scholarly journals Intestinal anti-inflammatory activity of Ulva ohnoi oil in DSS-induced experimental mouse model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
JeongEun Kang ◽  
JiSun Park ◽  
Jung-Kil Seo ◽  
WonHyung Choi ◽  
SooCheol Choi ◽  
...  
Keyword(s):  
Mouse Model ◽  
Large Scale ◽  
Physiological Activity ◽  
Animal Experiments ◽  
Green Tide ◽  
Control Group ◽  
Experimental Mouse Model ◽  
Experimental Mouse ◽  
Ulva Ohnoi ◽  
Anti Inflammatory

AbstractThis study was conducted to examine the physiological activity of Ulva ohnoi, some of which may be used for food or natural products but could disturbing coastal ecosystems due to large scale green-tide, to check values of U. ohnoi oil through experimental results. U. ohnoi oil was extracted from bulk of Ulva biomass to confirm its antioxidant and antibacterial activity, and the efficacy of U. ohnoi oil in the state of inflammation was confirmed through animal experiments. To confirm the anti-inflammatory effect, a mouse model induced with DSS was used. As a result of measuring NO using plasma after induction of inflammation, the amount of NO produced in the U. ohnoi oil group was decreased compared to the control group. Expression of inflammatory cytokines TNF-α, IL-6, and IL-1β was decreased compared to the control group. As a result of observing H&E staining, lower crypt loss and inflammatory cell infiltration were found in the U. ohnoi oil group compared to the control group. Consequently, U. ohnoi oil appears to have great anti-inflammatory properties.

scholarly journals Anti-inflammatory effects of ozonated water in an experimental mouse model

2014 ◽  
Vol 2 (5) ◽  
pp. 671-674 ◽  
Author(s):  
KAZUO AZUMA ◽  
TAKURO MORI ◽  
KINYA KAWAMOTO ◽  
KOHEI KURODA ◽  
TAKESHI TSUKA ◽  
...  
Keyword(s):  
Mouse Model ◽  
Experimental Mouse Model ◽  
Experimental Mouse ◽  
Anti Inflammatory ◽  
Ozonated Water

scholarly journals Constipation-relieving effect of L-arabinose

2020 ◽  
Vol 19 (1) ◽  
pp. 95-99
Author(s):  
Hao Wang ◽  
Wenxian Zhang ◽  
Bin Jiang
Keyword(s):  
Mouse Model ◽  
Control Group ◽  
High Dose ◽  
Fecal Pellets ◽  
Experimental Mouse Model ◽  
Model Control ◽  
Model Control Group ◽  
Experimental Mouse ◽  
Dose Levels ◽  
Medium Dose

Purpose: To investigate the mitigating effect of L-arabinose on constipation in a mouse model of experimental constipation.Methods: Kunming mice were used as experimental animals to establish a constipation model. Intestinal propulsion, first defecation time, number of defecation pellets, and the weight of defecation pellets in 5 h were measured. L-Arabinose was given at 3 dose levels, viz, low dose (0.5 g/kg/day),medium dose (0.75 g/kg/day), and high dose (2.5 g/kg/day), and their effects on constipation were compared with that of the model control group.Results: Compared with the model control group, there were significant differences in ink propulsion (F= 22.67, p < 0.05); time taken for first black stool to appear (F = 19.51, p < 0.05), number of fecal pellets (F = 12.22, p < 0.05), and fecal weight (F = 5, p < 0.05) in the L-arabinose groups.Conclusion: L-Arabinose relieves constipation symptoms in an experimental mouse model of constipation. Therefore, L-arabinose may be useful in the management of patients with constipation, but further studies in humans are required to ascertain this. Keywords: L-Arabinose, Fecal pellets/grains, Constipation, Stool, Intestinal propulsion

scholarly journals Pulmonary changes during acute experimental murine manson schistosomiasis

2009 ◽  
Vol 42 (1) ◽  
pp. 5-8 ◽  
Author(s):  
Samaly dos Santos Souza ◽  
Joaquim Pereira de Souza Neto ◽  
Zilton A. Andrade
Keyword(s):  
Mouse Model ◽  
Acute Phase ◽  
Inflammatory Mediators ◽  
The Other ◽  
Control Group ◽  
Inflammatory Lesions ◽  
Experimental Mouse Model ◽  
Infected Control Group ◽  
Experimental Mouse ◽  
Pulmonary Changes

Dry cough, dyspnea and manifestations of bronchial asthma have recently been observed in patients with acute schistosomiasis. To investigate the type and pathogenesis of these conditions, an experimental mouse model for acute schistosomiasis was used. Forty mice were divided into four groups of ten each: three infected groups and a non-infected control group. The animals were examined 7, 28-35 and 40 days after exposure to cercariae. During the acute phase of the infection (28-35 days), a process of multifocal interstitial pneumonitis involving the peribronchial, peribronchiolar and subpleural tissues was found. This process was not seen during the other phases of the infection. Indirect immunofluorescence failed to demonstrate the presence of schistosomal antigens in the acute-phase lesions. The pneumonitis was attributed to products (inflammatory mediators) from acute-phase periovular necrotic-inflammatory lesions in the liver that were transported to the lungs by the bloodstream.

Ginger rhizome enhances the anti-inflammatory and anti-nociceptive effects of paracetamol in an experimental mouse model of fibromyalgia

2018 ◽  
Vol 26 (4) ◽  
pp. 1093-1101 ◽  
Author(s):  
Sergio Montserrat-de la Paz ◽  
Maria Dolores Garcia-Gimenez ◽  
Ana Maria Quilez ◽  
Rocio De la Puerta ◽  
Angeles Fernandez-Arche
Keyword(s):  
Mouse Model ◽  
Experimental Mouse Model ◽  
Ginger Rhizome ◽  
Experimental Mouse ◽  
Anti Inflammatory

scholarly journals Establishment of an Experimental Mouse Model of Trauma-Hemorrhagic Shock

2012 ◽  
Vol 61 (4) ◽  
pp. 417-425 ◽  
Author(s):  
Yin Tang ◽  
Xue-Feng Xia ◽  
Yun Zhang ◽  
Bing-Feng Huang ◽  
Tao Ma ◽  
...  
Keyword(s):  
Mouse Model ◽  
Hemorrhagic Shock ◽  
Experimental Mouse Model ◽  
Experimental Mouse

scholarly journals Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus

2004 ◽  
Vol 4 (1) ◽  
Author(s):  
Fatih M Uckun ◽  
Alexander S Petkevich ◽  
Alexei O Vassilev ◽  
Heather E Tibbles ◽  
Leonid Titov
Keyword(s):  
Mouse Model ◽  
Hemorrhagic Fever ◽  
Lassa Virus ◽  
Viral Hemorrhagic Fever ◽  
Experimental Mouse Model ◽  
Experimental Mouse
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