Chondrosarcomas of the small bones: analysis of 44 patients

Aims. Fibrous dysplasia (FD) is a benign fibro-osseous neoplasm that most commonly arises in the ribs, femur, and craniofacial bones. We analyzed features of FD arising in the spine/short tubular/small bones of the hands/feet (STSBHF), specifically assessing for pattern of bone formation (conventional, complex/anastomosing, psammomatoid/cementum like), myxoid change, and presence of osteoclast-type giant cells. Materials and methods. A total of 1958 cases of FD were reviewed, of which 131 arose in the spine/STSBHF representing 2.5% of institutional and 10% of consultation cases, respectively. Eighty-six cases had material available for review. Anatomic sites included vertebrae ( n = 58, 67%), short tubular bones ( n = 20, 23%), and small bones of the hands/feet ( n = 8, 9%). The most common morphologic pattern of bone identified was conventional ( n = 77, 90%), followed by complex/anastomosing ( n = 22, 26%) and psammomatoid/cementum like ( n = 22, 26%). Eighteen cases (21%) had matrix-poor areas. Hypercellular areas were identified in 6 cases, 2 cases of which showed matrix-poor areas. Osteoclast-type giant cells were noted in 9 cases and myxoid change was present in 3 cases. Radiologic imaging studies available for 41 cases nearly all demonstrated features typical of FD, but the diagnosis was not predicted due to the unexpected location. Conclusions. FD arising in the spine/STSBHF is rare and frequently results in expert consultation. A significant number of cases exhibited less commonly recognized patterns of bone formation, and stromal changes including osteoclast-type giant cells, and matrix poor areas. Furthermore, imaging features in the STSBHF are often less specific. Awareness of the morphologic spectrum at these locations coupled with radiologic correlation should aid in accurate classification.

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Observations on the effects which take place from the destruction of the membrana tympani of the ear. By Mr. Astley Cooper. In a letter to Everard Home, Esq. F. R. S., by whom some remarks are added

Abstracts of the Papers Printed in the Philosophical Transactions of the Royal Society of London ◽

10.1098/rspl.1800.0007 ◽

1832 ◽

Vol 1 ◽

pp. 10-11 ◽

Cited By ~ 1

Keyword(s):

Small Bones ◽

The Right

The case to which we owe the observations contained in this paper, is that of a youth, who at the age of ten was attacked with an inflammation and suppuration in the left ear, which continued discharging matter for several weeks; and who after the space of about a twelvemonth had the same symptoms in his right ear, the discharge in both cases being thin and fetid, and conveying many small bones and particles of bones. On probing the ears when the youth was about twenty years of age, it was found that the membrane tympani of the left ear was totally destroyed, and that but a small part of it remained in the right ear. So free was the passage through both the ears, that the patient, by closing his nostrils and contracting his cheeks, could with ease force the air from the mouth through the meatus auditorius; and yet what is most remarkable, the sense of hearing was by no means materially impaired by this imperfection; especially in the left ear, where the whole of the membrane was dissolved. The organ even retained a nice musical discrimination.

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Lesion with blue bone-a case report

Journal of Pathology of Nepal ◽

10.3126/jpn.v8i1.19464 ◽

2018 ◽

Vol 8 (1) ◽

pp. 1323-1325

Author(s):

Laila Mohamed Ilias ◽

Babitha Alingal Mohammed ◽

Roshini PS ◽

Anupama Ponniah ◽

Poornima Vijayan

Keyword(s):

Histopathological Examination ◽

Fibrous Tissue ◽

Bone Lesion ◽

Metacarpal Bone ◽

Cortical Surface ◽

Bizarre Parosteal Osteochondromatous Proliferation ◽

X Ray ◽

Spindle Cells ◽

Small Bones ◽

Hands And Feet

Bizzare parosteal osteochondromatous proliferation, or Nora‘s lesion is a unique bone lesion that most often arises in the small bones of hands and feet. It is characterised by proliferation of chondroid, bony and fibrous tissue, and is occasionally misdiagnosed as a malignant process. Our case was a 31 yr old lady, who presented with a painless swelling near the 5th metacarpal bone of right hand. X-ray showed well marginated mineralised mass arising from the cortical surface of the metacarpal bone. Histopathological examination revealed bizarre parosteal osteochondromatous proliferation composed of varying amounts of cartilage, bone and spindle cells. Cartilage was hypercellular and chondrocytes were enlarged. Ossification was irregular and had a peculiar blue tinctorial quality.

