Preparation and characterization of oxaliplatin drug delivery vehicle based on PEGylated half-generation PAMAM dendrimer

2019 ◽  
Vol 26 (5) ◽  
Author(s):  
Dinh Tien Dung Nguyen ◽  
Long Giang Bach ◽  
Thi Hiep Nguyen ◽  
Minh Hieu Ho ◽  
Minh Nhat Ho ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Pamam Dendrimer ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

scholarly journals Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Emily C. Hartman ◽  
Christopher M. Jakobson ◽  
Andrew H. Favor ◽  
Marco J. Lobba ◽  
Ester Álvarez-Benedicto ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Single Amino Acid ◽  
Viral Capsid ◽  
Delivery Vehicle ◽  
Quantitative Characterization ◽  
Drug Delivery Vehicle ◽  
Amino Acid Variants

Synthesis and characterization of thiolated carboxymethyl chitosan-graft-cyclodextrin nanoparticles as a drug delivery vehicle for albendazole

2013 ◽  
Vol 24 (8) ◽  
pp. 1939-1949 ◽  
Author(s):  
Ghazaleh Alamdarnejad ◽  
Alireza Sharif ◽  
Shahrouz Taranejoo ◽  
Mohsen Janmaleki ◽  
Mohammad Reza Kalaee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Carboxymethyl Chitosan ◽  
Synthesis And Characterization ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

scholarly journals Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle

2007 ◽  
Vol 118 (3) ◽  
pp. 275-284 ◽  
Author(s):  
Azadeh Kheirolomoom ◽  
Paul A. Dayton ◽  
Aaron F.H. Lum ◽  
Erika Little ◽  
Eric E. Paoli ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle

Design and characterization of a multi‐layered polymeric drug delivery vehicle

2019 ◽  
Vol 97 (S1) ◽  
pp. 1243-1252
Author(s):  
Kei Xian Tan ◽  
Safina Ujan ◽  
Michael K. Danquah ◽  
Sie Yon Lau
Keyword(s):  
Drug Delivery ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Polymeric Drug Delivery ◽  
Polymeric Drug

Synthesis and Characterization of Polyethylene Glycol Modified Chitosan

2020 ◽  
Vol 859 ◽  
pp. 87-93
Author(s):  
Phenphak Prompanya ◽  
Supang Khondee
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Water Solubility ◽  
Biomedical Application ◽  
Entrapment Efficiency ◽  
Critical Aggregation Concentration ◽  
Delivery Vehicle ◽  
Drug Delivery Vehicle ◽  
Modified Chitosan

Chitosan (CS) is known for excellent biodegradability and low immunogenicity. However, its low water solubility has hampered CS biomedical application. In this study, we aimed to modify CS with polyethylene glycol (PEG) to improve water solubility and explored the possibility to use as a drug delivery vehicle. Degree of substitution of PEG on CS was varied, ranged from 16% to 78%. After dispersing in water, CS-PEG750 and CS-PEG5000 could spontaneously form small nanoaggreagtes (NGs) at low concentration, with critical aggregation concentration ranged from 32 μg/mL to 112 μg/mL. Upon encapsulation of curcumin, all NGs were slightly bigger in size. CS-PEG750 (1:40) NGs showed the highest entrapment efficiency at 59%, while CS-PEG5000 (1:40) and (1:60) NGs exhibited 36.9% and 36.5% entrapment efficiency, respectively. With few steps of modification, this modified CS copolymers reveal improved water solubility and decent entrapment efficiency. Thus this copolymer is a potential contender as a drug delivery vehicle.

Sign in / Sign up

Export Citation Format

Share Document