Pre-operative use of dexamethasone does not reduce incidence or intensity of bleaching-induced tooth sensitivity. A triple-blind, parallel-design, randomized clinical trial

2018 ◽  
Vol 23 (1) ◽  
pp. 435-444 ◽  
Author(s):  
Luiz Augusto da Costa Poubel ◽  
Cresus Vinicius Deppes de Gouvea ◽  
Fernanda Signorelli Calazans ◽  
Etyene Castro Dip ◽  
Wesley Veltri Alves ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Tooth Sensitivity ◽  
Parallel Design

Postoperative tooth sensitivity with a new self-adhesive resin cement—a randomized clinical trial

2012 ◽  
Vol 17 (3) ◽  
pp. 793-798 ◽  
Author(s):  
Markus B. Blatz ◽  
Francis K. Mante ◽  
Najeed Saleh ◽  
Alan M. Atlas ◽  
Sahurabh Mannan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Resin Cement ◽  
Adhesive Resin ◽  
Tooth Sensitivity ◽  
Adhesive Resin Cement

scholarly journals Coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity: A randomized clinical trial

2021 ◽  
Vol 32 (3) ◽  
pp. 105-115
Author(s):  
Karine Letícia da Silva ◽  
Elisama Sutil ◽  
Diego Hortkoff ◽  
Renata Maria Oleniki Terra ◽  
Márcia Rezende ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Repeated Measures ◽  
Rating Scale ◽  
Absolute Risk ◽  
Tooth Sensitivity ◽  
Dental Bleaching ◽  
Significance Level ◽  
Significant Difference ◽  
The Absolute

Abstract This clinical trial evaluated the effect of the coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity (TS). A triple-blind, parallel-design, randomized clinical trial was conducted on 84 patients who received ibuprofen/caffeine or placebo capsules. The drugs were administered for 48 hours, starting 1 hour before the in-office bleaching. Two bleaching sessions were performed with 35% hydrogen peroxide gel with 1-week interval. TS was recorded up to 48 hours after dental bleaching with a 0-10 visual analogic scale (VAS) and a 5-point numeric rating scale (NRS). The color was evaluated with VITA Classical and VITA Bleachedguide scales (ΔSGU) and VITA Easyshade spectrophotometer (ΔE*ab and ΔE00). The absolute risk of TS in both groups was evaluated using Fischer's exact test. Comparisons of the TS intensity (NRS and VAS data) were performed by using the Mann-Whitney test and a two-way repeated measures ANOVA, respectively. The color alteration between the groups was compared with the Student's t test. The significance level was 5%. There was no statistically significant difference between the groups for the absolute risk of TS (p = 1.00) or for the intensity of TS (p > 0.05). A bleaching of approximately 7 shade guide units was observed on the Vita Classical and Vita Bleachedguide scales, with no statistical difference between the groups. It was concluded that coadministration of ibuprofen and caffeine did not reduce the absolute risk or intensity of TS and did not interfere with the efficacy of dental bleaching.

Evaluation of the color change and tooth sensitivity in treatments that associate violet LED with carbamide peroxide 10 %: A randomized clinical trial of a split-mouth design

2020 ◽  
Vol 30 ◽  
pp. 101679
Author(s):  
Marjorie de Oliveira Gallinari ◽  
Luciano Tavares Angelo Cintra ◽  
Ana Carolina Souza Barboza ◽  
Lívia Maria Alves Valentim da Silva ◽  
Sibele de Alcantara ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Color Change ◽  
Carbamide Peroxide ◽  
Tooth Sensitivity

In-office bleaching with a two- and seven-day intervals between clinical sessions: A randomized clinical trial on tooth sensitivity

2015 ◽  
Vol 43 (4) ◽  
pp. 424-429 ◽  
Author(s):  
Eloisa Andrade de Paula ◽  
Jéssica Andressa Nava ◽  
Cheilla Rosso ◽  
Cristina Monteiro Benazzi ◽  
Karen Tamura Fernandes ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Tooth Sensitivity

Administration of Ascorbic Acid to Prevent Bleaching-induced Tooth Sensitivity: A Randomized Triple-blind Clinical Trial

2014 ◽  
Vol 39 (2) ◽  
pp. 128-135 ◽  
Author(s):  
EA de Paula ◽  
S Kossatz ◽  
D Fernandes ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Ascorbic Acid ◽  
Color Change ◽  
Absolute Risk ◽  
Tooth Sensitivity ◽  
Parallel Design ◽  
Color Changes ◽  
The Absolute ◽  
Similar Risk

SUMMARY This study evaluated the effect of ascorbic acid, 500 mg every eight hours, on bleaching-induced tooth sensitivity. A triple-blind, parallel design, and placebo-controlled randomized clinical trial was conducted on 39 adults. The pills (placebo or ascorbic acid) were administered three times per day for 48 hours; the first dose was given one hour prior to each bleaching session. Two bleaching sessions with 35% hydrogen peroxide gel were performed with a one-week interval. Tooth sensitivity was recorded up to 48 hours after bleaching. The color evaluation was performed before and 30 days after bleaching. The absolute risk and intensity of tooth sensitivity were evaluated by Fisher exact and Mann-Whitney U-tests, respectively. Color changes were evaluated by unpaired t-test (α=0.05). There were no significant differences in the absolute risk and intensity of tooth sensitivity and color change between the groups. Both groups showed a similar risk of tooth sensitivity (p>0.05). The perioperative use of an antioxidant, such as ascorbic acid (500 mg, three times daily) perorally, was not able to prevent bleaching-induced tooth sensitivity or reduce its intensity.