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DXA measurements in rett syndrome reveal small bones with low bone mass

Journal of Bone and Mineral Research ◽

10.1002/jbmr.423 ◽

2011 ◽

Vol 26 (9) ◽

pp. 2280-2286 ◽

Cited By ~ 27

Author(s):

Gitte Roende ◽

Kirstine Ravn ◽

Kathrine Fuglsang ◽

Henrik Andersen ◽

Jytte Bieber Nielsen ◽

...

Keyword(s):

Bone Mass ◽

Rett Syndrome ◽

Low Bone Mass ◽

Small Bones

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Giant Cell Tumor of the Talar Neck

Journal of the American Podiatric Medical Association ◽

10.7547/0970225 ◽

2007 ◽

Vol 97 (3) ◽

pp. 225-228 ◽

Cited By ~ 7

Author(s):

Hakan Selek ◽

Hamza Özer ◽

Sacit Turanli ◽

Özlem Erdem

Keyword(s):

Giant Cell Tumor ◽

Giant Cell ◽

Clinical Signs ◽

Cell Tumor ◽

Giant Cell Tumors ◽

Radiographic Appearance ◽

Aneurysmal Bone Cysts ◽

Tumors Of Bone ◽

Brown Tumors ◽

Small Bones

We describe a patient with a giant cell tumor in the talar head and neck of the left foot who was diagnosed as having osteochondritis dissecans and treated with arthroscopic drilling in this same location 3 years earlier. Giant cell tumors can be confused with several conditions, including giant cell reparative granulomas, brown tumors, and aneurysmal bone cysts. Giant cell tumors of bone typically occur in the epiphysis of long bones, including the distal femur and proximal tibia. They are uncommonly found in the small bones of the foot or ankle, and talar involvement is rare. Despite this rarity, the radiographic appearance and clinical signs of talar lesions should be considered in the differential diagnosis of nontraumatic conditions in the foot. (J Am Podiatr Med Assoc 97(3): 225–228, 2007)

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The Devonian actinopterygianCheirolepisAgassiz

Earth and Environmental Science Transactions of the Royal Society of Edinburgh ◽

10.1017/s0080456800012850 ◽

1979 ◽

Vol 70 (13-14) ◽

pp. 337-399 ◽

Cited By ~ 56

Author(s):

D. Michael Pearson ◽

T. Stanley Westoll

Keyword(s):

Body Shape ◽

Upper Devonian ◽

Specific Level ◽

Red Sandstone ◽

Incertae Sedis ◽

Mode Of Life ◽

Interesting Variation ◽

Small Bones ◽

Rostral Region ◽

Head Skeleton

SynopsisThe structure of the fishes constituting the Devonian genusCheirolepisis investigated. Articulated remains from the Scottish Old Red Sandstone and the Canadian Upper Devonian were studied and two species are recognised, the Middle DevonianC. trailliand the Upper DevonianC. canadensis.Recently described fragmentary material from Europe assigned to the genus is best regarded asincertae sedis. Cheirolepisis the earliest actinopterygian genus with extensive material. Neurocranial remains are described, with a crossopterygian-like parasphenoid. There seems to have been a mobile rostral region with several small bones between premaxilla and postrostral extending to the anterior corner of the small dermal orbit. New palatoquadrate and pectoral girdle material is described. The apparently primitive nature of the head skeleton is related to the cranial dynamics and the likely mode of life. The small scales and the elongate-fusiform body shape are a corollary of the method of swimming. The ecology of the fishes is touched upon. A taxonomic investigation of the two species was carried out but although interesting variation in the scale-row numbers came to light no changes at the specific level were deemed necessary. Revised generic and specific diagnoses are given.

