Association between Osteoprotegerin and Charcot Neuroarthropathy: a systematic review

2021 ◽  
Author(s):  
Renata Ochoa-Précoma ◽  
Blanca T. Pacheco-Soto ◽  
Leonardo M. Porchia ◽  
Enrique Torres-Rasgado ◽  
Ricardo Pérez-Fuentes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Charcot Neuroarthropathy

scholarly journals Mid- to long-term outcomes of contemporary total knee arthroplasty in Charcot neuroarthropathy: a systematic review and meta-analysis

2021 ◽  
Vol 6 (7) ◽  
pp. 556-564
Author(s):  
Piti Rattanaprichavej ◽  
Patapong Towiwat ◽  
Artit Laoruengthana ◽  
Piyameth Dilokthornsakul ◽  
Nathorn Chaiyakunapruk
Keyword(s):  
Systematic Review ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Meta Analysis ◽  
Ligament Injury ◽  
Charcot Neuroarthropathy ◽  
Implant Survivorship ◽  
Total Knee ◽  
Component Revision ◽  
End Stage

Total knee arthroplasty (TKA) is an effective procedure to treat many patients with end-stage knee arthropathy. However, the extension of TKA for patients with Charcot neuroarthropathy (CNA) is controversial, with relatively limited evidence defining optimal reconstruction techniques. This systematic review of relevant studies that were published from January 2000 to June 2020 aimed to define survivorship, complications, reoperation, and component revision rates of contemporary TKA performed for CNA. We identified 127 TKA performed for CNA in five studies that comprised ≥ 7 knees with ≥ 5 years of follow-up. Overall implant survivorship was 85.4%. The overall complication rate was 26.4%, with the most common complications including instability (24.0%), periprosthetic fracture (17.4%), infection (13.0%), ligament injury (10.9%) and aseptic loosening (10.9%). The aetiology of CNA and prosthesis type had no influence on clinical outcomes, whereas the effect of staging of disease and ataxia status was still inconclusive. Understanding the potential determinants, survivorship and risk of complications related to TKA performed in CNA may help surgeons to deal with patient expectations. Cite this article: EFORT Open Rev 2021;6:556-564. DOI: 10.1302/2058-5241.6.200103

A Systematic Review of Current Surgical Interventions for Charcot Neuroarthropathy of the Midfoot

2017 ◽  
Vol 56 (6) ◽  
pp. 1249-1252 ◽  
Author(s):  
Pejma Shazadeh Safavi ◽  
Daniel C. Jupiter ◽  
Vinod Panchbhavi
Keyword(s):  
Systematic Review ◽  
Surgical Interventions ◽  
Charcot Neuroarthropathy

A Systematic Review of Angular Deformities in Charcot Neuroarthropathy

2020 ◽  
Author(s):  
Nicole K. Cates ◽  
Jonathan Tenley ◽  
Helene R. Cook ◽  
Paul J. Kim
Keyword(s):  
Systematic Review ◽  
Charcot Neuroarthropathy ◽  
Angular Deformities

Surgical Management of Charcot Neuroarthropathy of the Foot and Ankle: A Systematic Review

2012 ◽  
Vol 33 (2) ◽  
pp. 113-121 ◽  
Author(s):  
Nicholas J. Lowery ◽  
Jason B. Woods ◽  
David G. Armstrong ◽  
Dane K. Wukich
Keyword(s):  
Systematic Review ◽  
Surgical Management ◽  
Foot And Ankle ◽  
Charcot Neuroarthropathy

scholarly journals Systematic review of techniques to monitor remission of acute Charcot neuroarthropathy in people with diabetes

2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Catherine Gooday ◽  
Katie Gray ◽  
Frances Game ◽  
Jim Woodburn ◽  
Fiona Poland ◽  
...  
Keyword(s):  
Systematic Review ◽  
Charcot Neuroarthropathy

Surgical treatment of midfoot Charcot neuroarthropathy with osteomyelitis in patients with diabetes: a systematic review

