scholarly journals Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients

2009 ◽  
Vol 119 (2) ◽  
pp. 367-377 ◽  
Author(s):  
K. Hancke ◽  
D. Grubeck ◽  
N. Hauser ◽  
R. Kreienberg ◽  
J. M. Weiss
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Prognostic Factor ◽  
Cancer Patients ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Breast Cancer Patients ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Overexpression of fatty acid binding protein-7 correlates with basal-like subtype of breast cancer

2010 ◽  
Vol 206 (2) ◽  
pp. 98-101 ◽  
Author(s):  
Xiao Yan Tang ◽  
Shinobu Umemura ◽  
Hideo Tsukamoto ◽  
Nobue Kumaki ◽  
Yutaka Tokuda ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Masahiro Kawashima ◽  
Karim Bensaad ◽  
Christos E. Zois ◽  
Alessandro Barberis ◽  
Esther Bridges ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Beige Fat

Heart-type fatty acid–binding protein as a prognostic factor in patients with severe sepsis and septic shock

2012 ◽  
Vol 30 (9) ◽  
pp. 1749-1755 ◽  
Author(s):  
You Hwan Jo ◽  
Kyuseok Kim ◽  
Jae Hyuk Lee ◽  
Joong Eui Rhee ◽  
Jin Hee Lee ◽  
...  
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Fatty Acid ◽  
Prognostic Factor ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Sepsis And Septic Shock

Abstract 3563: Fatty acid binding protein 7 regulates beige fat-like differentiation of breast cancer cells and thermogenesis

2020 ◽  
Author(s):  
Masahiro Kawashima ◽  
Karim Bensaad ◽  
Christos Zois ◽  
Alessandro Barberis ◽  
Esther Bridges ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Beige Fat

scholarly journals Differential expression of fatty acid binding protein 4 in cancers of the breast.

2021 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Differential Expression ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Normal Breast ◽  
Differentially Expressed ◽  
Primary Tumors ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding fatty acid binding protein 4, FABP4, when comparing primary tumors of the breast to the tissue of origin, the normal breast. FABP4 mRNA was present at significantly lower quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of FABP4 in primary tumors of the breast was correlated with recurrence-free survival in patients with HER2+ cancers, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by molecular subtype. FABP4 may be of relevance to initiation, maintenance or progression of cancers of the female breast.

Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer

2012 ◽  
Vol 134 (2) ◽  
pp. 519-529 ◽  
Author(s):  
Alaa T. Alshareeda ◽  
Emad A. Rakha ◽  
Christopher C. Nolan ◽  
Ian O. Ellis ◽  
Andrew R. Green
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Cellular Localization ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Dynamic Changes of Serum Heart Type-Fatty Acid Binding Protein in Cancer Patients Treated With Immune Checkpoint Inhibitors

2021 ◽  
Vol 12 ◽  
Author(s):  
Ming Yuan ◽  
Li Zang ◽  
Aiqing Xu ◽  
Mengqi Gong ◽  
Qing Liu ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Fatty Acid ◽  
Cancer Patients ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
Fatty Acid Binding Protein ◽  
Checkpoint Inhibitors ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Objective: Immune checkpoint inhibitors (ICIs) are effective anti-cancer drugs that can improve survival in cancer patients, but their use may be associated with adverse cardiovascular side effects. Therefore, there is a clinical unmet need to identify non-invasive biomarker to detect subclinical cardiac toxicity after ICI treatment. The aim of this study is to examine the plasma levels of biomarkers in cancer survivors who were treated with ICIs.Patients and Methods: In a cohort of 19 cancer patients, biomarkers were evaluated at baseline, 1 month, 3 and 6 months after ICI administration. These biomarkers, hypothesized to be mechanistically relevant to cardiotoxicity, included cardiac troponin I (cTnI), high-sensitivity C-reactive protein (Hs-CRP), N-terminal pro–B-type natriuretic peptide (NT-pro BNP), CK (creatine kinase), CK-MB (creatine kinase-MB), Pentraxin-related protein 3 (PTX3), growth differentiation factor 15 (GDF-15), heart type-fatty acid binding protein (H-FABP) and galectin 3 (Gal-3).Results: H-FABP, but not other biomarkers, were increased at 3 months, which persisted at 6 months (529.28 ± 312.83 vs. 752.33 ± 283.65 vs. 808.00 ± 289.69 pg/ml, p = 0.031 and p = 0.013). Left ventricular ejection fraction (63.00 ± 4.15% vs. 63.74 ± 4.07%, p > 0.05) was not significantly reduced at this time point.Conclusions: H-FABP, but not other biomarkers, were increased in patients who were treated using ICIs. H-FABP might be a more sensitive biomarker to detect ICI-related subclinical myocardial damage than traditional cardiac biomarkers.

scholarly journals Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Masahiro Kawashima ◽  
Karim Bensaad ◽  
Christos E. Zois ◽  
Alessandro Barberis ◽  
Esther Bridges ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Beige Fat
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