Social Support and the Mediating Roles of Alcohol Use and Adherence Self-Efficacy on Antiretroviral Therapy (ART) Adherence Among ART Recipients in Gauteng, South Africa

2016 ◽  
Vol 21 (7) ◽  
pp. 1846-1856 ◽  
Author(s):  
Connie T. Kekwaletswe ◽  
Esmé Jordaan ◽  
Sebenzile Nkosi ◽  
Neo K. Morojele
2021 ◽  
Author(s):  
Jeroen De Man ◽  
Francis Xavier Kasujja ◽  
Peter Delobelle ◽  
Kristi Sidney Annerstedt ◽  
Helle Mölsted Alvesson ◽  
...  

Abstract BackgroundUnderstanding motivational determinants of physical activity (PA) is essential to guide the implementation of PA at individual and population level. Knowledge about the cross-cultural generalizability of these determinants is lacking and they have mostly been studied as separate factors. This study compares a motivational process model across samples from diverse populations with, or at risk of diabetes. MethodsMeasurement invariance of barrier identified regulation, barrier self-efficacy and social support was assessed in a rural Ugandan sample (n=712) and disadvantaged samples with high proportions of immigrants in urban South Africa (n=566) and Sweden (n=147). These motivational determinants were then compared through multigroup structural equation modeling.ResultsThe studied motivational constructs showed scalar invariance. Latent mean levels of perceived social support and barrier self-efficacy were lower in South Africa and Sweden. Structural models (for different PA outcomes) were not consistent across settings except for the association between perceived social support and identified regulation. Identified regulation was only associated with vigorous PA in Uganda and with moderate PA in South Africa. The association between social support and PA outcomes ranged from weak to not significant and the association between self-efficacy and PA was not significant. Self-reported PA was highest in Uganda and lowest in Sweden. Self-reported vigorous PA was significantly related to lower hemoglobin A1c levels, while moderate PA was not.ConclusionsFindings suggest that: 1) it is feasible to compare a motivational process model across diverse settings; 2) there is lower perceived social support and self-efficacy in the urban, migrant samples; 3) identified regulation is a more promising determinant of PA than self-efficacy or social support in these populations; 4) associations between motivational determinants and PA depend on the perceived type and/or intensity of PA; 5) perceived relatedness functions as a basic psychological need across diverse settings; and 6) people’s perception of the PA they perform depends on their perceived level of intensity of PA which would have major implications for health promotion.


2016 ◽  
Vol 20 (1) ◽  
pp. 149-159 ◽  
Author(s):  
Marcia Wong ◽  
Landon Myer ◽  
Allison Zerbe ◽  
Tamsin Phillips ◽  
Greg Petro ◽  
...  

2016 ◽  
Vol 22 (11) ◽  
pp. 1426-1433 ◽  
Author(s):  
Jessica F Magidson ◽  
Wylene Saal ◽  
Adriaan Nel ◽  
Jocelyn E Remmert ◽  
Ashraf Kagee

Despite the prevalence of depression and alcohol use among HIV-infected individuals, few studies have examined their association together in relation to nonadherence to antiretroviral therapy in sub-Saharan Africa. This study examined depressive symptoms, alcohol use, and other psychosocial factors (stigma, demographic characteristics) in relation to nonadherence to antiretroviral therapy among clinic-attending, HIV-infected individuals in South Africa ( n = 101). Nonadherence was assessed using event-level measurement (missed doses over the past weekend). Multivariable logistic regression analyses revealed that only alcohol use, over and above depressive symptoms and education level, was associated with antiretroviral therapy nonadherence(AOR = 1.15; 95%CI = 1.02–1.29; p < .05). Findings point to the independent association of alcohol use and nonadherence to antiretroviral therapy above and beyond depressive symptoms.


2021 ◽  
Author(s):  
Kenneth Kalani ◽  
Janet Nakigudde ◽  
Caroline Birungi ◽  
Joy Gumikiriza- Onoria ◽  
Nelson Mukiza ◽  
...  

