Discovery of novel inhibitors for human intestinal maltase: virtual screening in a WISDOM environment and in vitro evaluation

2011 ◽  
Vol 33 (11) ◽  
pp. 2185-2191 ◽  
Author(s):  
Thi Thanh Hanh Nguyen ◽  
Hwa-Ja Ryu ◽  
Se-Hoon Lee ◽  
Soonwook Hwang ◽  
Jaeho Cha ◽  
...  
Keyword(s):  
Virtual Screening ◽  
In Vitro Evaluation ◽  
Human Intestinal Maltase

Identification of novel inhibitors of HCV RNA-dependent RNA polymerase by pharmacophore-based virtual screening and in vitro evaluation

2009 ◽  
Vol 17 (8) ◽  
pp. 2975-2982 ◽  
Author(s):  
Kisun Ryu ◽  
Nam Doo Kim ◽  
Seong Il Choi ◽  
Cheol Kyu Han ◽  
Jeong Hyeok Yoon ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Rna Polymerase ◽  
Hcv Rna ◽  
Rna Dependent Rna Polymerase ◽  
In Vitro Evaluation

scholarly journals A Novel Inhibitor of Human La Protein with Anti-HBV Activity Discovered by Structure-Based Virtual Screening and In Vitro Evaluation

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e36363 ◽  
Author(s):  
Jing Tang ◽  
Zhi-Min Huang ◽  
Ying-Yi Chen ◽  
Zhao-Hui Zhang ◽  
Gao-Lin Liu ◽  
...  
Keyword(s):  
Virtual Screening ◽  
In Vitro Evaluation ◽  
La Protein

scholarly journals VIRTUAL SCREENING OF STILBENE ANALOGUE AND INSILICO, IN VITRO ANTIPROTOZOAL EVALUATION OF LEAD MOLECULES

2017 ◽  
pp. 97-99
Author(s):  
G. Lalasa ◽  
S. Vijayaraj ◽  
K. Thamizhvanan ◽  
K. Chaithanyaveena
Keyword(s):  
Virtual Screening ◽  
In Silico ◽  
In Silico Analysis ◽  
Binding Energies ◽  
Antiprotozoal Activity ◽  
In Vitro Evaluation ◽  
Stilbene Analogues ◽  
Silico Analysis ◽  
Arginase I

Objective: The objective of present study is the virtual screening of stilbene analogues followed by the in silico and in vitro evaluation for its anti protozoal activity.Methods: The method of virtual screening selected is the structure-based virtual screening using ChEMBL database. The in silico analysis was performed using auto dock tools 4.2. The docking was performed using 1T5F (Arginase I-OH complex) as the binding proteins which are drawn from the protein data bank.Results: The stilbene analogues from virtual screening are allowed to dock with the proteins the binding energies and docking positions were determined using auto dock tools 4.2. The in vitro evaluation of anti protozoal activity was performed.Conclusion: The stilbene analogues are capable of producing the antiprotozoal activity.

In vitro evaluation of IL-18 effects in Crohn's disease

2001 ◽  
Vol 120 (5) ◽  
pp. A316-A317
Author(s):  
P MAERTEN ◽  
S COLPAERT ◽  
Z LIU ◽  
K GEBOES ◽  
J CEUPPENS ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
In Vitro Evaluation

52: In Vitro Evaluation of Ureteral Stent Compression

2006 ◽  
Vol 175 (4S) ◽  
pp. 18-18
Author(s):  
Kari Hendlin ◽  
Krishna Vedula ◽  
Christina Horn ◽  
Manoj Monga
Keyword(s):  
Ureteral Stent ◽  
In Vitro Evaluation
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