scholarly journals Correlates of Serodiscordant Condomless Anal Intercourse Among Virologically Detectable HIV-Positive Young Men Who Have Sex with Men

2018 ◽  
Vol 22 (11) ◽  
pp. 3535-3539 ◽  
Author(s):  
Douglas Bruce ◽  
◽  
José A. Bauermeister ◽  
Shoshana Y. Kahana ◽  
Eduardo Mendoza ◽  
...  
2020 ◽  
Vol 66 (6) ◽  
pp. 672-683 ◽  
Author(s):  
Lisa Hightow-Weidman ◽  
Kate Muessig ◽  
Joseph R. Egger ◽  
Sara LeGrand ◽  
Alyssa Platt

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Patrizia Künzler-Heule ◽  
◽  
Sandra Engberg ◽  
Manuel Battegay ◽  
Axel J. Schmidt ◽  
...  

Abstract Background Hepatitis C virus (HCV) is common in men who have sex with men (MSM) with HIV. The Swiss HCVree Trial targeted a micro-elimination by using a treat and counsel strategy. Self-reported condomless anal intercourse with non-steady partners was used as the selection criterion for participation in a counselling intervention designed to prevent HCV re-infection. The purpose of this study was to assess the ability of this criterion to identify men who engaged in other sexual risk behaviours associated with HCV re-infection. Methods Men who disclosed their sexual and drug- use behaviours during the prior 6 months, at study baseline, were included in the current study. Using a descriptive comparative study design, we explored self-reported sexual and drug-use risk behaviours, compared the odds of reporting each behaviour in men who reported and denied condomless anal intercourse with non-steady partners during the prior year and calculated the sensitivity/specificity (95% CI) of the screening question in relation to the other at-risk behaviours. Results Seventy-two (61%) of the 118 men meeting eligibity criteria reported condomless anal intercourse with non-steady partners during the prior year. Many also engaged in other potential HCV transmission risk behaviours, e.g., 52 (44%) had used drugs. In participants disclosing drug use, 44 (37%) reported sexualised drug use and 17 (14%) injected drugs. Unadjusted odds ratios (95% CI) for two well-known risk behaviours were 2.02 (0.80, 5.62) for fisting and 5.66 (1.49, 37.12) for injecting drug use. The odds ratio for sexualised drug use - a potential mediator for increased sexual risk taking - was 5.90 (2.44, 16.05). Condomless anal intercourse with non-steady partners showed varying sensitivity in relation to the other risk behaviours examined (66.7–88.2%). Conclusions Although condomless anal intercourse with non-steady partners was fairly sensitive in detecting other HCV relevant risk behaviours, using it as the only screening criterion could lead to missing a proportion of HIV-positive men at risk for HCV re-infection due to other behaviours. This work also points to the importance of providing access to behavioral interventions addressing other sexual and drug use practices as part of HCV treatment. Trial registration Clinical Trial Number: NCT02785666, 30.05.2016.


2018 ◽  
Vol 95 (2) ◽  
pp. 108-114
Author(s):  
Nicole Theresa Burton ◽  
Kavita Misra ◽  
Angelica Bocour ◽  
Sharmila Shah ◽  
Rodolfo Gutierrez ◽  
...  

ObjectivesCondomless anal intercourse contributes significantly to the spread of HIV among men who have sex with men (MSM). Factors related to condomless anal intercourse with known HIV-positive partners among MSM are not well understood. The authors describe factors associated with inconsistent condom use with known HIV-positive partners prior to participants’ diagnosis with HIV.MethodsNew York City health department disease intervention specialists interviewed newly HIV-diagnosed MSM ages ≥13 years reporting knowingly having anal sex with HIV-positive partners between June 2013 and October 2014. Univariate and bivariate statistics were calculated, in addition to logistic regression analysis.ResultsAmong 95 MSM interviewed, 56% were >30 years and 74% had higher than a high school education. Respondents reported a median of 2 known HIV-positive sex partners. Drug or alcohol use during last sex with their last known HIV-positive partner was reported by 53% of participants. Sixty-five per cent of participants reported inconsistent condom use with last known HIV-positive partner. Inconsistent condom use with all HIV-positive partners was higher among individuals reporting two or more known HIV-positive partners since sexual debut than among those with one (90% vs 59%, p<0.01) and among those reporting feelings of love/emotional attachment as a reason for having sex (85% vs 63%, p=0.02). In the bivariate logistic regression models for inconsistent condom use, feelings of love or emotional attachment were the only significant predictor of inconsistent condom use (OR 3.43, 95%  CI 1.23 to 9.58). After adjusting for confounding, the relationship feelings of love or emotional attachment continued to be the only significant predictor of inconsistent condom use (OR 3.69, 95%  CI 1.06 to 12.82).ConclusionsSurveyed MSM engaged in high-risk behaviours, including condomless anal sex and drug or alcohol use during sex with persons known to be HIV-positive. These findings can inform interventions with MSM in serodiscordant partnerships.


