Phosphorus and chlorine co-doped carbon dots with strong photoluminescence as a fluorescent probe for ferric ions

2018 ◽  
Vol 186 (1) ◽  
Author(s):  
Weijie Wang ◽  
Jiawei Peng ◽  
Feiming Li ◽  
Bingyuan Su ◽  
Xi Chen ◽  
...  
2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.


2020 ◽  
Vol 44 (6) ◽  
pp. 2350-2356 ◽  
Author(s):  
Nan Wang ◽  
Mengke Wang ◽  
Yang Yu ◽  
Guojian Yang ◽  
Xingguang Su

A simple and sensitive sensing strategy for sialic acid activity detection on the basis of novel near-infrared B,N co-doped carbon dots was constructed.


RSC Advances ◽  
2018 ◽  
Vol 8 (74) ◽  
pp. 42361-42373 ◽  
Author(s):  
Suraj Konar ◽  
Dipanjan Samanta ◽  
Subhajit Mandal ◽  
Subhayan Das ◽  
Madhusudan Kr Mahto ◽  
...  

Nitrogen and sulfur co-doped carbon dots (NSCDs) have been used as a fluorescent probe for the sensitive and selective detection of clinically important organic aldehyde cinnamaldehyde.


2020 ◽  
Vol 12 (42) ◽  
pp. 5110-5119
Author(s):  
Shanshan Wei ◽  
Tinghua Li ◽  
Xinyu Zhang ◽  
Hongyuan Zhang ◽  
Chunzhu Jiang ◽  
...  

Nitrogen and sulfur co-doped carbon dots (N,S-CDs) as a simple “on–off–on” fluorescent probe were applied for quickly detecting Cu2+ ions and GSH in living cells.


Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3470
Author(s):  
Thi Hoa Le ◽  
Hyun Jong Lee ◽  
Ji Hyeon Kim ◽  
Sang Joon Park

Carbon dots (CDs) demonstrate very poor fluorescence quantum yield (QY). In this study, with the help of a hydrothermal method, we combined CDs with nitrogen and phosphorus elements belonging to the VA group (in the periodic table) to form heteroatom co-doped CDs, i.e., nitrogen and phosphorus co-doped carbon dots (NPCDs). These displayed a significant improvement in the QY (up to 84%), which was as much as four times than that of CDs synthesized by the same method. The as-prepared NPCDs could be used as an “off-on” fluorescence detector for the rapid and effective sensing of ferric ions (Fe3+) and catecholamine neurotransmitters (CNs) such as dopamine (DA), adrenaline (AD), and noradrenaline (NAD). The fluorescence of NPCDs was “turned off” and the emission wavelength was slightly red-shifted upon increasing the Fe3+ concentration. However, when CNs were incorporated, the fluorescence of NPCDs was recovered in a short response time; this indicated that CN concentration could be monitored, relying on enhancing the fluorescence signal of NPCDs. As a result, NPCDs are considered as a potential fluorescent bi-sensor for Fe3+ and CN detection. Particularly, in this research, we selected DA as the representative neurotransmitter of the CN group along with Fe3+ to study the sensing system based on NPCDs. The results exhibited good linear ranges with a limit of detection (LOD) of 0.2 and 0.1 µM for Fe3+ and DA, respectively.


Sign in / Sign up

Export Citation Format

Share Document