Protective Role of Lithium in Ameliorating the Aluminium-induced Oxidative Stress and Histological Changes in Rat Brain

2009 ◽  
Vol 29 (4) ◽  
pp. 513-521 ◽  
Author(s):  
Punita Bhalla ◽  
D. K. Dhawan
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Protective Role ◽  
Histological Changes

Protective Role of Gallic Acid on Sodium Fluoride Induced Oxidative Stress in Rat Brain

2012 ◽  
Vol 89 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Seyed Fazel Nabavi ◽  
Solomon Habtemariam ◽  
Mahtab Jafari ◽  
Antoni Sureda ◽  
Seyed Mohammad Nabavi
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Gallic Acid ◽  
Sodium Fluoride ◽  
Protective Role

scholarly journals Protective role of Telfairia occidentalis in irradiation-induced oxidative stress in rat brain

2014 ◽  
Vol 8 (3) ◽  
pp. 843 ◽  
Author(s):  
SA Adejuwon ◽  
IO Imosemi ◽  
PA Ebokaiwe ◽  
JO Omirinde ◽  
AA Adenipekun
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Protective Role ◽  
Telfairia Occidentalis

Protective role of zinc in ameliorating the arsenic-induced oxidative stress and histological changes in rat liver

2009 ◽  
Vol 189 ◽  
pp. S206
Author(s):  
Ashok Kumar ◽  
Mohan Lal Garg ◽  
Shaoli Majumdar ◽  
Davinder Kumar Dhawan
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Protective Role ◽  
Histological Changes

scholarly journals Protective role of maize purple plant pigment against oxidative stress in fluorosis rat brain

2020 ◽  
Vol 11 (1) ◽  
pp. 89-95
Author(s):  
Boyan Li ◽  
Keyana Nozzari Varkani ◽  
Lu Sun ◽  
Bo Zhou ◽  
Xiaohong Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Damage ◽  
Rat Brain ◽  
Neuronal Apoptosis ◽  
Protective Role ◽  
Fluoride Toxicity ◽  
Plant Pigment

AbstractIn fluorosis-endemic areas, exposure to high levels of fluoride causes neurotoxicity such as lowered intelligence and cognitive impairment. Oxidative damage is critical to pathophysiologic processes of fluoride intoxication, and neurotoxicity of fluoride may be associated with oxidative stress. In previous studies, maize purple plant pigment (MPPP), which was rich in anthocyanins, showed a strong scavenging activity in vitro and in vivo. The present study aimed to determine whether treatment with MPPP can alleviate fluoride-induced oxidative damage in rat brain. After 3 months of experiment, brain tissues were assayed for oxidative stress variables, histological and Western blotting examinations. Our results showed that MPPP reduced the elevated malondialdehyde levels, increased superoxide dismutase activity, and further attenuated histopathological alterations and mitigated neuronal apoptosis. Importantly, MPPP also reversed changes in Bax and Bcl-2. Therefore, it was speculated that MPPP protects brain tissue from fluoride toxicity through its antioxidant capacity.

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