A novel chromosomal translocation and heteromorphism in a female with recurrent pregnancy loss—a case study

Ayurveda emphasized on four main essential factors for fertility i.e. Ritu(menstruation),Kshetra(functioning reproductive organs),Ambu(Digestive juices) and Bija(Healthy sperm and ovum) .Abnormality in any one of this factors causes infertility.Infertility is a failure to conceive within one or more years of regular unprotected coitus.Primary infertility denotes who has never conceived and secondary indicates previous pregnancy but failure to conceive subsequently. Secondary Infertilily with recurrent pregnancy loss because of Viral infections like TORCH is a worrisome issue for the reproductive couple.Majority of early missed abortions and spontaneous abortion are seen in current population of country.Toxoplasmosis,cytomegaly virus,rubella and herpes simplex viruses are responsible for manifestation of the maternal infections causing early pregnancy loss.According to Ayurveda recurrent pregnancy loss is specified under Putraghni yonivyapad and specific treatment like Uttarbasti is described for the same. As yoniyapada leads to infertility because of vikrit Vata ,ultimately the treatment of Vata i.e. bastichikitsa is seen very beneficial in the treatment of Infertility.

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RESCUE CERVICAL CERCLAGE: PREVENTION OF A PREVIABLE BIRTH

10.36106/gjra/0503915 ◽

2021 ◽

pp. 36-37

Author(s):

D. Sruthi ◽

V. Radhalakshmi

Keyword(s):

Uterine Cervix ◽

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Signs And Symptoms ◽

Salvage Procedure ◽

Second Trimester ◽

Cervical Cerclage ◽

Successful Pregnancy ◽

In Pregnancy

Pregnancy loss at any stage is distressing especially when this happens later in pregnancy, and this further worsens when it recurs in subsequent pregnancies. The reasons for recurrent pregnancy loss and preterm delivery are diverse and multifactorial. One of the main reasons for these complications is cervical insufciency, which means the inability of the uterine cervix to retain a pregnancy in the absence of signs and symptoms of clinical contractions, or labor or both in second trimester. Rescue cervical cerclage also known as Emergency cerclage/ rescue stitch is fundamentally a salvage procedure to prolong pregnancy in women with advanced cervical dilatation or prolapsed membranes in the second +3 trimester. Here, we present a case study of a 25-year-old antenatal woman Gravida 4 Para 0 with advanced cervical changes at 20 weeks who beneted from the rescue cervical cerclage procedure to have a successful pregnancy outcome.

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MANAGEMENT OF RECURRENT PREGNANCY LOSS W.S.R PUTRAGHANI YONIVYAPADA WITH AYURVEDIC REGIMEN: A CASE STUDY

November 2020 - International Ayurvedic Medical Journal ◽

10.46607/iamj4009042021 ◽

2021 ◽

Vol 9 (4) ◽

pp. 916-922

Author(s):

Poonam Kumari ◽

Poonam Choudhary ◽

Sonu Sonu ◽

Hetal H. Dave

Keyword(s):

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Treatment Plan ◽

Postnatal Period ◽

Detailed History ◽

Habitual Abortion ◽

Physical Examinations ◽

Laboratory Investigations ◽

Rule Out

Background: A married Hindu female patient of 37 years of age visited to OPD of National institute of Ayurveda, Jaipur on 19 April 2019 with chief complaint of recurrent pregnancy loss since 7 years. Methodology: Patient was interrogated for detailed history about her chief as well as associated complaints. Following detailed history neces- sary physical examinations and laboratory investigations were carried out to rule out the aetiology. Her TORCH test IgG and IgM antibodies was carried out and she was found to have Rubella IgG, Cytomegalovirus IgG, and HSV IgG antibodies positive. Other investigations including TFT, PRL, USG scan was found to be normal. Based on the complaints diagnosis made was Putraghani Yonivyapada (Recurrent pregnancy loss or Habitual abortion). Treatment plan was laid out accordingly on the basis of complaints and etiological factors. She managed to conceive 6 months after the treatment. She was given proper antenatal care with all necessary examinations and advices. Result: She delivered a healthy male baby on 20th July 2020 without any event during her antenatal, perinatal and postnatal period. Keywords: Putraghani yonivyapada, Recurrent pregnancy loss, Habitual abortion

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The Role of Panchakarma in recurrent pregnancy loss- A case study

