scholarly journals Three-dimensional echo-planar cine imaging of cerebral blood supply using arterial spin labeling

2016 ◽  
Vol 29 (6) ◽  
pp. 799-810 ◽  
Author(s):  
Manoj Shrestha ◽  
Toralf Mildner ◽  
Torsten Schlumm ◽  
Scott Haile Robertson ◽  
Harald Möller
Keyword(s):  
Blood Supply ◽  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Cine Imaging ◽  
Cerebral Blood Supply ◽  
Echo Planar

scholarly journals Combination of three-dimensional arterial spin labeling and stretched-exponential model in grading of gliomas

Medicine ◽  
2019 ◽  
Vol 98 (25) ◽  
pp. e16012 ◽  
Author(s):  
Yuan Qu ◽  
Lisui Zhou ◽  
Jie Jiang ◽  
Guangnan Quan ◽  
Xiaocheng Wei
Keyword(s):  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Exponential Model ◽  
Stretched Exponential ◽  
Stretched Exponential Model

scholarly journals A Combined Computational Fluid Dynamics and Arterial Spin Labeling MRI Modeling Strategy to Quantify Patient-Specific Cerebral Hemodynamics in Cerebrovascular Occlusive Disease

2021 ◽  
Vol 9 ◽  
Author(s):  
Jonas Schollenberger ◽  
Nicholas H. Osborne ◽  
Luis Hernandez-Garcia ◽  
C. Alberto Figueroa
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Supply ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Cerebral Hemodynamics ◽  
Occlusive Disease ◽  
Patient Specific ◽  
Cfd Model ◽  
Cerebrovascular Occlusive Disease

Cerebral hemodynamics in the presence of cerebrovascular occlusive disease (CVOD) are influenced by the anatomy of the intracranial arteries, the degree of stenosis, the patency of collateral pathways, and the condition of the cerebral microvasculature. Accurate characterization of cerebral hemodynamics is a challenging problem. In this work, we present a strategy to quantify cerebral hemodynamics using computational fluid dynamics (CFD) in combination with arterial spin labeling MRI (ASL). First, we calibrated patient-specific CFD outflow boundary conditions using ASL-derived flow splits in the Circle of Willis. Following, we validated the calibrated CFD model by evaluating the fractional blood supply from the main neck arteries to the vascular territories using Lagrangian particle tracking and comparing the results against vessel-selective ASL (VS-ASL). Finally, the feasibility and capability of our proposed method were demonstrated in two patients with CVOD and a healthy control subject. We showed that the calibrated CFD model accurately reproduced the fractional blood supply to the vascular territories, as obtained from VS-ASL. The two patients revealed significant differences in pressure drop over the stenosis, collateral flow, and resistance of the distal vasculature, despite similar degrees of clinical stenosis severity. Our results demonstrated the advantages of a patient-specific CFD analysis for assessing the hemodynamic impact of stenosis.

Perfusion abnormality on three-dimensional arterial spin labeling in patients with acute encephalopathy with biphasic seizures and late reduced diffusion

2020 ◽  
Vol 408 ◽  
pp. 116558 ◽  
Author(s):  
Hiroyuki Uetani ◽  
Mika Kitajima ◽  
Takeshi Sugahara ◽  
Yuichiro Muto ◽  
Katsuki Hirai ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Three Dimensional ◽  
Spin Labeling ◽  
Acute Encephalopathy ◽  
Perfusion Abnormality

scholarly journals Cerebral Blood Flow Alterations in High Myopia: An Arterial Spin Labeling Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Huihui Wang ◽  
Shanshan Li ◽  
Xi Chen ◽  
Yanling Wang ◽  
Jing Li ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
High Myopia ◽  
Brain Plasticity ◽  
Pearson Correlation ◽  
Three Dimensional ◽  
Image Data ◽  
Blood Perfusion ◽  
Spin Labeling

Objective. The aim of this study was to explore cerebral blood flow (CBF) alterations in subjects with high myopia (HM) using three-dimensional pseudocontinuous arterial spin labeling (3D-pcASL). Methods. A total of sixteen patients with bilateral HM and sixteen age- and sex-matched healthy controls (HCs) were recruited. All subjects were right-handed. Image data preprocessing was performed using SPM8 and the DPABI toolbox. Clinical parameters were acquired in the HM group. Two-sample t-tests and Pearson correlation analysis were applied in this study. Results. Compared to HCs, patients with HM exhibited significantly increased CBF in the bilateral cerebellum, and no decreases in CBF were detected in the brain. However, no relationship was found between the mean CBF values in the different brain areas and the disease duration (P>0.05). Conclusions. Using ASL analysis, we detected aberrant blood perfusion in the cerebellum in HM patients, contributing to a better understanding of brain abnormalities and brain plasticity through a different perspective.

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