Genome-wide gene expression profiling of tongue squamous cell carcinoma by RNA-seq

2017 ◽  
Vol 22 (1) ◽  
pp. 209-216 ◽  
Author(s):  
Hai Xia Zhang ◽  
Ou Sheng Liu ◽  
Chao Deng ◽  
Yan He ◽  
Ye Qian Feng ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Gene Expression Profiling ◽  
Squamous Cell ◽  
Expression Profiling ◽  
Tongue Squamous Cell Carcinoma ◽  
Rna Seq ◽  
Genome Wide ◽  
Genome Wide Gene Expression

scholarly journals Assessing Various Control Samples for Microarray Gene Expression Profiling of Laryngeal Squamous Cell Carcinoma

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 588
Author(s):  
Adam Ustaszewski ◽  
Magdalena Kostrzewska-Poczekaj ◽  
Joanna Janiszewska ◽  
Malgorzata Jarmuz-Szymczak ◽  
Malgorzata Wierzbicka ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Epithelial Cells ◽  
Cell Carcinoma ◽  
Gene Expression Profiling ◽  
Cell Lines ◽  
Squamous Cell ◽  
Expression Profiling ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Control Samples

Selection of optimal control samples is crucial in expression profiling tumor samples. To address this issue, we performed microarray expression profiling of control samples routinely used in head and neck squamous cell carcinoma studies: human bronchial and tracheal epithelial cells, squamous cells obtained by laser uvulopalatoplasty and tumor surgical margins. We compared the results using multidimensional scaling and hierarchical clustering versus tumor samples and laryngeal squamous cell carcinoma cell lines. A general observation from our study is that the analyzed cohorts separated according to two dominant factors: “malignancy”, which separated controls from malignant samples and “cell culture-microenvironment” which reflected the differences between cultured and non-cultured samples. In conclusion, we advocate the use of cultured epithelial cells as controls for gene expression profiling of cancer cell lines. In contrast, comparisons of gene expression profiles of cancer cell lines versus surgical margin controls should be treated with caution, whereas fresh frozen surgical margins seem to be appropriate for gene expression profiling of tumor samples.

Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma

2021 ◽  
Author(s):  
Charles C. L. Tong ◽  
Mateusz Koptyra ◽  
Pichai Raman ◽  
Komal S. Rathi ◽  
Namrata Choudhari ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Gene Expression Profiling ◽  
Squamous Cell ◽  
Expression Profiling ◽  
Inverted Papilloma ◽  
Targeted Gene Expression

scholarly journals Gene expression profiling via bioinformatics analysis reveals biomarkers in laryngeal squamous cell carcinoma

2015 ◽  
Vol 12 (2) ◽  
pp. 2457-2464 ◽  
Author(s):  
GUO-FANG GUAN ◽  
YING ZHENG ◽  
LIAN-JI WEN ◽  
DE-JUN ZHANG ◽  
DUO-JIAO YU ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Gene Expression Profiling ◽  
Squamous Cell ◽  
Expression Profiling ◽  
Bioinformatics Analysis ◽  
Laryngeal Squamous Cell Carcinoma

scholarly journals Gene expression profiling of esophageal cancer: Comparative analysis of Barrett's esophagus, adenocarcinoma, and squamous cell carcinoma

2007 ◽  
Vol 120 (9) ◽  
pp. 1914-1921 ◽  
Author(s):  
Danielle M. Greenawalt ◽  
Cuong Duong ◽  
Gordon K. Smyth ◽  
Marianne L. Ciavarella ◽  
Natalie J. Thompson ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Comparative Analysis ◽  
Cell Carcinoma ◽  
Gene Expression Profiling ◽  
Barrett’S Esophagus ◽  
Squamous Cell ◽  
Expression Profiling ◽  
Barrett's Esophagus
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