scholarly journals SUCCESSFUL PREGNANCY OUTPUT IN A CASE OF RECURRENT PREGNANCY LOSS BY AYURVEDIC ANC MANAGEMENT- A CASE STUDY

2019 ◽  
Vol 7 (02) ◽  
Author(s):  
Dr Ashwini Bhaskar Pawar
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Recurrent Miscarriage ◽  
First Trimester ◽  
Reproductive Age ◽  
Antenatal Period ◽  
Habitual Abortion ◽  
Reproductive Health Issue ◽  
Female Baby

 Recurrent Pregnancy Loss is an important reproductive health issue, “Garbha stravi vandhya” is a term used in ayurvedic Samhita’s for recurrent habitual abortion in first trimester. Recurrent pregnancy loss also defined as recurrent miscarriage is historically defined as sequence of three or more consecutive spontaneous abortions before 20weeks. Some however Consider Two or more as standard. It may be Primary or secondary.  (Having previous viable birth) This distressing problem is affecting approximately 1% of all women of reproductive age. The risk is increased with each successive abortion reaching over 30% after 3 consecutive cases. In this case Study, Interpretation of case is done on basics of ayurvedic diagnostics parameters and management is designed according to that. So Pachan and antenatal dilatory regimen with ayurvedic medicine where planned. During antenatal period combination of herb Suvarana kalpa, different types of medicated ghruta, Masanumasik Kashaya where used. There was uneventful antenatal period, Cesarean section was done. female baby with 3.3 kg was born. There was no any Neonatal complication.   KEY WORDS:  Recurrent pregnancy loss, Habitual abortion, Spontaneous abortion  

The Role of Panchakarma in recurrent pregnancy loss- A case study

2018 ◽  
Vol 6 (5th) ◽  
Author(s):  
Amol Kanodje ◽  
Vijay Kumar Nawle
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Bed Rest ◽  
First Trimester ◽  
Second Trimester ◽  
Foetal Distress ◽  
Spontaneous Pregnancy ◽  
Female Baby

Recurrent pregnancy loss is defined as three or more consecutive spontaneous losses of pregnancy. In Ayurvedic samhita “GarbhastraviVandhya” is a term for recurrent habitual abortion in the first trimester and “Garbhapata” in second trimester up to 20 weeks from the last menstrual period. Spontaneous pregnancy loss is a surprisingly common occurrence and affects 1% of couples trying to conceive. The best available data suggest that the risk of miscarriage in subsequent pregnancies is 30% after 2 losses, compared with 33% after 3 losses.1 In this case study, interpretation of cause is done on basics of Ayurvedic diagnostic parameters and management is done according to that.  Deepan, pachan, panchakarma specially Uttar vasti were planned before conception and after conception complete bed rest along with proper antenatal medicines and advices were given. There was uneventful antenatal period except foetal distress at 39.5 weeks of gestation and the patient was delivered by emergency caesarean section. A female baby with 3.1 kg birth weight was born.

Contemporary Evidence-Based Approach to the Couple Experiencing Recurrent Pregnancy Loss: Standardizing Terminology, Testing, and Treatment

2018 ◽  
Author(s):  
Channing Burks ◽  
Mary D Stephenson ◽  
Danny J Schust
Keyword(s):  
Gestational Age ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Comprehensive Evaluation ◽  
Recurrent Miscarriage ◽  
First Trimester ◽  
Diagnostic Evaluation ◽  
Etiologic Factor ◽  
Evidence Based ◽  
Close Monitoring