2014 ◽  
Vol 41 (12) ◽  
pp. 749-755 ◽  
Author(s):  
Andrew D. Margolis ◽  
Heather Joseph ◽  
Sabina Hirshfield ◽  
Mary Ann Chiasson ◽  
Lisa Belcher ◽  
...  

2019 ◽  
Vol 30 (4) ◽  
pp. 405-414 ◽  
Author(s):  
Salem Harry-Hernández ◽  
Su Hyun Park ◽  
Kenneth H. Mayer ◽  
Noah Kreski ◽  
William C. Goedel ◽  
...  

Sexual Health ◽  
2018 ◽  
Vol 15 (4) ◽  
pp. 370 ◽  
Author(s):  
H. Rhodes Hambrick ◽  
Su Hyun Park ◽  
Joseph J. Palamar ◽  
Anthony Estreet ◽  
John A. Schneider ◽  
...  

The use of inhaled nitrites, or poppers, among men who have sex with men (MSM) is prevalent, yet has been associated with HIV seroconversion. We surveyed 580 MSM from a geosocial networking smartphone application in Paris, France, in 2016. Of the respondents, 46.7% reported popper use within the previous 3 months. Regression models adjusted for sociodemographic characteristics found that the use of poppers was significantly (P < 0.05) associated with the following during the prior 3 months: condomless anal intercourse (adjusted relative risk (aRR) 1.27, 95% confidence interval (CI) 1.07–1.50), use of alcohol and/or drugs during sex once or twice (adjusted relative risk ratio (aRRR) 2.33, 95% CI 1.44–2.03), three to five times (aRRR 5.41, 95% CI 2.98–9.84) or six or more times (aRRR 4.09, 95% CI 2.22–7.56), participation in group sex (aRRR 3.70, 95% CI 2.33–5.90) and self-reported diagnosis with any sexually transmissible infection over the previous year (aRR 1.63, 95% CI 1.18–2.27), specifically chlamydia (aRR 2.75, 95% CI 1.29–4.29) and syphilis (aRR 2.27, 95% CI 1.29–4.29).


2019 ◽  
Vol 71 (3) ◽  
pp. 574-582 ◽  
Author(s):  
David P Serota ◽  
Eli S Rosenberg ◽  
Patrick S Sullivan ◽  
Annie L Thorne ◽  
Charlotte-Paige M Rolle ◽  
...  

Abstract Background Human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) has great potential to reduce HIV incidence among young black men who have sex with men (YBMSM); however, initiation and persistence for this group remain low. We sought to understand the patterns and predictors of PrEP uptake and discontinuation among YBMSM in Atlanta, Georgia. Methods PrEP was offered to all participants in a prospective cohort of YBMSM aged 18–29 years not living with HIV. Time to PrEP uptake, first discontinuation, and final discontinuation were assessed using the Kaplan-Meier method. Cox proportional hazard models were used to identify predictors of uptake and discontinuation. Results After 440 person-years of follow-up, 44% of YBMSM initiated PrEP through the study after a median of 122 days. Of PrEP initiators, 69% had a first discontinuation and 40% had a final discontinuation during the study period. The median time to first PrEP discontinuation was 159 days. Factors associated with PrEP uptake included higher self-efficacy, sexually transmitted infection (STI), and condomless anal intercourse. Factors associated with discontinuation included younger age, cannabis use, STI, and fewer sex partners. HIV incidence was 5.23/100 person-years (95% confidence interval [CI], 3.40–7.23), with a lower rate among those who started PrEP (incidence rate ratio, 0.39; 95% CI, .16–.92). Conclusions Persistent PrEP coverage in this cohort of YBMSM was suboptimal, and discontinuations were common despite additional support services available through the study. Interventions to support PrEP uptake and persistence, especially for younger and substance-using YBMSM, are necessary to achieve full PrEP effectiveness. Clinical Trials Registration NCT02503618.


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