National Journal of Research in Ayurved Science ◽

10.52482/ayurlog.v6i5th.197 ◽

2018 ◽

Vol 6 (5th) ◽

Author(s):

Amol Kanodje ◽

Vijay Kumar Nawle

Keyword(s):

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Bed Rest ◽

First Trimester ◽

Second Trimester ◽

Foetal Distress ◽

Spontaneous Pregnancy ◽

Female Baby

Recurrent pregnancy loss is defined as three or more consecutive spontaneous losses of pregnancy. In Ayurvedic samhita â€œGarbhastraviVandhyaâ€ is a term for recurrent habitual abortion in the first trimester and â€œGarbhapataâ€ in second trimester up to 20 weeks from the last menstrual period. Spontaneous pregnancy loss is a surprisingly common occurrence and affects 1% of couples trying to conceive. The best available data suggest that the risk of miscarriage in subsequent pregnancies is 30% after 2 losses, compared with 33% after 3 losses.1 In this case study, interpretation of cause is done on basics of Ayurvedic diagnostic parameters and management is done according to that. Deepan, pachan, panchakarma specially Uttar vasti were planned before conception and after conception complete bed rest along with proper antenatal medicines and advices were given. There was uneventful antenatal period except foetal distress at 39.5 weeks of gestation and the patient was delivered by emergency caesarean section. A female baby with 3.1 kg birth weight was born.

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The importance of MTHFR gene mutation detection in patient with recurrent miscarriages

Genetika ◽

10.2298/gensr1502609d ◽

2015 ◽

Vol 47 (2) ◽

pp. 609-616

Author(s):

Klaudija Daugėlaitė ◽

Danielius Serapinas

Keyword(s):

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Methylenetetrahydrofolate Reductase ◽

Molecular Genetic ◽

Mthfr Gene ◽

Chromosome 1 ◽

Recurrent Miscarriages ◽

Reductase Gene ◽

Methylenetetrahydrofolate Reductase Gene

Homocysteine is an enzyme encoded by MTHFR (methylenetetrahydrofolate reductase) gene located on chromosome 1. Mutations in MTHFR gene may result in the afflicted metabolism of homocysteine and thus might increase the risk of recurrent miscarriages. In some cases, recurrent pregnancy loss could be prevented by prescribing folic acid and B group vitamin supplements. The demand of MTHFR gene sequencing for variations is commonly overlooked by doctors or genetic counsellors. To highlight this problem we present a case study of recurrent miscarriages in a patient with a homozygous c. 655C>T variation in MTHFR gene. Moreover, we discuss the need of molecular genetic testing for MTHFR gene variations in patients with recurrent miscarriages and the treatment of hyperhomocysteinemia.

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SUCCESSFUL PREGNANCY OUTPUT IN A CASE OF RECURRENT PREGNANCY LOSS BY AYURVEDIC ANC MANAGEMENT- A CASE STUDY

National Journal of Research in Ayurved Science ◽

10.52482/ayurlog.v7i02.301 ◽

2019 ◽

Vol 7 (02) ◽

Author(s):

Dr Ashwini Bhaskar Pawar

Keyword(s):

Pregnancy Loss ◽

Recurrent Pregnancy Loss ◽

Recurrent Miscarriage ◽

First Trimester ◽

Reproductive Age ◽

Antenatal Period ◽

Habitual Abortion ◽

Reproductive Health Issue ◽

Female Baby

Recurrent Pregnancy Loss is an important reproductive health issue, â€œGarbha stravi vandhyaâ€ is a term used in ayurvedic Samhitaâ€™s for recurrent habitual abortion in first trimester. Recurrent pregnancy loss also defined as recurrent miscarriage is historically defined as sequence of three or more consecutive spontaneous abortions before 20weeks. Some however Consider Two or more as standard. It may be Primary or secondary. (Having previous viable birth) This distressing problem is affecting approximately 1% of all women of reproductive age. The risk is increased with each successive abortion reaching over 30% after 3 consecutive cases. In this case Study, Interpretation of case is done on basics of ayurvedic diagnostics parameters and management is designed according to that. So Pachan and antenatal dilatory regimen with ayurvedic medicine where planned. During antenatal period combination of herb Suvarana kalpa, different types of medicated ghruta, Masanumasik Kashaya where used. There was uneventful antenatal period, Cesarean section was done. female baby with 3.3 kg was born. There was no any Neonatal complication. KEY WORDS: Recurrent pregnancy loss, Habitual abortion, Spontaneous abortion

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