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Chondrosarcoma of the Small Bones of the Hands and Feet

High-Yield Bone and Soft Tissue Pathology ◽

10.1016/b978-1-4377-2520-9.10043-6 ◽

2012 ◽

pp. 96-98

Keyword(s):

Small Bones ◽

Hands And Feet

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Ewing's Sarcoma: An Approach to Radiological Diagnosis

Tumori Journal ◽

10.1177/030089167906500316 ◽

1979 ◽

Vol 65 (3) ◽

pp. 389-399 ◽

Cited By ~ 7

Author(s):

Fabrizio Lombardi ◽

Marco Gasparini ◽

Cristina Gianni ◽

Raffaele Petrillo ◽

John David Tesoro-Tess ◽

...

Keyword(s):

Ewing’S Sarcoma ◽

Ewing's Sarcoma ◽

Primary Site ◽

Long Bones ◽

Age Group ◽

Pediatric Age Group ◽

Localized Disease ◽

The Mean ◽

Small Bones

All the pertinent radiographs of 83 patients with histologically proven Ewing's sarcoma were reviewed. Forty-nine patients were in the pediatric age group, and 34 were adults. The mean age, the symptoms and time from symptoms to diagnosis were evaluated in the 2 groups. The site of primary involvement was in 54 % the long bones, 35 % the flat bones, 8 % the small bones and 3 % extraosseous. For the primary site we considered the diagnostic results of the standard radiographic investigations and in some cases the usefulness of angiography, xeroradiography and telethermography. At presentation we also evaluated the possible diffusion of the disease with standard radiographic surveys (chest and skeletal, including limbs) and with foot lymphography in selected cases. In this way, 57 patients (69 %) were considered to have localized disease. In this group, we also considered the value of the periodic radiographic follow-up, which enabled us to disclose the appearance of metastases (chest 64 %, bone 54 %, lymph nodes 11 %) in 28 cases (49 %). Finally, we made a comparison of the different radiologic and epidemiologic findings between children and adults.

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Anatomic three-dimensional model-assisted surgical planning for treatment of pediatric hip dislocation due to osteomyelitis

Journal of International Medical Research ◽

10.1177/0300060519854288 ◽

2019 ◽

Vol 48 (2) ◽

pp. 030006051985428 ◽

Cited By ~ 1

Author(s):

Yi-Ping Wei ◽

Yu-Cheng Lai ◽

Wei-Ning Chang

Keyword(s):

Three Dimensional ◽

Hip Dislocation ◽

Three Dimensional Model ◽

Limb Deformity ◽

Joint Deformity ◽

3D Printed ◽

Small Bones ◽

Hip Spica Cast ◽

Pediatric Orthopedic ◽

The Right

Management of pediatric septic coxarthritis and osteomyelitis of the femur is challenging, and the sequelae of multiplanar hip joint deformity with instability are difficult to reconstruct. The inadequacy of a suitable device for fixing small bones during pediatric osteotomy is a hindrance to the correction of subluxated hip joints and deformed femurs in children. Two-dimensional axial images and three-dimensional (3D) virtual models representing the patient’s individual anatomy are usually reserved for more complex cases of limb deformity. 3D printing technology can be used for preoperative planning of complex pediatric orthopedic surgery. However, there is a paucity of literature reports regarding the application of 3D-printed bone models for pediatric post-osteomyelitis deformity. We herein present a case of a 4-year-old boy who underwent treatment for post-osteomyelitis deformity. We performed corrective surgery with Pemberton osteotomy of the right hip, multilevel varus derotation osteotomy of the right femur, and immobilization with a hip spica cast. A 3D-printed bone model of this patient was used to simulate the surgery, determine the proper osteotomy sites, and choose the appropriate implant for the osteotomized bone. A satisfactory clinical outcome was achieved.

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