Abstract Background Alcohol use disorder (AUD) is a problem globally and Uganda has one of the highest per capita alcohol consumption rates in sub-Saharan Africa. Relapse is a distressing aspect in the treatment of AUD and it is mediated by self-efficacy and perceived social support besides other psychosocial factors. In Uganda, there is paucity of data regarding relapse of AUD and the association with self-efficacy and perceived social support hence the need to carry out this study. Objective To determine the prevalence of relapse of AUD and the association with self-efficacy and perceived social support at Butabika hospital. Methods A cross-sectional study design was used and 269 participants that received treatment for AUD at hospital in the period between 1st /01/2016 and 31st /12/2017 were consecutively recruited. Participants were assessed for relapse of AUD using the SCID-5 substance use disorder section. Data was collected using a socio-demographic questionnaire, the general self-efficacy scale and the multidimensional scale for perceived social support. Data was entered in Epidata 3.0 and imported into STATA version 14 for analysis. Chi square test and logistic regression were used at bi-variable and multivariable analysis respectively to determine associations. Results The prevalence of relapse of AUD among the 269 participants was 63.3% (170). Of those who relapsed, 98% (167) had severe AUD. Participants with a marital status of single were less likely to relapse into alcohol use than those with a marital status of; separated or divorced (OR = 6.81; 95% CI = 1.53–30.32; p-value = 0.012) and married (OR = 2.86; 95% CI = 1.07–7.65; p-value = 0.037). Male participants were more likely to relapse into AUD than the females (OR = 0.19; 95%CI = 0.04–0.86; p-value = 0.03). Participants with higher perceived social support (OR = 0.85; 95% CI = 0.81–0.9; p-value = < 0.001) were less likely to relapse into AUD. Self-efficacy (OR = 0.93; 95% CI = 0.85-1; p-value = 0.061) was not significantly associated with relapse of AUD. Conclusion The prevalence of relapse of AUD is high and is associated with perceived social support, marital status of; separated, divorced or married, and female gender. Relapse prevention programs should emphasize the importance of social support in the management of patients with AUD. Further research to assess the relationship between relapse of AUD among married people is recommended.


2019 ◽  
Vol 11 (11) ◽  
pp. 141
Author(s):  
Bulelwa Frieda Mayeye ◽  
Daniel Ter Goon ◽  
Elizabeth Matise Yako

It is important to understand the factors affecting willingness of adolescents and youths to adhere to antiretroviral therapy (ART) in order to ensure positive treatment outcomes. Drawing on the Health Belief Model (HBM) theory, this study investigated the influence of self-efficacy and perceived benefits on the adherence to ART medications among adolescents and youths in Buffalo City Metropolitan Municipality (BCMM) District, Eastern Cape, South Africa. A purposive sample of 206 HIV positive adolescents and youth between age 14 to 24 years receiving ART in Buffalo City Metropolitan Municipality were interviewed using a self- administered questionnaire covering treatment benefits and self-efficacy. The majority of the participants affirmed strict adherence to the treatment plan is essential for effective ARV treatment (69.4%). The participants always take their medication on schedule (88.8%). It was found that a significant relationship exists between self-efficacy and adherence to ART (p = 0.000). The results suggest that perceived benefits and self-efficacy are a predictor of adherence to ART by adolescents and youths, at least in this setting.


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242817
Author(s):  
Jessica E. Long ◽  
Barbra A. Richardson ◽  
George Wanje ◽  
Kate S. Wilson ◽  
Juma Shafi ◽  
...  

Background Excessive alcohol intake has been associated with poor adherence to antiretroviral therapy (ART). The impact of alcohol on viral suppression is particularly important among groups at high risk of HIV transmission, such as female sex workers (FSWs). Few studies have directly evaluated the association between alcohol use and HIV viral load. We hypothesized that hazardous or harmful alcohol use is associated with detectable plasma viral load among HIV-positive FSWs. Methods A prospective cohort study was conducted among HIV-positive FSWs in Mombasa, Kenya. Hazardous or harmful alcohol use was assessed yearly and defined as an Alcohol Use Disorders Identification Test (AUDIT) score ≥7. Detectable viral load was assessed every six months and defined as ≥180 c/mL. Adherence measures were collected monthly and included late ART refill (>48 hours) and self-reported adherence, using both a validated self-rating scale of ability to take medication and visual analog scale (VAS) of ART use in the last month. Generalized estimating equations were used to estimate adjusted relative risks (aRR) and 95% confidence intervals (CI). Results This analysis included 366 participants followed monthly between October 2012 and March 2018. At baseline, AUDIT scores indicated hazardous alcohol use (AUDIT 7–15) in 14.3%, harmful alcohol use (AUDIT 16–19) in 1.4%, and alcohol dependency (AUDIT ≥20) in 1.4% of participants. After adjusting for potential confounders, a combined exposure including hazardous, harmful, and dependent alcohol use was not associated with detectable viral load (aRR 1.10, 95%CI 0.63–1.92) or late ART refill (aRR 1.13, 95%CI 0.82–1.56), but was associated with lower self-rated ability to take medication (aRR 2.38, 95%CI 1.42–3.99) and a lower rate of self-reported perfect ART adherence by VAS (aRR 2.62, 95%CI 1.84–3.71). Conclusions In this FSW cohort, while participants reporting hazardous, harmful, or dependent alcohol use were not more likely to have a detectable viral load, they were more likely to report lower ART adherence. These results suggest that interventions targeting alcohol use among this population of FSWs may not have a large impact on viral suppression.


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