Synthesis and characterization of thiolated carboxymethyl chitosan-graft-cyclodextrin nanoparticles as a drug delivery vehicle for albendazole

2013 ◽  
Vol 24 (8) ◽  
pp. 1939-1949 ◽  
Author(s):  
Ghazaleh Alamdarnejad ◽  
Alireza Sharif ◽  
Shahrouz Taranejoo ◽  
Mohsen Janmaleki ◽  
Mohammad Reza Kalaee ◽  
...  
Author(s):  
Maher Fathalla

The development of synthetic strategies for functional building units plays a central role in supramolecular chemistry. Both porphyrin and crown ethers have attracted the attention of researchers worldwide owing to their unique properties. It is envisioned that the integration of the two molecules will result in hybrid materials with potential applications in many fields. In the present study, a new porphyrin derivative 3 appended with four 18-crown-6 (18C6) ether moieties was synthesized through the Suzuki-Miyaura coupling of boronic ester porphyrin 1 and 4-bromobenzo-18-crown-6 2 in 80% yield. Porphyrin 3 was fully characterized by 1H/[Formula: see text]C NMR spectroscopy and high resolution mass spectrometry. The tendency of the 18C6 to form host-guest complexes with ammonium cations was exploited to assemble cation responsive hybrid material of porphyrin 3 and ammonium immobilized mesoporous silica nanoparticles (MSNs). Furthermore, the potential application of the 3/MSNs conjugate as a cation-responsive drug delivery vehicle was investigated in solution by UV-vis and fluorescence spectroscopies.


2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Emily C. Hartman ◽  
Christopher M. Jakobson ◽  
Andrew H. Favor ◽  
Marco J. Lobba ◽  
Ester Álvarez-Benedicto ◽  
...  

2019 ◽  
Vol 26 (5) ◽  
Author(s):  
Dinh Tien Dung Nguyen ◽  
Long Giang Bach ◽  
Thi Hiep Nguyen ◽  
Minh Hieu Ho ◽  
Minh Nhat Ho ◽  
...  

2015 ◽  
Vol 26 (8) ◽  
pp. 924-931 ◽  
Author(s):  
Feng Su ◽  
Jingzhao Wang ◽  
Shoujin Zhu ◽  
Shuilian Liu ◽  
Xiaoqin Yu ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (18) ◽  
pp. 14692-14704 ◽  
Author(s):  
Tilahun Ayane Debele ◽  
Shewaye Lakew Mekuria ◽  
Shuian-Yin Lin ◽  
Hsieh-Chih Tsai

HPC nanogels possess bright blue fluorescence which eliminates the use of additional probing agents in image-guided drug delivery. The results showed that disulfide crosslinked HPC nanogels are promising vehicles for stimulated photosensitizer delivery in advanced PDT.


2007 ◽  
Vol 118 (3) ◽  
pp. 275-284 ◽  
Author(s):  
Azadeh Kheirolomoom ◽  
Paul A. Dayton ◽  
Aaron F.H. Lum ◽  
Erika Little ◽  
Eric E. Paoli ◽  
...  

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