The emergence in Japan of Sathuperi virus , a tropical Simbu serogroup virus of the genus Orthobunyavirus

The Simbu serogroup is one of the serogroups that belong to the Orthobunyavirus genus of the family Peribunyaviridae. Simbu serogroup viruses are transmitted mainly by Culicoides biting midges. Meager information is available on Simbu serogroup virus infection in ruminants in Sudan. Therefore, in this study, serological surveillance of Simbu serogroup viruses in cattle in seven states in Sudan was conducted during the period from May, 2015, to March, 2016, to shed some light on the prevalence of this group of viruses in our country. Using a cross-sectional design, 184 cattle sera were collected and tested by a commercial SBV ELISA kit which enables the detection of antibodies against various Simbu serogroup viruses. The results showed an overall 86.4% prevalence of antibodies to Simbu serogroup viruses in cattle in Sudan. Univariate analysis showed a significant association ( p = 0.007 ) between ELISA seropositivity and states where samples were collected. This study suggests that Simbu serogroup virus infection is present in cattle in Sudan. Further epizootiological investigations on Simbu serogroup viruses infection and virus species involved are warranted.

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Characterization of Simbu serogroup virus infections in type I interferon receptor knock-out mice

Archives of Virology ◽

10.1007/s00705-017-3475-1 ◽

2017 ◽

Vol 162 (10) ◽

pp. 3119-3129 ◽

Cited By ~ 2

Author(s):

Kerstin Tauscher ◽

Kerstin Wernike ◽

Melina Fischer ◽

Anne Wegelt ◽

Bernd Hoffmann ◽

...

Keyword(s):

Type I Interferon ◽

Type I ◽

Virus Infections ◽

Knock Out ◽

Simbu Serogroup ◽

Interferon Receptor ◽

Serogroup Virus ◽

Knock Out Mice

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Nucleotide sequence and deduced amino acid sequence of the medium RNA segment of Oropouche, a Simbu serogroup virus: Comparison with the middle RNA of Bunyamwera and California serogroup viruses

Virus Research ◽

10.1016/s0168-1702(00)00234-3 ◽

2001 ◽

Vol 73 (2) ◽

pp. 153-162 ◽

Cited By ~ 6

Author(s):

Heiman Wang ◽

David W.C. Beasley ◽

Li Li ◽

Michael R. Holbrook ◽

Alan D.T. Barrett

Keyword(s):

Amino Acid ◽

Nucleotide Sequence ◽

Amino Acid Sequence ◽

Simbu Serogroup ◽

Serogroup Virus ◽

California Serogroup

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Circulation of a Simbu Serogroup Virus, Causing Schmallenberg Virus-Like Clinical Signs in Northern Jordan

Transboundary and Emerging Diseases ◽

10.1111/tbed.12468 ◽

2015 ◽

Vol 64 (4) ◽

pp. 1095-1099 ◽

Cited By ~ 7

Author(s):

S. M. Abutarbush ◽

A. La Rocca ◽

K. Wernike ◽

M. Beer ◽

K. AL Zuraikat ◽

...

Keyword(s):

Clinical Signs ◽

Schmallenberg Virus ◽

Simbu Serogroup ◽

Serogroup Virus ◽

Northern Jordan

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Characterization of Unknown Orthobunya-Like Viruses from India

Viruses ◽

10.3390/v10090451 ◽

2018 ◽

Vol 10 (9) ◽

pp. 451 ◽

Cited By ~ 2

Author(s):

Shannon Whitmer ◽

Pragya Yadav ◽

Prasad Sarkale ◽

Gouri Chaubal ◽

Alicia Francis ◽

...

Keyword(s):

Next Generation Sequencing ◽

Febrile Illness ◽

Geographic Region ◽

Emerging Viruses ◽

Simbu Serogroup ◽

Isolation And Characterization ◽

Karnataka State ◽

Next Generation Sequencing Ngs ◽

Generation Sequencing

Next-generation sequencing (NGS) of agents causing idiopathic human diseases has been crucial in the identification of novel viruses. This study describes the isolation and characterization of two novel orthobunyaviruses obtained from a jungle myna and a paddy bird from Karnataka State, India. Using an NGS approach, these isolates were classified as Cat Que and Balagodu viruses belonging to the Manzanilla clade of the Simbu serogroup. Closely related viruses in the Manzanilla clade have been isolated from mosquitos, humans, birds, and pigs across a wide geographic region. Since Orthobunyaviruses exhibit high reassortment frequency and can cause acute, self-limiting febrile illness, these data suggest that human and livestock infections of the Oya/Cat Que/Manzanilla virus may be more widespread and/or under-reported than anticipated. It therefore becomes imperative to identify novel and unknown viruses in order to understand their role in human and animal pathogenesis. The current study is a step forward in this regard and would act as a prototype method for isolation, identification and detection of several other emerging viruses.

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