Comparison between one-session root canal treatment with aPDT and two-session treatment with calcium hydroxide-based antibacterial dressing, in dog’s teeth with apical periodontitis

Background: This is a systematic review to assess and provide a pooled effect estimate, if possible, for the effects of triple antibiotic paste as an intra-canal medication for root canal treatment of mature permanent non-vital teeth with apical periodontitis. This review will assess post-operative pain, flare-up incidence, and clinical and radiographic healing. Methods: Nine electronic databases (Pubmed, CENTRAL, VHL, Scopus, EBSCOhost, Web of Science, Trip, OpenGrey, Proquest) were searched along with two major clinical trial registries. Conference proceedings, reference lists and citations of the included studies were also searched. A total of 537 records were identified and 392 were obtained after duplicate removal. Six records were identified after screening and three studies were included after full text eligibility assessment. Results: Three comparators were reported in the included studies: calcium hydroxide paste, 2% chlorhexidine gel and ledermix paste. There was no statistically significant difference between triple antibiotic paste and calcium hydroxide regarding postoperative pain, and clinical and radiographic healing of periapical lesions. There was no difference between triple antibiotic paste and chlorhexidine regarding flare-up incidence. However, triple antibiotic paste reduced the level of post-operative pain more than ledermix, which was statistically significant. Conclusions: The evidence is still insufficient surrounding the use of triple antibiotic paste; therefore more clinical investigations with high levels of evidence and rigorous methodologies are needed.

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Cold irrigation results in less severe pain after root canal treatment than conventional irrigation in teeth with symptomatic apical periodontitis, but the difference may be negligible after the first day

The Journal of the American Dental Association ◽

10.1016/j.adaj.2017.11.008 ◽

2018 ◽

Vol 149 (2) ◽

pp. e48 ◽

Cited By ~ 1

Author(s):

Romina Brignardello-Petersen

Keyword(s):

Root Canal ◽

Severe Pain ◽

Apical Periodontitis ◽

Root Canal Treatment ◽

The Difference ◽

Conventional Irrigation

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Management of periradicular pathosis by single visit endodontic treatment using calcium hydroxide and mineral trioxide aggregate based sealer

Update Dental College Journal ◽

10.3329/updcj.v10i2.50174 ◽

2020 ◽

Vol 10 (2) ◽

pp. 10-13

Author(s):

Md Abdul Hannan Sheikh ◽

Eyad Al Khalifa ◽

Mozammal Hossain ◽

Md Faruk Hossain ◽

Nazneen Karim ◽

...

Keyword(s):

Calcium Hydroxide ◽

Statistical Methods ◽

Root Canal ◽

Mineral Trioxide Aggregate ◽

Endodontic Treatment ◽

Root Canal Treatment ◽

Radiological Evaluation ◽

Root Canal Therapy ◽

Radiological Investigation ◽

Single Visit

In this study, 120 teeth having periradicular pathosis were treated with single visit root canal treatment and then obturated with either calcium hydroxide containing sealer or mineral trioxide aggregate based sealer. The healing of periradicular pathosis was examined at 3, 6, and 12 months by clinical and radiological evaluation. Collected data were analyzed with standard statistical methods by using SPSS version- 20. The results showed that at 3 and 6 months, the differences between calcium hydroxide containing sealer or mineral trioxide aggregate based sealer were not statistically significant. However, the healing capability of periapical radiolucency at 12 months between two groups was statistically significant (P=0.03). The final outcome of the clinical and radiological investigation showed successful results of 96.6% and 98.1% in calcium hydroxide and mineral trioxide aggregate group, respectively. In conclusion, both calcium hydroxide and mineral trioxide aggregate based sealers are almost equally effective in single visit root canal therapy for the management of periradicular pathosis. Update Dent. Coll. j: 2020; 10 (2): 10-13

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Root canal treatment with calcium hydroxide

Oral Surgery Oral Medicine Oral Pathology ◽

10.1016/0030-4220(79)90178-6 ◽

1979 ◽

Vol 47 (2) ◽

pp. 185-188 ◽

Cited By ~ 15

Author(s):

R. Holland ◽

M.J. Nery ◽

W. de Mello ◽

V. de Souza ◽

P.F.E. Bernabé ◽

...

