Regional Variations in the Apparent and Tissue-Level Mechanical Parameters of Vertebral Trabecular Bone with Aging Using Micro-Finite Element Analysis

2007 ◽  
Vol 35 (9) ◽  
pp. 1622-1631 ◽  
Author(s):  
He Gong ◽  
Ming Zhang ◽  
Ling Qin ◽  
Yajun Hou
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Trabecular Bone ◽  
Tissue Level ◽  
Mechanical Parameters ◽  
Element Analysis ◽  
Regional Variations ◽  
Vertebral Trabecular Bone

Simulation of vertebral trabecular bone loss using voxel finite element analysis

2009 ◽  
Vol 42 (16) ◽  
pp. 2789-2796 ◽  
Author(s):  
P. Mc Donnell ◽  
N. Harrison ◽  
M.A.K. Liebschner ◽  
P.E. Mc Hugh
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Bone Loss ◽  
Trabecular Bone ◽  
Element Analysis ◽  
Vertebral Trabecular Bone ◽  
Trabecular Bone Loss

scholarly journals Spatial Correlations of Trabecular Bone Microdamage with Local Stresses and Strains Using Rigid Image Registration

2011 ◽  
Vol 133 (6) ◽  
Author(s):  
Srinidhi Nagaraja ◽  
Oskar Skrinjar ◽  
Robert E. Guldberg
Keyword(s):  
Finite Element ◽  
Image Registration ◽  
Trabecular Bone ◽  
Tissue Level ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Element Analysis ◽  
Registration Algorithm ◽  
Local Bone ◽  
Local Stresses

Although microdamage is known to accumulate in trabecular bone with overloading and aging, the tissue-level stresses and strains associated with local bone failure are not well known. Local correlation of microdamage with microstructural stresses and strains requires methods to accurately register histological sections with micro-computed tomography (micro-CT) based finite element models. In addition, the resolution of correlation (i.e., grid size) selected for analysis may affect the observed results. Therefore, an automated, repeatable, and accurate image registration algorithm was developed to determine the range of local stresses and strains associated with microdamage initiation. Using a two-dimensional rigid registration algorithm, bone structures from histology and micro-CT imaging were aligned. Once aligned, microdamaged regions were spatially correlated with local stresses and strains obtained from micro-CT based finite element analysis. Using this more sophisticated registration technique, we were able to analyze the effects of varying spatial grid resolution on local stresses and strains initiating microdamage. The results indicated that grid refinement to the individual pixel level (pixel-by-pixel method) more precisely defined the range of microdamage initiation compared to manually selected individual damaged and undamaged trabeculae. Using the pixel-by-pixel method, we confirmed that trabecular bone from younger cows sustained higher local strains prior to microdamage initiation compared to older bone.

Mechanical assessment of trabecular bone stiffness using hybrid skeleton and finite element analysis

2014 ◽  
Vol 4 (6) ◽  
pp. 352-359 ◽  
Author(s):  
Ahmad Almhdie-Imjabber ◽  
Ridha Hambli ◽  
Jérôme Touvier ◽  
Olivier Rozenbaum ◽  
Eric Lespessailles ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Trabecular Bone ◽  
Element Analysis ◽  
Bone Stiffness

scholarly journals Effects of Scan Resolutions and Element Sizes on Bovine Vertebral Mechanical Parameters from Quantitative Computed Tomography-Based Finite Element Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Meng Zhang ◽  
Jiazi Gao ◽  
Xu Huang ◽  
He Gong ◽  
Min Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Finite Element Analysis ◽  
Finite Element ◽  
Quantitative Computed Tomography ◽  
Slice Thickness ◽  
Mechanical Parameters ◽  
Ct Scanner ◽  
Computational Accuracy ◽  
Element Analysis ◽  
Vertebral Strength

Quantitative computed tomography-based finite element analysis (QCT/FEA) has been developed to predict vertebral strength. However, QCT/FEA models may be different with scan resolutions and element sizes. The aim of this study was to explore the effects of scan resolutions and element sizes on QCT/FEA outcomes. Nine bovine vertebral bodies were scanned using the clinical CT scanner and reconstructed from datasets with the two-slice thickness, that is, 0.6 mm (PA resolution) and 1 mm (PB resolution). There were significantly linear correlations between the predicted and measured principal strains (R2>0.7, P<0.0001), and the predicted vertebral strength and stiffness were modestly correlated with the experimental values (R2>0.6, P<0.05). Two different resolutions and six different element sizes were combined in pairs, and finite element (FE) models of bovine vertebral cancellous bones in the 12 cases were obtained. It showed that the mechanical parameters of FE models with the PB resolution were similar to those with the PA resolution. The computational accuracy of FE models with the element sizes of 0.41 × 0.41 × 0.6 mm3 and 0.41 × 0.41 × 1 mm3 was higher by comparing the apparent elastic modulus and yield strength. Therefore, scan resolution and element size should be chosen optimally to improve the accuracy of QCT/FEA.

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