scholarly journals Limits of Mendelian Randomization Analyses in Selection of Secretory Phospholipase A2-IIA as a Valid Therapeutic Target for Prevention of Cardiovascular Disease

2014 ◽  
Vol 63 (9) ◽  
pp. 942-943 ◽  
Author(s):  
Robert S. Rosenson ◽  
Eva Hurt-Camejo
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Therapeutic Target ◽  
Mendelian Randomization ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase ◽  
Prevention Of Cardiovascular Disease ◽  
Selection Of

scholarly journals Secretory Phospholipase A2-IIA and Cardiovascular Disease

2013 ◽  
Vol 62 (21) ◽  
pp. 1966-1976 ◽  
Author(s):  
Michael V. Holmes ◽  
Tabassome Simon ◽  
Holly J. Exeter ◽  
Lasse Folkersen ◽  
Folkert W. Asselbergs ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase

scholarly journals Secretory Phospholipase A2 Tipe II (SPLA II) In Cardiovascular Disease

2015 ◽  
pp. 162-70
Author(s):  
Djanggan Sargowo
Keyword(s):  
Cardiovascular Disease ◽  
Phospholipase A2 ◽  
Inflammatory Mediator ◽  
Recent Literature ◽  
Acute Phase Reactant ◽  
Multiple Roles ◽  
Secretory Phospholipase A2 ◽  
Inflammatory Reactions ◽  
Secretory Phospholipase

Inflammatory reactions contribute to the pathogenesis of cardiovascular conditions such as atherosclerosis and ischemic damage in acute myocardial infarction (AMI). Among the mediators involved in inflammation are secretory phospholipase A2 group II (sPLA2-II) enzymes. Though some cells constitutively express Spla2-II, the synthesis by cells such as hepatocytes is typical for an acute-phase reactant. Recent literature suggest multiple roles for sPLA2-II in cardiovascular disease. In this review we discuss the role of sPLA2-II in included that sPLA2-II appears to be an inportant inflammatory mediator of cardiovascular disease.

scholarly journals Type II Secretory Phospholipase A2 and Prognosis in Patients with Stable Coronary Heart Disease: Mendelian Randomization Study

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e22318 ◽  
Author(s):  
Lutz P. Breitling ◽  
Wolfgang Koenig ◽  
Marcus Fischer ◽  
Ziad Mallat ◽  
Christian Hengstenberg ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Phospholipase A2 ◽  
Mendelian Randomization ◽  
Type Ii ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase ◽  
Stable Coronary Heart Disease

scholarly journals HDL modification by secretory phospholipase A2 promotes scavenger receptor class B type I interaction and accelerates HDL catabolism

2000 ◽  
Vol 41 (11) ◽  
pp. 1849-1857 ◽  
Author(s):  
Frederick C. de Beer ◽  
Patrice M. Connell ◽  
J. Yu ◽  
Maria C. de Beer ◽  
Nancy R. Webb ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Scavenger Receptor ◽  
Type I ◽  
Secretory Phospholipase A2 ◽  
Secretory Phospholipase ◽  
Scavenger Receptor Class ◽  
Class B
Sign in / Sign up

Export Citation Format

Share Document