Ginger rhizome enhances the anti-inflammatory and anti-nociceptive effects of paracetamol in an experimental mouse model of fibromyalgia

2018 ◽  
Vol 26 (4) ◽  
pp. 1093-1101 ◽  
Author(s):  
Sergio Montserrat-de la Paz ◽  
Maria Dolores Garcia-Gimenez ◽  
Ana Maria Quilez ◽  
Rocio De la Puerta ◽  
Angeles Fernandez-Arche
Keyword(s):  
Mouse Model ◽  
Experimental Mouse Model ◽  
Ginger Rhizome ◽  
Experimental Mouse ◽  
Anti Inflammatory

scholarly journals Anti-inflammatory effects of ozonated water in an experimental mouse model

2014 ◽  
Vol 2 (5) ◽  
pp. 671-674 ◽  
Author(s):  
KAZUO AZUMA ◽  
TAKURO MORI ◽  
KINYA KAWAMOTO ◽  
KOHEI KURODA ◽  
TAKESHI TSUKA ◽  
...  
Keyword(s):  
Mouse Model ◽  
Experimental Mouse Model ◽  
Experimental Mouse ◽  
Anti Inflammatory ◽  
Ozonated Water

scholarly journals Intestinal anti-inflammatory activity of Ulva ohnoi oil in DSS-induced experimental mouse model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
JeongEun Kang ◽  
JiSun Park ◽  
Jung-Kil Seo ◽  
WonHyung Choi ◽  
SooCheol Choi ◽  
...  
Keyword(s):  
Mouse Model ◽  
Large Scale ◽  
Physiological Activity ◽  
Animal Experiments ◽  
Green Tide ◽  
Control Group ◽  
Experimental Mouse Model ◽  
Experimental Mouse ◽  
Ulva Ohnoi ◽  
Anti Inflammatory

AbstractThis study was conducted to examine the physiological activity of Ulva ohnoi, some of which may be used for food or natural products but could disturbing coastal ecosystems due to large scale green-tide, to check values of U. ohnoi oil through experimental results. U. ohnoi oil was extracted from bulk of Ulva biomass to confirm its antioxidant and antibacterial activity, and the efficacy of U. ohnoi oil in the state of inflammation was confirmed through animal experiments. To confirm the anti-inflammatory effect, a mouse model induced with DSS was used. As a result of measuring NO using plasma after induction of inflammation, the amount of NO produced in the U. ohnoi oil group was decreased compared to the control group. Expression of inflammatory cytokines TNF-α, IL-6, and IL-1β was decreased compared to the control group. As a result of observing H&E staining, lower crypt loss and inflammatory cell infiltration were found in the U. ohnoi oil group compared to the control group. Consequently, U. ohnoi oil appears to have great anti-inflammatory properties.

scholarly journals Establishment of an Experimental Mouse Model of Trauma-Hemorrhagic Shock

2012 ◽  
Vol 61 (4) ◽  
pp. 417-425 ◽  
Author(s):  
Yin Tang ◽  
Xue-Feng Xia ◽  
Yun Zhang ◽  
Bing-Feng Huang ◽  
Tao Ma ◽  
...  
Keyword(s):  
Mouse Model ◽  
Hemorrhagic Shock ◽  
Experimental Mouse Model ◽  
Experimental Mouse

scholarly journals Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus

2004 ◽  
Vol 4 (1) ◽  
Author(s):  
Fatih M Uckun ◽  
Alexander S Petkevich ◽  
Alexei O Vassilev ◽  
Heather E Tibbles ◽  
Leonid Titov
Keyword(s):  
Mouse Model ◽  
Hemorrhagic Fever ◽  
Lassa Virus ◽  
Viral Hemorrhagic Fever ◽  
Experimental Mouse Model ◽  
Experimental Mouse

Localized Administration of Doxycycline Suppresses Aortic Dilatation in an Experimental Mouse Model of Abdominal Aortic Aneurysm

2006 ◽  
Vol 20 (2) ◽  
pp. 228-236 ◽  
Author(s):  
Michel A. Bartoli ◽  
Federico E. Parodi ◽  
Jack Chu ◽  
Monica B. Pagano ◽  
Dongli Mao ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Mouse Model ◽  
Aortic Dilatation ◽  
Abdominal Aortic ◽  
Experimental Mouse Model ◽  
Experimental Mouse

scholarly journals A Monoiodotyrosine Challenge Test in a Parkinson’s Disease Model

Acta Naturae ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 106-109
Author(s):  
Alexander R. Kim ◽  
Ekaterina N. Pavlova ◽  
Viktor E. Blokhin ◽  
Vsevolod V. Bogdanov ◽  
Michael V. Ugrumov
Keyword(s):  
Mouse Model ◽  
Disease Model ◽  
Challenge Test ◽  
Motor Impairment ◽  
Striatal Dopamine ◽  
Diagnostic Challenge ◽  
Parkinsons Disease ◽  
Experimental Mouse Model ◽  
Experimental Mouse ◽  
Preclinical Diagnosis

Early (preclinical) diagnosis of Parkinsons disease (PD) is a major challenge in modern neuroscience. The objective of this study was to experimentally evaluate a diagnostic challenge test with monoiodotyrosine (MIT), an endogenous inhibitor of tyrosine hydroxylase. Striatal dopamine was shown to decrease by 34% 2 h after subcutaneous injection of 100 mg/kg MIT to intact mice, with the effect not being amplified by a further increase in the MIT dose. The selected MIT dose caused motor impairment in a neurotoxic mouse model of preclinical PD, but not in the controls. This was because MIT reduced striatal dopamine to the threshold of motor symptoms manifestation only in PD mice. Therefore, using the experimental mouse model of preclinical PD, we have shown that a MIT challenge test may be used to detect latent nigrostriatal dysfunction.

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