Serum Procalcitonin Levels are Associated with Clinical Outcome in Intracerebral Hemorrhage

2017 ◽  
Vol 38 (3) ◽  
pp. 727-733 ◽  
Author(s):  
Dingxiu He ◽  
Yun Zhang ◽  
Biao Zhang ◽  
Wei Jian ◽  
Xiaojian Deng ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Intracerebral Hemorrhage

scholarly journals Association of Molecular Markers With Perihematomal Edema and Clinical Outcome in Intracerebral Hemorrhage

Stroke ◽  
2013 ◽  
Vol 44 (3) ◽  
pp. 658-663 ◽  
Author(s):  
Na Li ◽  
Yan Fang Liu ◽  
Li Ma ◽  
Hans Worthmann ◽  
Yi Long Wang ◽  
...  
Keyword(s):  
Molecular Markers ◽  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
Perihematomal Edema

Association between Apolipoprotein E Polymorphism and Clinical Outcome after Ischemic Stroke, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage

2021 ◽  
pp. 1-10
Author(s):  
Wen Pan ◽  
Min Zhang ◽  
Zhenping Guo ◽  
Wenfeng Xiao ◽  
Chao You ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Subarachnoid Hemorrhage ◽  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
Apolipoprotein E ◽  
Functional Outcomes ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Fixed Effects Models ◽  
Increased Risk

<b><i>Backgrounds:</i></b> Previous studies reported inconsistent results regarding associations between apolipoprotein E (<i>APOE</i>) polymorphism and clinical outcomes after ischemic stroke (IS), intracerebral hemorrhage (ICH), or subarachnoid hemorrhage (SAH). Thus, the study was designed to make a systematic review and meta-analysis regarding the association between <i>APOE</i> polymorphism and clinical outcome after IS, ICH, and SAH. <b><i>Methods:</i></b> To identify studies eligible for this meta-analysis, we searched for articles published before August 2021 in the databases (PubMed, Web of Science, and Google Scholar). We used STATA 12.0 software to compute hazard ratios (HRs) and their 95% confidence intervals (CIs) regarding <i>APOE</i> polymorphism and clinical outcome after IS, ICH, and SAH. <b><i>Results:</i></b> Meta-analysis showed no significant association between <i>APOE</i> polymorphism and functional outcome after IS with fixed effects models (ε4 carrier vs. non-ε4 carrier: HR, 1.00; 95% CI: 0.83–1.21, <i>I</i><sup>2</sup> = 29.4%, <i>p</i> = 0.183; ε2 carrier vs. non-ε2 carrier: HR, 0.92; 95% CI: 0.72–1.16, <i>I</i><sup>2</sup> = 15.6%, <i>p</i> = 0.307). Meta-analysis showed that ICH patients carrying ε4 allele have increased risk of poor outcome in Caucasian population with fixed effects models (ε4 carrier vs. non-ε4 carrier: HR, 1.75; 95% CI: 1.19–2.57, <i>I</i><sup>2</sup> = 0.0%, <i>p</i> = 0.543). Meta-analysis showed no significant association between <i>APOE</i> polymorphism and functional outcomes after SAH with random effects models (ε4 carrier vs. non-ε4 carrier: HR, 1.51; 95% CI: 0.80–2.84, <i>I</i><sup>2</sup> = 57.1%, <i>p</i> = 0.022). <b><i>Conclusions:</i></b> In conclusion, the present study demonstrated <i>APOE</i> ε4 carriers show worse functional outcomes after ICH, but not after IS or SAH. More large-scale studies were critical to explore the association between <i>APOE</i> polymorphism and clinical outcome after IS, ICH, and SAH.

