Calcium carbonate prevents Botryococcus braunii growth inhibition caused by medium acidification

2021 ◽  
Author(s):  
Ryoji Miura ◽  
Kenichi Furuhashi ◽  
Fumio Hasegawa ◽  
Yutaka Kaizu ◽  
Kenji Imou
Keyword(s):  
Calcium Carbonate ◽  
Growth Inhibition ◽  
Botryococcus Braunii ◽  
Medium Acidification

scholarly journals Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo

Nanoscale ◽  
2016 ◽  
Vol 8 (25) ◽  
pp. 12639-12647 ◽  
Author(s):  
Avik Som ◽  
Ramesh Raliya ◽  
Limei Tian ◽  
Walter Akers ◽  
Joseph E. Ippolito ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Tumor Growth ◽  
Growth Inhibition ◽  
Extracellular Ph ◽  
Tumor Growth Inhibition ◽  
Inhibit Tumor Growth ◽  
Local Ph

Intravenously administered CaCO3 nanoparticles can induce tumor growth inhibition via local increases in tumor extracellular pH in vivo.

A High-Throughput Crystallization Device to Study Biomineralization in Vitro

2005 ◽  
Vol 873 ◽  
Author(s):  
Alexander Becker ◽  
Matthias Epple
Keyword(s):  
Crystal Growth ◽  
Calcium Carbonate ◽  
Growth Inhibition ◽  
Aspartic Acid ◽  
High Throughput ◽  
Double Diffusion ◽  
Constant Composition ◽  
Crystal Growth Inhibition

AbstractA new crystallization device, based on a constant-composition double-diffusion setup, was constructed to study biomineralization in vitro. The device was tested with poly(aspartic acid) as a model additive in the precipitation of calcium carbonate, showing a complete crystal growth inhibition.

Fabrication of Alginate/Calcium Carbonate Hybrid Microparticles for Synergistic Drug Delivery

Chemotherapy ◽  
2015 ◽  
Vol 61 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Yan Peng ◽  
Hua-Yan Sun ◽  
Zong-Chun Wang ◽  
Xiao-Ding Xu ◽  
Jin-Chun Song ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Carbonate ◽  
Cell Growth ◽  
Growth Inhibition ◽  
Colloidal Stability ◽  
In Vitro Study ◽  
Cell Growth Inhibition ◽  
Reversal Agent ◽  
Delivery Platform

A hybrid drug delivery system coloaded with different drugs for synergistic drug delivery was developed. Alginate/calcium carbonate (CaCO3) hybrid microparticles (MPs) were fabricated via a facile coprecipitation method under mild conditions without using any organic solvent and surfactant. Due to the incorporation of negatively charged alginate chains onto the surface, the obtained hybrid MPs with spherical morphology showed good colloidal stability in an aqueous solution. An antitumor drug (doxorubicin, DOX) and a drug resistance reversal agent (verapamil, VP) were coloaded in the hybrid MPs simultaneously to obtain dual-drug-loaded MPs (DOX/VP/MP). Due to the presence of inorganic CaCO3 (∼54 wt%), the drugs could be loaded in the hybrid MPs with high encapsulation efficiency and the drug release could be effectively sustained. The cell growth inhibition of the drug-loaded MPs was evaluated in HeLa cells. An in vitro study showed DOX/VP/MP exhibited higher cell growth inhibition as compared with DOX monodrug-loaded MPs (DOX/MP). These results suggest the hybrid MPs can potentially be used as a synergistic drug delivery platform for cancer chemotherapy.

A TEM study of the microstructure of avian eggshells

1992 ◽  
Vol 50 (2) ◽  
pp. 1102-1103
Author(s):  
S. Q. Xiao ◽  
S. Baden ◽  
A. H. Heuer
Keyword(s):  
Electron Microscope ◽  
Calcium Carbonate ◽  
Nucleation And Growth ◽  
Growth Mechanisms ◽  
Shell Surface ◽  
Thin Sections ◽  
Polycrystalline Metals ◽  
Transmission Electron ◽  
Nucleation And Growth Mechanisms

The avian eggshell is one of the most rapidly mineralizing biological systems known. In situ, 5g of calcium carbonate are crystallized in less than 20 hrs to fabricate the shell. Although there have been much work about the formation of eggshells, controversy about the nucleation and growth mechanisms of the calcite crystals, and their texture in the eggshell, still remain unclear. In this report the microstructure and microchemistry of avian eggshells have been analyzed using transmission electron microscope (TEM) and energy dispersive spectroscopy (EDS).Fresh white and dry brown eggshells were broken and fixed in Karnosky's fixative (kaltitanden) for 2 hrs, then rinsed in distilled H2O. Small speckles of the eggshells were embedded in Spurr medium and thin sections were made ultramicrotome.The crystalline part of eggshells are composed of many small plate-like calcite grains, whose plate normals are approximately parallel to the shell surface. The sizes of the grains are about 0.3×0.3×1 μm3 (Fig.l). These grains are not as closely packed as man-made polycrystalline metals and ceramics, and small gaps between adjacent grains are visible indicating the absence of conventional grain boundaries.

Light-induced increase in the contents of ferulic and diferulic acids in cell walls of Avena coleoptiles: its relationship to growth inhibition by light

1994 ◽  
Vol 92 (2) ◽  
pp. 350-355 ◽  
Author(s):  
Kensuke Miyamoto ◽  
Junichi Ueda ◽  
Satomi Takeda ◽  
Kazuko Ida ◽  
Takayuki Hoson ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Cell Walls

Scaling risk assessment in a closed circuit recycled board mill by speciation methods

TAPPI Journal ◽  
2012 ◽  
Vol 11 (5) ◽  
pp. 53-61 ◽  
Author(s):  
PATRICK HUBER ◽  
SYLVIE NIVELON ◽  
PATRICE NORTIER
Keyword(s):  
Calcium Carbonate ◽  
Volatile Fatty Acids ◽  
Inorganic Carbon ◽  
Stability Index ◽  
Closed Circuit ◽  
Critical Problem ◽  
Local Scaling ◽  
Water Analyses ◽  
Closed Water ◽  
Speciation Calculation

Calcium carbonate scaling often is a critical problem for recycled board mills that have closed water circuits. The objective of this study was to determine local scaling risks throughout the production process. To predict scaling potential, we calculated several saturation indexes, based on speciation determined from detailed water analyses. Calculated scaling trends are in accordance with observed dissolution and precipitation of calcium carbonate in the process, when considering local aeration phenomena. The importance of volatile fatty acids (resulting from anaerobic bacterial activity) in calco-carbonic equilibriums is discussed, and taken into account in the speciation calculation. We also demonstrate the need to measure inorganic carbon instead of alkalinity in such conditions. This makes typical scaling indexes, such as the Ryznar Stability Index, irrelevant to predict scaling risk in closed circuit conditions; thus, it is necessary to use general speciation methods, as described in this paper.

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