Osteoprotegerin deficiency causes morphological and quantitative damage in epithelial rests of Malassez

2018 ◽  
Vol 49 (3) ◽  
pp. 329-338 ◽  
Author(s):  
Yunfei Wang ◽  
Mengmeng Liu ◽  
Shijian Deng ◽  
Xin Sui ◽  
Linlin Fan ◽  
...  
2018 ◽  
Vol 23 (2) ◽  
pp. 30-36
Author(s):  
Alberto Consolaro ◽  
Mauricio de Almeida Cardoso

ABSTRACT The teeth become very close to each other when they are crowded, but their structures remain individualized and, in this situation, the role of the epithelial rests of Malassez is fundamental to release the EGF. The concept of tensegrity is fundamental to understand the responses of tissues submitted to forces in body movements, including teeth and their stability in this process. The factors of tooth position stability in the arch - or dental tensegrity - should be considered when one plans and perform an orthodontic treatment. The direct causes of the mandibular anterior crowding are decisive to decide about the correct retainer indication: Should they be applied and indicated throughout life? Should they really be permanently used for lifetime? These aspects of the mandibular anterior crowding and their implication at the orthodontic practice will be discussed here to induct reflections and insights for new researches, as well as advances in knowledge and technology on this subject.


Oral Oncology ◽  
2005 ◽  
Vol 41 (1) ◽  
pp. 99-100 ◽  
Author(s):  
J. Bascones ◽  
F. Llanes

2017 ◽  
Vol 22 (3) ◽  
pp. 119-125
Author(s):  
Bianca Silva e Silva ◽  
Nathalia Carolina Fernandes Fagundes ◽  
Bárbara Catarina Lima Nogueira ◽  
José Valladares Neto ◽  
David Normando ◽  
...  

ABSTRACT Introduction: The epithelial rests of Malassez (ERM) represent a group of cells in the periodontal ligament classically consisting of latent or quiescent structures associated with pathological processes. However, recent evidence shows that these structures cannot be considered only as cellular debris. The ERM is a major tissue structure, with functions in maintaining the homeostasis of periodontal tissue, including the maintenance of orthodontic movement. Objective: The present literature review aims at presenting the potential functions of ERM, with emphasis on orthodontic movement and the functional structure of the periodontium. Conclusion: ERM cells have a functional activity in modulation of orthodontic movement, trough their potential for differentiation, maintenance functions and the capacity of repairing periodontium.


2010 ◽  
Vol 342 (3) ◽  
pp. 391-400 ◽  
Author(s):  
Yüksel Korkmaz ◽  
Franz-Josef Klinz ◽  
Thomas Beikler ◽  
Thorsten Blauhut ◽  
Kurt Schneider ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Teruyoshi Koshihara ◽  
Kenichi Matsuzaka ◽  
Toru Sato ◽  
Takashi Inoue

Background and Objective. The aim of this study was to investigate the behavior of cells from epithelial rest of Malassez (ERM) against stretching force.Material and Methods. ERM-cultured cells were stretched for 1 hour, at the cycle of 18% elongation for 1 second followed by 1-second relaxation. The cells without addition of stretching force were used as controls. The cells were observed by immunohistochmical staining using actin 0, 12, 24, 36, 48, and 72 hours. Furthermore, expressions of HSP70-, VEGF-, and OPN-mRNAs of cells were also evaluated using quantitative RT-PCR.Results. Actin filaments were randomly orientated in the cytoplasm in the control group, whereas in the stretching group, actin filaments were orientated comparatively parallel to the stretching direction. Expression of HSP70-mRNA in the stretching group was significantly higher than that of control group at 12, 24, 36 hours (P<.05). Expression of VEGF-mRNA in the stretching group was significantly higher than that of control group at 24, 36, 48, and 72 hours (P<.05). Expression of OPN-mRNA in the stretching group was significantly higher than that of control group at 12 and 24 hours (P<.05).Conclusion. ERM cells response against the stretching force by expressing HSP70, VEGF, and OPN.


2012 ◽  
Vol 120 (6) ◽  
pp. 484-494 ◽  
Author(s):  
Kyoko Oka ◽  
Masakazu Morokuma ◽  
Kyoko Imanaka-Yoshida ◽  
Yoshihiko Sawa ◽  
Keitaro Isokawa ◽  
...  

2020 ◽  
Vol 25 (6) ◽  
pp. 19-25
Author(s):  
Alberto Consolaro ◽  
Omar Hadaya ◽  
Mauricio de Almeida Cardoso

ABSTRACT Introduction: Teeth frequently fail to erupt and situations arise that prevent the canines from reaching the occlusal plane. Objective: Discourse about the three situations in which the canine does not reach the occlusal plane, and remains unerupted; and at the same time, point how to make a safe diagnosis of alveolodental ankylosis - one of the three causes -, based on tomography. Conclusions: Ankylosis occurs in impacted teeth by atrophy of the periodontal ligament, including the epithelial rests of Malassez. The tomographic signs of alveolodental ankylosis in unerupted canines are the interruption of hypodense periodontal space, discontinuity of the lamina dura and its continuity with the root surface, which gradually loses its regular shape.


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