Complete genome characterization of porcine epidemic diarrhea virus in Vietnam

2015 ◽  
Vol 160 (8) ◽  
pp. 1931-1938 ◽  
Author(s):  
Dam Thi Vui ◽  
To Long Thanh ◽  
Nguyen Tung ◽  
Anchalee Srijangwad ◽  
Thitima Tripipat ◽  
...  
2018 ◽  
Vol 6 (10) ◽  
Author(s):  
Jun Woo Park ◽  
Sung J. Yoo ◽  
Taeyong Kwon ◽  
Youngkwang Moon ◽  
Young S. Lyoo

ABSTRACT Nationwide porcine epidemic diarrhea virus (PEDV) outbreaks occurred in late 2013 in the Republic of Korea, resulting in an expansion of genomic data for Korean PEDVs. However, the data available for Korean PEDVs before 2013 are insufficient. Therefore, we sequenced and analyzed the complete genome of a Korean PEDV strain, KUPE21, which was isolated in the early 2000s.


Virology ◽  
2017 ◽  
Vol 500 ◽  
pp. 50-61 ◽  
Author(s):  
Baochao Fan ◽  
Zhengyu Yu ◽  
Fengjiao Pang ◽  
Xiangwei Xu ◽  
Baimeng Zhang ◽  
...  

Virus Genes ◽  
2017 ◽  
Vol 54 (2) ◽  
pp. 215-224 ◽  
Author(s):  
Rocío Lara-Romero ◽  
Luis Gómez-Núñez ◽  
José Luis Cerriteño-Sánchez ◽  
Laura Márquez-Valdelamar ◽  
Susana Mendoza-Elvira ◽  
...  

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Yu Wu ◽  
Wei Li ◽  
Qingfeng Zhou ◽  
Qunhui Li ◽  
Zhichao Xu ◽  
...  

Abstract Background Porcine epidemic diarrhea virus (PEDV) has caused enormous economic losses to the global pig industry. Currently available PEDV vaccine strains have limited protective effects against PEDV variant strains. Methods In this study, the highly virulent epidemic virus strain CT was serially passaged in Vero cells for up to 120 generations (P120). Characterization of the different passages revealed that compared with P10 and P64, P120 had a higher viral titer and more obvious cytopathic effects, thereby demonstrating better cell adaptability. Results Pathogenicity experiments using P120 in piglets revealed significant reductions in clinical symptoms, histopathological lesions, and intestinal PEDV antigen distribution; the piglet survival rate in the P120 group was 100%. Furthermore, whole-genome sequencing identified 13 amino acid changes in P120, which might be responsible for the attenuated virulence of P120. Conclusions Thus, an attenuated strain was obtained via cell passaging and that this strain could be used in preparing attenuated vaccines.


1992 ◽  
Vol 54 (2) ◽  
pp. 313-318 ◽  
Author(s):  
Ko-ichi KUSANAGI ◽  
Hiroyoshi KUWAHARA ◽  
Tetsuo KATOH ◽  
Tetsuo NUNOYA ◽  
Yoshihisa ISHIKAWA ◽  
...  

2012 ◽  
Vol 86 (10) ◽  
pp. 5964-5964 ◽  
Author(s):  
S.-J. Park ◽  
H.-K. Kim ◽  
D.-S. Song ◽  
D.-J. An ◽  
B.-K. Park

2017 ◽  
Vol 5 (27) ◽  
Author(s):  
Yibin Qin ◽  
Bingxia Lu ◽  
Ying He ◽  
Bin Li ◽  
Qunpeng Duan ◽  
...  

ABSTRACT We report here the complete genome sequence of porcine epidemic diarrhea virus (PEDV) strain CH/GX/2015/750A (750A), which was isolated from a suckling piglet with watery diarrhea in Guangxi, China. The isolate is genetically close to other recent Chinese variant PEDVs and distinct from the classical PEDVs.


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