The objective of this review is to highlight central issues relating to recurrent pregnancy loss (RPL), including use of updated terminologies, updated criteria for initiating an RPL evaluation, and an evidence-based standard diagnostic evaluation. RPL is a condition characterized by repeated spontaneous demise of pregnancy. It is a multifactorial disorder that affects approximately 5% of couples in the general population who are trying to have a child. RPL should be defined as two or more pregnancy losses at any gestational age; these do not necessarily need to be consecutive. As 50 to 70% of pregnancy losses of less than 10 weeks gestational age are due to random numeric chromosome errors, we recommend chromosome testing of miscarriage tissues with the second and all subsequent miscarriages less than 10 weeks gestational age. If the second pregnancy loss is “unexplained,” meaning that the chromosome content is euploid (46,XX of pregnancy origin, 46,XY, or a balanced structural chromosomal rearrangement), then an RPL diagnostic evaluation is indicated. Despite a comprehensive evaluation, approximately 40% of couples with RPL will not have a specific etiologic factor identified. In these couples, as with all couples experiencing RPL, empirical management with close monitoring and supportive care during the first trimester is associated with encouraging subsequent live birth rates.   This review contains 10 figures, 5 tables and 57 references Key words: factors associated with recurrent pregnancy loss, idiopathic recurrent pregnancy loss, miscarriage chromosome testing, nonvisualized pregnancy loss, pregnancy of unknown location, recurrent miscarriage, recurrent pregnancy loss

scholarly journals MANAGEMENT OF RECURRENT PREGNANCY LOSS W.S.R PUTRAGHANI YONIVYAPADA WITH AYURVEDIC REGIMEN: A CASE STUDY

2021 ◽  
Vol 9 (4) ◽  
pp. 916-922
Author(s):  
Poonam Kumari ◽  
Poonam Choudhary ◽  
Sonu Sonu ◽  
Hetal H. Dave
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Treatment Plan ◽  
Postnatal Period ◽  
Detailed History ◽  
Habitual Abortion ◽  
Physical Examinations ◽  
Laboratory Investigations ◽  
Rule Out

Background: A married Hindu female patient of 37 years of age visited to OPD of National institute of Ayurveda, Jaipur on 19 April 2019 with chief complaint of recurrent pregnancy loss since 7 years. Methodology: Patient was interrogated for detailed history about her chief as well as associated complaints. Following detailed history neces- sary physical examinations and laboratory investigations were carried out to rule out the aetiology. Her TORCH test IgG and IgM antibodies was carried out and she was found to have Rubella IgG, Cytomegalovirus IgG, and HSV IgG antibodies positive. Other investigations including TFT, PRL, USG scan was found to be normal. Based on the complaints diagnosis made was Putraghani Yonivyapada (Recurrent pregnancy loss or Habitual abortion). Treatment plan was laid out accordingly on the basis of complaints and etiological factors. She managed to conceive 6 months after the treatment. She was given proper antenatal care with all necessary examinations and advices. Result: She delivered a healthy male baby on 20th July 2020 without any event during her antenatal, perinatal and postnatal period. Keywords: Putraghani yonivyapada, Recurrent pregnancy loss, Habitual abortion

scholarly journals Runs of homozygosity in spontaneous abortions from families with recurrent pregnancy loss

2019 ◽  
Vol 23 (2) ◽  
pp. 244-249
Author(s):  
N. A. Skryabin ◽  
S. A. Vasilyev ◽  
T. V. Nikitina ◽  
D. I. Zhigalina ◽  
R. R. Savchenko ◽  
...  
Keyword(s):  
High Frequency ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
De Novo ◽  
Recurrent Miscarriage ◽  
Uniparental Disomy ◽  
First Trimester ◽  
Comparative Genomic ◽  
Runs Of Homozygosity ◽  
Recessive Mutations

Recurrent pregnancy loss (RPL) is a severe reproductive pathology with a significant component of unexplained etiology. Extended homozygous regions as a possible etiological factor for RPL were sought in the genomes of embryos. Twenty-two paired first-trimester spontaneously aborted embryos from eleven women with recurrent miscarriage were analyzed. All embryos had normal karyotypes according to metaphase karyotyping and conventional comparative genomic hybridization. SurePrint G3 Human CGH + SNP 4 × 180K microarrays (Agilent Technologies) were used to search for homozygous regions. As a result, 39 runs of homozygosity (ROH) were identified in extraembryonic tissues of 15 abortuses. Verification of recurrent homozygous regions was performed by Sanger sequencing. The presence of occasional heterozygous SNPs was shown in 25 extended ROHs, which may indicate that they did not arise de novo but were inherited from parents. In the course of inheritance in a series of generations, they may accumulate mutations, leading to heterozygosity for several sites in the initially homozygous population-specific regions. Homozygotization of recessive mutations is one of the putative mechanisms of the influence of such inherited ROHs on RPL development. The high frequency of extended ROHs detected in the present study may point to a role of inbreeding in RPL etiology. Homozygous regions may also occur due to uniparental disomy, and abnormalities of genomic imprinting may be another mechanism responsible for the pathological manifestation of ROHs in embryogenesis. Indeed, five predicted imprinted genes were identified within ROHs according to the Geneimprint database: OBSCN, HIST3H2BB, LMX1B, CELF4, and FAM59A. This work reports the first finding of a high frequency of extended ROHs in spontaneously aborted embryos with normal karyotypes from families with RPL.

