Scientific Explanation and Trade-Offs Between Explanatory Virtues

Author(s):  
Alirio Rosales ◽  
Adam Morton
2021 ◽  
Vol 12 (2) ◽  
pp. 672-690
Author(s):  
Natália Cibele De Sousa Santos ◽  
Daniel Ribeiro Gomes ◽  
Jarbas Ancelmo Da Silva Júnior ◽  
Stella Jacyszyn Bachega ◽  
Dalton Matsuo Tavares

Given an increase in consumer demand for product quality, companies need to continually improve their means of production. The use of computational resources assists companies to choose an ordering system that best suits their reality. In this sense, the present study aims to analyze and compare the performance of the Paired-cell Overlapping Loops of Cards with Authorization (POLCA) system, according to pre-established parameters in a real automobile company case, which has a flow-shop production environment. In order to do this, the research has a hypothetical-deductive scientific explanation. Also, the quantitative approach, and the experimental research procedure were employed due to the use of simulation and optimization. The computer simulation was performed using ProModel®. The initial model was optimized, and the results of the two elaborated scenarios were compared. It was verified that the optimized scenario showed improvement in the average total output of the system. The simulation of the optimized model presented an increase in production of approximately 95.29% when compared to the initial scenario. Nevertheless, trade-offs were verified. It is noticeable in the scenario analyzed that to increase the production of axles, the use of intermediate stocks must be increased. Finally, the present research contributes to the academic community since it proposed the study of an ordering system that has a limited number of studies, mainly in Brazil. It also contributes to the business community by encouraging the use of simulation in companies so that a better performance analysis of ordering systems can be performed prior to actual deployment.


Author(s):  
Anjan Chakravartty

To a great extent, the recent renaissance in the metaphysics of science has been spurred by an interest in the nature of causal powers (dispositions, capacities, tendencies, etc.). In particular, a number of authors have made realism about powers a cornerstone of their interpretations of scientific knowledge (for example, in developing accounts of scientific realism, inter alia). Against the backdrop of an admiration for the explanatory power of powers in this domain, this paper strikes a cautionary note. Is the existence of irreducible powers a commitment that is entailed by taking scientific practice seriously? I consider two approaches to this question: the first concerning the putative requirement of dispositional properties in the context of scientific explanation; the second concerning the putative requirement of these properties in the context of scientific abstraction. Neither, I contend, entails an ontological commitment to powers. This negative, interim conclusion suggests that inferences to the existence of causal powers in scientific contexts are ultimately independent of the science adduced; rather; they are a function of substantive philosophical commitments regarding time-honored disputes between realists and empiricists more generally, about issues such as how trade-offs between ontological commitment and explanatory capacity are properly made. In the philosophical domain, however, the realist has an advantage. For realism about powers better accords with an arguably scientistic consideration of the identities of scientific properties. Thus, interim conclusion notwithstanding, it would seem that powers can do something important for the philosopher of science after all.


2015 ◽  
Vol 58 ◽  
pp. 83-100 ◽  
Author(s):  
Selena Gimenez-Ibanez ◽  
Marta Boter ◽  
Roberto Solano

Jasmonates (JAs) are essential signalling molecules that co-ordinate the plant response to biotic and abiotic challenges, as well as co-ordinating several developmental processes. Huge progress has been made over the last decade in understanding the components and mechanisms that govern JA perception and signalling. The bioactive form of the hormone, (+)-7-iso-jasmonyl-l-isoleucine (JA-Ile), is perceived by the COI1–JAZ co-receptor complex. JASMONATE ZIM DOMAIN (JAZ) proteins also act as direct repressors of transcriptional activators such as MYC2. In the emerging picture of JA-Ile perception and signalling, COI1 operates as an E3 ubiquitin ligase that upon binding of JA-Ile targets JAZ repressors for degradation by the 26S proteasome, thereby derepressing transcription factors such as MYC2, which in turn activate JA-Ile-dependent transcriptional reprogramming. It is noteworthy that MYCs and different spliced variants of the JAZ proteins are involved in a negative regulatory feedback loop, which suggests a model that rapidly turns the transcriptional JA-Ile responses on and off and thereby avoids a detrimental overactivation of the pathway. This chapter highlights the most recent advances in our understanding of JA-Ile signalling, focusing on the latest repertoire of new targets of JAZ proteins to control different sets of JA-Ile-mediated responses, novel mechanisms of negative regulation of JA-Ile signalling, and hormonal cross-talk at the molecular level that ultimately determines plant adaptability and survival.


2016 ◽  
Vol 32 (3) ◽  
pp. 204-214 ◽  
Author(s):  
Emilie Lacot ◽  
Mohammad H. Afzali ◽  
Stéphane Vautier

Abstract. Test validation based on usual statistical analyses is paradoxical, as, from a falsificationist perspective, they do not test that test data are ordinal measurements, and, from the ethical perspective, they do not justify the use of test scores. This paper (i) proposes some basic definitions, where measurement is a special case of scientific explanation; starting from the examples of memory accuracy and suicidality as scored by two widely used clinical tests/questionnaires. Moreover, it shows (ii) how to elicit the logic of the observable test events underlying the test scores, and (iii) how the measurability of the target theoretical quantities – memory accuracy and suicidality – can and should be tested at the respondent scale as opposed to the scale of aggregates of respondents. (iv) Criterion-related validity is revisited to stress that invoking the explanative power of test data should draw attention on counterexamples instead of statistical summarization. (v) Finally, it is argued that the justification of the use of test scores in specific settings should be part of the test validation task, because, as tests specialists, psychologists are responsible for proposing their tests for social uses.


2012 ◽  
Vol 11 (3) ◽  
pp. 118-126 ◽  
Author(s):  
Olive Emil Wetter ◽  
Jürgen Wegge ◽  
Klaus Jonas ◽  
Klaus-Helmut Schmidt

In most work contexts, several performance goals coexist, and conflicts between them and trade-offs can occur. Our paper is the first to contrast a dual goal for speed and accuracy with a single goal for speed on the same task. The Sternberg paradigm (Experiment 1, n = 57) and the d2 test (Experiment 2, n = 19) were used as performance tasks. Speed measures and errors revealed in both experiments that dual as well as single goals increase performance by enhancing memory scanning. However, the single speed goal triggered a speed-accuracy trade-off, favoring speed over accuracy, whereas this was not the case with the dual goal. In difficult trials, dual goals slowed down scanning processes again so that errors could be prevented. This new finding is particularly relevant for security domains, where both aspects have to be managed simultaneously.


2007 ◽  
Vol 62 (9) ◽  
pp. 1073-1074 ◽  
Author(s):  
Kennon M. Sheldon ◽  
Melanie S. Sheldon ◽  
Charles P. Nichols

2007 ◽  
Author(s):  
Poonam Arora ◽  
David H. Krantz ◽  
David Hardisty ◽  
Nicole Peterson ◽  
Kavita Reddy
Keyword(s):  

Nature ◽  
2020 ◽  
Vol 588 (7837) ◽  
pp. 225-226
Author(s):  
Wei Peng
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document