Lipoprotein-Associated and Secretory Phospholipase A2 in Cardiovascular Disease: The Epidemiological Evidence

2008 ◽  
Vol 23 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Wolfgang Koenig ◽  
Natalie Khuseyinova
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Secretory Phospholipase A2 ◽  
Epidemiological Evidence ◽  
Secretory Phospholipase

scholarly journals Secretory Phospholipase A2-IIA and Cardiovascular Disease

2013 ◽  
Vol 62 (21) ◽  
pp. 1966-1976 ◽  
Author(s):  
Michael V. Holmes ◽  
Tabassome Simon ◽  
Holly J. Exeter ◽  
Lasse Folkersen ◽  
Folkert W. Asselbergs ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase

scholarly journals Secretory Phospholipase A2 Tipe II (SPLA II) In Cardiovascular Disease

2015 ◽  
pp. 162-70
Author(s):  
Djanggan Sargowo
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Inflammatory Mediator ◽  
Recent Literature ◽  
Acute Phase Reactant ◽  
Multiple Roles ◽  
Secretory Phospholipase A2 ◽  
Inflammatory Reactions ◽  
Secretory Phospholipase

Inflammatory reactions contribute to the pathogenesis of cardiovascular conditions such as atherosclerosis and ischemic damage in acute myocardial infarction (AMI). Among the mediators involved in inflammation are secretory phospholipase A2 group II (sPLA2-II) enzymes. Though some cells constitutively express Spla2-II, the synthesis by cells such as hepatocytes is typical for an acute-phase reactant. Recent literature suggest multiple roles for sPLA2-II in cardiovascular disease. In this review we discuss the role of sPLA2-II in included that sPLA2-II appears to be an inportant inflammatory mediator of cardiovascular disease.

scholarly journals HDL modification by secretory phospholipase A2 promotes scavenger receptor class B type I interaction and accelerates HDL catabolism

2000 ◽  
Vol 41 (11) ◽  
pp. 1849-1857 ◽  
Author(s):  
Frederick C. de Beer ◽  
Patrice M. Connell ◽  
J. Yu ◽  
Maria C. de Beer ◽  
Nancy R. Webb ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Scavenger Receptor ◽  
Type I ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase ◽  
Scavenger Receptor Class ◽  
Class B
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