scholarly journals AYURVED APPROACH TO PUTRAGHNI YONIVYAPADA W.S.R. TO HABITUAL ABORTION DUE TO TORCH INFECTION: CASE STUDY

AYUSHDHARA ◽  
2020 ◽  
pp. 2776-2780
Author(s):  
Divya Pawar ◽  
Sameer Gholap
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Miscarriage ◽  
Treatment Protocol ◽  
Habitual Abortion ◽  
Consecutive Pregnancy ◽  
The Subject ◽  
Torch Infection ◽  
Antenatal Visits ◽  
Repeated Pregnancy Loss

Pregnancy is the start of an incredible journey that leads to great emotional fulfilment to woman. Pregnancy loss is a physically and emotionally demanding for couples. Recurrent Pregnancy Loss (RPL) is also called as Recurrent Miscarriage or Habitual Abortion. It is defined as three consecutive pregnancy losses prior to 20weeks of pregnancy from the last menstrual cycle (LMP). Putraghni is a condition where repeated pregnancy loss occurs because of Artava dosha, Rakta dosha, Ati raktasrava. The article is to understand the Putraghni Yonivyapada w.s.r. to habitual abortion caused due to TORCH Infection and to study the effect of Ayurvedic medicines in the management of Putraghni Yonivyapada w.s.r. to habitual abortion caused due to TORCH Infection. The method is the single arm, open labelled case study of the subject of 27 yrs age having repeated pregnancy loss who has been treated with Shamana Chikitsa throughout pregnancy, Matrabasti and Yonipichu in 8th and 9th months. Pregnancy continued with treatment. Antenatal visits and Ultrasonography observations gave positive outcomes with healthy foetal growth. Patient delivered a full term single live male baby vaginally on 27/10/2019 at 3:20PM with 2.8kg. No birth anomalies were detected. The selected treatment protocol i.e., Shamana Aushadha, Matrabasti and Yonipichu in 8th and 9th month are found very effective in the management of Putraghni Yonivyapada w.s.r. to habitual abortion caused due to TORCH Infection.

Association of of IL-1 receptor antagonist (IL-1RN) and interleukin-1β genes (IL-1β) polymorphisms with recurrent pregnancy loss in Iranian Azeri women

2017 ◽  
Vol 33 (3) ◽  
Author(s):  
Seyyed Ali Rahmani ◽  
Zeynab Paknejad ◽  
Masoumeh Mohammadkhanlou ◽  
Marina Daneshparvar
Keyword(s):  
Receptor Antagonist ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Pcr Amplification ◽  
Rflp Analysis ◽  
First Trimester ◽  
Reproductive Age ◽  
Human Reproduction ◽  
Interleukin 1Β ◽  
Control Group

AbstractObjectiveOne of the most important problems in human reproduction is recurrent pregnancy loss (RPL). RPL is defined as three or more consecutive abortions in the first trimester of pregnancy. The association between the polymorphisms in the immunological factors and RPL was investigated. The aim of our study was to determine the association of interleukin receptor antagonist (IL-IRN) and interleukin-1β (IL-1β) polymorphisms with RPL in Iranian Azeri women.Materials and methodsThe study participants consisted of 100 women with RPL of Iranian Azeri origin. The control group comprised 100 age- and ethnically-matched healthy women of the same reproductive age. Genomic DNA was extracted from the whole blood and genotype determinations were performed using polymerase chain reaction (PCR) amplification followed by restriction fragment length polymorphism (RFLP) analysis.ResultsOur results showed no significant relationship betweenIL-1RNpolymorphism and RPL. The homozygous state in −857 C/T variant was seen to be higher in RPL patients than in control subjects. Also frequency of wild type genotype was lower in RPL patients than in controls. However, this associations was not significant.ConclusionThis study suggested that −511 C/T (rs16944) and −31 C/T (rs1143627) polymorphisms inIL-1βgene may not be involved in RPL in Iranian Azeri women. Also the promoter polymorphism of theIL-1RNgene may not play a role in the susceptibility to RPL.