Effect of acidity of in-office bleaching gels on tooth sensitivity and whitening: a two-center double-blind randomized clinical trial

2017 ◽  
Vol 21 (9) ◽  
pp. 2811-2818 ◽  
Author(s):  
A. D. Loguercio ◽  
F. Servat ◽  
R. Stanislawczuk ◽  
A. Mena-Serrano ◽  
M. Rezende ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Double Blind ◽  
Tooth Sensitivity ◽  
Bleaching Gels

Comparison of Effectiveness and Sensitivity Using Two In-Office Bleaching Protocols for a 6% Hydrogen Peroxide Gel in a Randomized Clinical Trial

2017 ◽  
Vol 42 (3) ◽  
pp. 244-252 ◽  
Author(s):  
P Vildósola ◽  
F Vera ◽  
J Ramírez ◽  
J Rencoret ◽  
H Pretel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Randomized Clinical Trial ◽  
Absolute Risk ◽  
Color Variation ◽  
Tooth Sensitivity ◽  
Tooth Color ◽  
Protocol Group ◽  
Group A ◽  
Group B

SUMMARY Objective: The aim of this blinded and randomized clinical trial was to compare two application protocols (one 36-minute application vs three 12-minute applications). We then assessed the effectiveness of the bleaching and any increase in sensitivity that was induced by bleaching via a split-mouth design. Methods and Materials: Thirty patients were treated. One group had a half arch of teeth treated with a traditional application protocol (group A: 3 × 12 minutes for two sessions). The other received an abbreviated protocol (group B: 1 × 36 minutes over two sessions). Two sessions were appointed with a two-day interval between them. The tooth color was registered at each session, as well as one week and one month after completing the treatment via a spectrophotometer. This measured L*, a*, and b*. This was also evaluated subjectively using the VITA classical A1-D4 guide and VITA Bleachedguide 3D-MASTER. Tooth sensitivity was registered according to the visual analogue scale (VAS) scale. Tooth color variation and sensitivity were compared between groups. Results: Both treatments changed tooth color vs baseline. The ΔE* = 5.71 ± 2.62 in group A, and ΔE* = 4.93 ± 2.09 in group B one month after completing the bleaching (p=0.20). No statistical differences were seen via subjective evaluations. There were no differences in tooth sensitivity between the groups. The absolute risk of sensitivity reported for both groups was 6.25% (p=0.298). The intensity by VAS was mild (p=1.00). Conclusions: We used hydrogen peroxide (6%) that was light activated with a hybrid LED/laser and two different protocols (one 36-minute application vs three 12-minute applications each for two sessions). These approaches were equally effective. There were no differences in absolute risk of sensitivity; both groups reported mild sensitivity.

Efficacy of and Effect on Tooth Sensitivity of In-office Bleaching Gel Concentrations: A Randomized Clinical Trial

2013 ◽  
Vol 38 (4) ◽  
pp. 386-393 ◽  
Author(s):  
A Reis ◽  
S Kossatz ◽  
GC Martins ◽  
AD Loguercio
Keyword(s):  
Clinical Trial ◽  
Hydrogen Peroxide ◽  
Side Effects ◽  
Randomized Clinical Trial ◽  
Color Change ◽  
Absolute Risk ◽  
Tooth Sensitivity ◽  
Bleaching Gels ◽  
Shade Guide

SUMMARY With the aim of reducing the side effects of in-office bleaching agents, less-concentrated hydrogen peroxide (HP) gels have been released by manufacturers. We evaluated the tooth sensitivity (TS) and bleaching efficacy (BE) of two HP concentrations in this study. Gels containing 35% and 20% HP (HP35 and HP20, respectively) were applied on teeth of 60 caries-free patients. Color was recorded at baseline and one week after the first and second bleaching sessions using the Vita Classical shade guide. TS was recorded on a 0-4 scale. BE at each weekly recall was evaluated by Kruskall-Wallis and Mann-Whitney tests (α=0.05). Absolute risk of TS and its intensity was evaluated by Fisher exact and Mann-Whitney tests, respectively (α=0.05). After two bleaching sessions, color change of approximately eight tabs was obtained with HP35; whereas, with HP20 it was six tabs (p<0.05). Only 26.7% (HP35) and 16.7% (HP20) of the participants reported TS, and no statistical differences were detected among them. Both in-office bleaching gels showed similar TS intensity, but the 35% HP agent produced faster bleaching.

Efficacy and Safety of 10% and 16% Carbamide Peroxide Tooth-whitening Gels: A Randomized Clinical Trial

2008 ◽  
Vol 33 (6) ◽  
pp. 606-612 ◽  
Author(s):  
S. S. Meireles ◽  
S. S. Heckmann ◽  
F. L. Leida ◽  
I. S. Santos ◽  
ÁDella Bona ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Side Effect ◽  
Clinical Relevance ◽  
Efficacy And Safety ◽  
Carbamide Peroxide ◽  
Tooth Whitening ◽  
Tooth Sensitivity

Clinical Relevance This clinical trial suggests that two carbamide peroxide concentrations, when used once a day for three weeks, were well tolerated by patients and were effective in tooth whitening. Although some tooth sensitivity occurred during treatment, this side effect was mostly mild and transient.

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