Keyword(s):

Calcium Hydroxide ◽

Root Canal ◽

Root Canal Treatment

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Healing of a tooth with an overinstrumented apex, extensive transportation and periapical lesion using a 5 mm calcium hydroxide apical plug: an 8-year follow-up report

Brazilian Dental Journal ◽

10.1590/s0103-64402012000500024 ◽

2012 ◽

Vol 23 (5) ◽

pp. 608-611

Author(s):

Ronaldo Araújo Souza ◽

Yara T. Corrêa Silva-Sousa ◽

Suely Colombo ◽

Maurício Lago ◽

Marco Antonio Hungaro Duarte ◽

...

Keyword(s):

Calcium Hydroxide ◽

Root Canal ◽

Apical Periodontitis ◽

Filling Material ◽

Root Canal Filling ◽

Apical Constriction ◽

Gutta Percha ◽

Open Apices ◽

Canal Transportation

Besides the risk of filling material extrusion throughout the apex, a satisfactory apical seal can be difficult to achieve in canals with open apices or iatrogenic enlargements of the apical constriction. These situations pose a challenge to root canal filling. This paper describes the root canal filling of a maxillary right canine with an overinstrumented apex, complete loss of the apical stop, extensive canal transportation and apical periodontitis. A 5 mm calcium hydroxide apical plug was placed before root canal filling. The plug was made by soaking paper points with saline, dipping the points in calcium hydroxide powder and then applying it to the apex several times, until a consistent apical plug was obtained. The canal was then irrigated with saline in order to remove any residual calcium hydroxide from the root canal walls, dried with paper points and obturated with an inverted #80 gutta-percha cone and zinc oxide-eugenol based sealer by the lateral condensation technique. An 8-year radiographic follow-up showed formation of mineralized tissue sealing the apical foramen, apical remodeling and no signs of apical periodontitis.

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Effects of Contemporary Irrigant Activation Schemes and Subsequent Placement of an Interim Dressing on Bacterial Presence and Activity in Root Canals Associated with Asymptomatic Apical Periodontitis

Journal of Clinical Medicine ◽

10.3390/jcm9030854 ◽

2020 ◽

Vol 9 (3) ◽

pp. 854 ◽

Cited By ~ 7

Author(s):

Alexandre P. L. Carvalho ◽

Laura C. L. Nardello ◽

Fernanda S. Fernandes ◽

Fernanda P. Bruno ◽

Luiza R. Paz ◽

...

Keyword(s):

Calcium Hydroxide ◽

Root Canal ◽

Quantitative Polymerase Chain Reaction ◽

Apical Periodontitis ◽

Universal Primers ◽

Rrna Gene ◽

Root Canal Preparation ◽

Root Canals ◽

Mechanical Preparation ◽

Root Canal Disinfection

New tools for activating endodontic irrigants have evolved, yet their impact on root canal disinfection, in comparison to the passive placing of an inter-visit medication, have not yet been fully elucidated. The use of DNA- and rRNA-based methods may cast some new light on this issue, as they allow a comparison to be made between microbial presence and activity. Therefore, the aim of this single-arm intervention trial is to evaluate the antibacterial effect of endodontic procedures using both molecular methods. Root canal samples were obtained from 20 patients with asymptomatic apical periodontitis after each treatment step: access cavity, chemo-mechanical preparation, adjunctive procedures (XP-endo Finisher file and passive ultrasonic irrigation), calcium hydroxide medication, and 2nd-visit root canal preparation. DNA and cDNA from the samples were subjected to quantitative polymerase chain reaction with universal primers for the bacterial 16S rRNA gene. Chemo-mechanical preparation promoted a drastic reduction in bacterial levels and activity, whereas the adjunctive procedures did not make a significant contribution to further disinfection. At the 2nd visit, bacteria were active after the use of calcium hydroxide medication; however, they were significantly reduced after a 2nd-visit preparation. Consequently, the lowest bacterial levels were found at the end of the treatment. This clinical trial, which used an rRNA and rDNA combined approach, confirmed previous studies showing that root canal preparation represents the main strategy for root canal disinfection.

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