg body weight and fat high diet for a duration of seventy days. Histology of the liver of the rats fed with high fat diet exhibited significant changes in the architecture of liver tissue. The changes include micro and macro vascular steatosis, increased fatty infiltration, inflammation, sinusoidal dilation, degeneration of veins and vacuolization as compared to normal liver histology. Treatment with 200 mg/kg extract of Moringa oleifera significantly attenuated these effects imposed by high fat diet as compared to the control group. Therefore demonstrated that daily administration of Moringa oleifera leaves extract to rats for a period of 70 days may reverse the formation of hepatic steatosis in non-alcoholic fatty liver disease.

Hepatoprotective potential of aqueous extract of Allium eriophyllum Boiss in high-fat diet-induced fatty liver diseases

2018 ◽  
Vol 28 (4) ◽  
pp. 963-969 ◽  
Author(s):  
Samaneh Goorani ◽  
Mohsen Zhaleh ◽  
Majid Hajialiani ◽  
Rohallah Moradi ◽  
Mohammad Kazem Koohi ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Aqueous Extract ◽  
High Fat Diet ◽  
Liver Diseases ◽  
High Fat ◽  
Allium Eriophyllum Boiss

scholarly journals Effect of an aqueous extract of Chrysobalanus icaco on the adiposity of Wistar rats fed a high-fat diet

2020 ◽  
Author(s):  
Keciany Alves ◽  
Heloisa Helena Pessoa Portela-de-Sá ◽  
Paula Alexandre de Freitas ◽  
Yuri de Abreu Gomes-Vasconcelos ◽  
Renata Prado Vasconcelos ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat
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