Prognostic factors of clinical outcome after neuronavigation-assisted hematoma drainage in patients with spontaneous intracerebral hemorrhage

2014 ◽  
Vol 123 ◽  
pp. 83-89 ◽  
Author(s):  
Woo-Keun Kwon ◽  
Dong-Hyuk Park ◽  
Kyung-Jae Park ◽  
Shin-Hyuk Kang ◽  
Jeong-Hyun Lee ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage

The impact of hyperacute blood pressure lowering on the early clinical outcome following intracerebral hemorrhage

2008 ◽  
Vol 26 (10) ◽  
pp. 2016-2021 ◽  
Author(s):  
Ryo Itabashi ◽  
Kazunori Toyoda ◽  
Masahiro Yasaka ◽  
Takahiro Kuwashiro ◽  
Hideaki Nakagaki ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
Blood Pressure Lowering ◽  
Pressure Lowering ◽  
The Impact

scholarly journals CORRELATION C-REACTIVE PROTEIN LEVELS WITH CLINICAL OUTCOME INTRACEREBRAL HEMORRHAGE STROKE PATIENTS

2015 ◽  
Vol 1 (1) ◽  
pp. 23-27
Author(s):  
Catur Ari Setianto ◽  
Hari Purnomo ◽  
Eko Arisetijono ◽  
Widodo Mardi Santoso
Keyword(s):  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
C Reactive Protein ◽  
Stroke Patients ◽  
Protein Levels ◽  
Reactive Protein

The association between plasma HMGB1 and sRAGE and clinical outcome in intracerebral hemorrhage

2020 ◽  
Vol 345 ◽  
pp. 577266 ◽  
Author(s):  
Chunyan Lei ◽  
Jia Geng ◽  
Lianmei Zhong
Keyword(s):  
Clinical Outcome ◽  
Intracerebral Hemorrhage

Renal Impairment Is Associated with Intracerebral Hemorrhage after Mechanical Thrombectomy in Vertebrobasilar Stroke

2019 ◽  
Vol 47 (1-2) ◽  
pp. 48-56 ◽  
Author(s):  
Mona Laible ◽  
Ekkehart Jenetzky ◽  
Markus A. Möhlenbruch ◽  
Ulf Neuberger ◽  
Martin Bendszus ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Intracerebral Hemorrhage ◽  
Mechanical Thrombectomy ◽  
Posterior Circulation ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Poor Clinical Outcome ◽  
Treatment Results ◽  
Risk Of Mortality ◽  
Vertebrobasilar Stroke

Background and Purpose: Renal dysfunction (RD) is overall associated with unfavorable functional outcome and higher risk of mortality after acute ischemic stroke. Associations between RD and outcome in patients with acute vertebrobasilar stroke treated with thrombectomy have not been evaluated so far. Materials and Methods: Consecutive patients with vertebrobasilar stroke treated with mechanical thrombectomy between October 2010 and July 2017 at our center were analyzed. RD was defined as glomerular filtration rate (GFR) < 60 mL/min/1.73 m2 at admission. Endpoints were (I) poor clinical outcome (modified Rankin Scale > 2) at 3 months, (II) 3-month mortality, and (III) intracerebral hemorrhage (ICH) after treatment. Results: Overall, 106 patients were included. Median age was 73.0 years (interquartile range 62.0–80.0), and RD was present in 20.8%. Multivariate analysis revealed that RD was associated with a higher risk for any ICH (OR 3.54; 95% CI 1.09–11.49; p = 0.035). Stroke severity at onset predicted poor clinical outcome (OR 1.08; 95% CI 1.03–1.14; p = 0.003). Neither low GFR nor any ICH, but stroke severity (OR 1.08; 95% CI 1.03–1.14; p = 0.002) and poor recanalization results (OR 11.38; 95% CI 2.01–64.41; p = 0.006) were associated with a higher risk for mortality. Conclusions: Patients with RD and acute vertebrobasilar stroke should be thoroughly monitored to prevent ICH after thrombectomy. Our results support performing mechanical thrombectomy in acute stroke patients with large vessel occlusions of the posterior circulation, irrespective of their renal function.

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