2020 ◽  
Vol 29 (Sup6) ◽  
pp. S19-S28
Author(s):  
Crystal L. Ramanujam ◽  
Alan C. Stuto ◽  
Thomas Zgonis
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Surgical Treatment ◽  
External Fixation ◽  
Revisional Surgery ◽  
Cochrane Library ◽  
Soft Tissue Reconstruction ◽  
Charcot Neuroarthropathy ◽  
Wide Range ◽  
Patients With Diabetes

Objective: A wide range of clinical presentations of Charcot neuroarthropathy of the foot with concomitant osteomyelitis in patients with diabetes has been described. Existing literature provides an equally diverse list of treatment options. The purpose of this systematic review was to assess the outcomes specifically for the surgical management of midfoot Charcot neuroarthropathy with osteomyelitis in patients with diabetes. Method: A systematic review was conducted by three independent reviewers using the following databases and search engines: Cumulative Index of Nursing and Allied Health Literature (CINAHL), Cochrane Library, EMBASE (Excerpta Medica dataBASE), Google Scholar, Ovid, PubMed and Scopus. Search terms used were: Charcot neuroarthropathy, osteoarthropathy, neuro-osteoarthropathy, neurogenic arthropathy, osteomyelitis, midfoot, foot, ankle, diabetes mellitus, ulceration, wound, infection, surgical offloading, diabetic reconstruction, internal fixation, external fixation. Studies meeting the following criteria were included: English language studies, studies published from 1997–2017, patients with diabetes mellitus surgically treated for Charcot neuroarthropathy of the midfoot (specified location) with concomitant osteomyelitis, with or without internal and/or external fixation, follow-up period of six months or more postoperatively, documentation of healing rates, complications, and need for revisional surgery. Studies which were entirely literature reviews, descriptions of surgical-only technique and/or cadaveric studies, patients without diabetes, studies that did not specify location of osteomyelitis and Charcot neuroarthropathy, and treatment proximal to and including Chopart's/midtarsal joint specifically talonavicular, calcaneocuboid, subtalar, ankle were excluded. Results: A total of 13 selected studies, with a total of 114 patients with diabetes of which 56 had surgical treatment for midfoot Charcot neuroarthropathy with osteomyelitis, met the above inclusion criteria and were used for data extraction. Conclusion: Surgical intervention for midfoot Charcot neuroarthropathy with osteomyelitis in patients with diabetes demonstrated a relatively high success rate for a range of procedures including debridement with simple exostectomy, arthrodesis with or without internal or external fixation, and advanced soft tissue reconstruction. However, this systematic review emphasises the need for larger, better designed studies to investigate the efficacy and failure rates of surgical treatment in this group of patients.

scholarly journals Management of Ankle Charcot Neuroarthropathy: A Systematic Review

2021 ◽  
Vol 10 (24) ◽  
pp. 5923
Author(s):  
Ahmed ElSayed Galhoum ◽  
Vineet Trivedi ◽  
Mohamed Askar ◽  
Sergio Tejero ◽  
Mario Herrera-Pérez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Management ◽  
Current Practice ◽  
Inclusion Criteria ◽  
Management Options ◽  
Surgical Interventions ◽  
Articular Fracture ◽  
Charcot Neuroarthropathy ◽  
Pubmed Search ◽  
Repetitive Trauma

Background: Charcot neuroarthropathy is a non-infective, destructive process occurring in patients rendered insensate by peripheral neuropathy, which is caused mainly by diabetes. Repetitive trauma from standing and walking provides a neuro-traumatic stimulus that leads to dislocation, or peri-articular fracture, or both, within the ankle. This review concentrates on the management protocols regarding the ankle only. Methods: A Pubmed search for clinical trials performed to manage ankle Charcot neuroarthropathy and a systematic review of these articles were undertaken. Results: Twenty papers met the inclusion criteria: four of them describe non-surgical management, while the rest show different surgical management options of ankle Charcot neuroarthropathy. Conclusions: Surgical algorithms for the treatment of CN of the ankle are based almost entirely on level four. There is inconclusive evidence concerning the timing of treatment and the use of different fixation methods. Instability and ulceration are the main precursors for surgical interventions. Prospective series and randomized studies, albeit difficult to perform, are necessary to support and strengthen current practice.

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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