scholarly journals Pregnancy Complications in Women with PCOS

2019 ◽  
Vol 3 (5) ◽  
Keyword(s):  
Pregnancy Loss ◽  
Polycystic Ovarian Syndrome ◽  
First Trimester ◽  
Reproductive Age ◽  
Multiple Pregnancies ◽  
Proper Understanding ◽  
Life Styles ◽  
Reproductive Age Women ◽  
Increased Risk ◽  
Ovarian Syndrome

The Polycystic ovarian syndrome affects 6-15 % of reproductive age women worldwide. And recently the changing life styles and rising obesity worldwide have contributed to a rise in the incidence of PCOS. Though there are many issues with PCOS post conception. PCOS women are at increased risk of early pregnancy loss which is approx. three fold as compared to the women without PCOS. After successfully crossing the first trimester, they are at risk of developing pre- eclampsia, GDM, preterm birth and birth of small for gestational age infant. Also higher incidence of multiple pregnancies is there and the risks associated with them. All these leading to higher rate of c -section delivery. So, proper understanding of these risks, informing and counseling the patients regarding them facilitate closer maternal and fetal surveillance and help improving the outcome of pregnancy.

O-008 Improving outcomes in women with Mullerian anomalies

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
J Malhotra ◽  
N Malhotra ◽  
N Malhotra
Keyword(s):  
Pregnancy Loss ◽  
Intrauterine Growth Retardation ◽  
Recurrent Pregnancy Loss ◽  
Recurrent Miscarriage ◽  
Obstetric Outcome ◽  
Mullerian Anomalies ◽  
Intrauterine Growth ◽  
Müllerian Anomalies ◽  
Different Types ◽  
Registration Number

Abstract text Mullerian Anomalies are present in approximately 5% to 7% of the general population and the incidence is a little more in infertile and recurrent miscarriage women. Most of the recent studies have reported that the obstetric outcome is compromised in this group with greater risk of infertility, recurrent pregnancy loss, intrauterine growth retardation, preterm birth and many other obstetric complications, which may be individually related to the different types of Mullerian Anomalies. In this presentation, We are going to discuss on how the outcomes are different in the various Mullerian Anomalies depending upon the degree of the defects related to different complications with more profound defects. We will also discuss on how to optimize the pregnancy outcomes with various interventions and what the literature review supports. Trial registration number Study funding Funding source

An evaluation of recurrent pregnancy loss

2017 ◽  
Vol 6 (4) ◽  
pp. 1332 ◽  
Author(s):  
Abha Singh ◽  
Avinashi Kujur ◽  
Kalpana Rathore
Keyword(s):  
Pregnancy Loss ◽  
Genetic Factors ◽  
Recurrent Pregnancy Loss ◽  
First Trimester ◽  
Medical College ◽  
Antenatal Counseling ◽  
History Of ◽  
Immunological Factors ◽  
The Times ◽  
Loving Care

Background: This study was aimed to know the demographic profile and categorizes the causes of RPL.Methods: This observational study was carried out in the department of obstetrics and gynecology, Pt. J.N.M. Medical College Raipur from Nov 2015-Sept 2016. Total 100 women were evaluated with history of RPL.Results: 100 women were recruited in our study. The incidence of primary RPL was more than secondary RPL. 48 % women had first trimester abortions. The identifiable causes accounted for 53% out of which anatomical defects were the commonest .Next were endocrinal factors (20%), and Genetic factors (1%),Immunological factors 7%., Medical causes were 3%. However, 47% were unexplained.Conclusions: Despite innumerable investigations, sometimes or rather most of the times, the etiology remains obscure. It is this group of women who become a challenge to manage. Ultimately, most effective therapy for women with unexplained RPL is antenatal counseling, psychological support and tender loving care.

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