Psychological Flexibility, Pain Characteristics and Risk of Opioid Misuse in Noncancerous Chronic Pain Patients

2020 ◽  
Author(s):  
Amanda Rhodes ◽  
Donald Marks ◽  
Jennifer Block-Lerner ◽  
Timothy Lomauro
Keyword(s):  
Chronic Pain ◽  
Psychological Flexibility ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Characteristics ◽  
Pain Patients

Predicting Opioid Misuse by Chronic Pain Patients

2008 ◽  
Vol 24 (6) ◽  
pp. 497-508 ◽  
Author(s):  
Dennis C. Turk ◽  
Kimberly S. Swanson ◽  
Robert J. Gatchel
Keyword(s):  
Chronic Pain ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals Translation, Cultural Adaptation and Validation of the Current Opioid Misuse Measure for European Portuguese

2020 ◽  
Vol 33 (4) ◽  
pp. 261
Author(s):  
Diogo Mendes-Morais ◽  
Cláudia Jantarada ◽  
Luís Guimarães-Pereira
Keyword(s):  
Chronic Pain ◽  
Principal Components ◽  
Cultural Adaptation ◽  
Good Practice ◽  
Opioid Misuse ◽  
Cronbach’S Alpha ◽  
Intra Class Correlation ◽  
Cronbach's Alpha ◽  
Chronic Pain Patients ◽  
Pain Patients

Introduction: Current practice guidelines recommend using Current Opioid Misuse Measure to screen aberrant opioid-related behaviors in chronic pain patients. Our aims were to translate, adapt and validate it to be used in Portuguese chronic pain patients.Material and Methods: Translation and cultural adaptation process followed guidelines and a model of principles for good practice. Adult chronic pain patients on opioid therapy, from one major hospital in Portugal, were invited to complete the translated version. Descriptive statistics, Cronbach’s alpha, inter-item, item-total and intra-class correlation coefficients and principal components analysis were applied.Results: Translation process was performed as planned and the validation sample was composed by 98 patients (median age = 62.5 years). Regarding internal consistency, a global Cronbach’s alpha of 0.778 was obtained and item-total correlations of all items were above 0.20 with four exceptions. An intra-class correlation coefficient of 0.90 was found between test and retest. Regarding validity, all 17 items presented a content validity index above 0.80. Six principal components were extracted and explained 66.3% of the variance.Discussion: The Portuguese version of Current Opioid Misuse Measure was properly translated, adapted and validated; showing good quality in terms of reliability and validity. This is the first instrument to screen aberrant opioid-related behaviors in Portuguese chronic pain patients. Consequently, it will aid and promote the identification of opioid misuse in these patients.Conclusion: The implementation of this questionnaire may reduce the incidence and morbimortality of opioid misuse among chronic pain patients and should improve chronic pain treatment in Portugal.

scholarly journals Cross Validation of the Current Opioid Misuse Measure to Monitor Chronic Pain Patients on Opioid Therapy

2010 ◽  
Vol 26 (9) ◽  
pp. 770-776 ◽  
Author(s):  
Stephen F. Butler ◽  
Simon H. Budman ◽  
Gilbert J. Fanciullo ◽  
Robert N. Jamison
Keyword(s):  
Chronic Pain ◽  
Cross Validation ◽  
Opioid Therapy ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Patients

(435) Reducing opioid misuse among chronic pain patients in primary care

2015 ◽  
Vol 16 (4) ◽  
pp. S84
Author(s):  
D. Jurcik ◽  
E. Ross ◽  
E. Scanlan ◽  
R. Jamison ◽  
M. Matthews
Keyword(s):  
Primary Care ◽  
Chronic Pain ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals Association between Neuropathic Pain Characteristics and DNA Methylation of TRPA1 in Human Peripheral Blood

2019 ◽  
Author(s):  
Shiho Takenaka ◽  
Norihiko Sukenaga ◽  
Mai Imasaka ◽  
Masaki Ohmuraya ◽  
Yuka Matsuki ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Chronic Pain ◽  
Neuropathic Pain ◽  
Peripheral Blood ◽  
Transient Receptor Potential ◽  
Cpg Island ◽  
Human Peripheral Blood ◽  
Chronic Pain Patients ◽  
Pain Characteristics ◽  
Pain Patients

Background: Elucidation of epigenetic mechanisms correlating with neuropathic pain in humans is crucial for the prevention and treatment of this treatment-resistant pain state. In the present study, associations between neuropathic pain characteristics and DNA methylation of the transient receptor potential ankyrin 1(TRPA1) gene were evaluated in chronic pain patients and preoperative patients. Methods: Pain and psychological states were prospectively assessed in patients who suffered chronic pain or were scheduled for thoracic surgery. Neuropathic characteristics were assessed using the Douleur Neuropathique 4 (DN4) questionnaire. DNA methylation levels of the CpG island in the TRPA1 gene were examined using whole blood. Results: Forty-eight adult patients were enrolled in this study. Increases in DNA methylation rates at CpG -51 showed positive correlations with increases in the DN4 score both in preoperative and chronic pain patients. Combined methylation rates at CpG -51 also significantly increased together with increase in DN4 scores. Conclusions: Neuropathic pain characteristics are likely associated with methylation rates at the promoter region of the TRPA1 gene in human peripheral blood.

Chronic Pain Patients with and without Alexithymia*

1988 ◽  
Vol 33 (9) ◽  
pp. 830-833 ◽  
Author(s):  
Santosh K. Chaturvedi
Keyword(s):  
Chronic Pain ◽  
Psychiatric Diagnosis ◽  
Demographic Variables ◽  
Physical Illness ◽  
Study Group ◽  
Control Groups ◽  
Chronic Pain Patients ◽  
Pain Characteristics ◽  
Pain Patients

Chronic pain patients with and without alexithymia have been compared, but no differences were observed as regards demographic variables or pain characteristics. More alexithymic patients had associated physical illness and this was significantly (P < 0.05) different from the control groups. Psychiatric diagnosis was ascribed to only three alexithymic pain patients. It is likely that verbal inexpressivity interferes with the emergence of psychopathology. Lower level of psychopathology could be due to the marked alexithymia in the pain patients of the study group.

scholarly journals Cross-Validation of a Screener to Predict Opioid Misuse in Chronic Pain Patients (SOAPP-R)

2009 ◽  
Vol 3 (2) ◽  
pp. 66-73 ◽  
Author(s):  
Stephen F. Butler ◽  
Simon H. Budman ◽  
Kathrine C. Fernandez ◽  
Gilbert J. Fanciullo ◽  
Robert N. Jamison
Keyword(s):  
Chronic Pain ◽  
Cross Validation ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals Behavioral preference for viewing drug v. pleasant images predicts current and future opioid misuse among chronic pain patients

2019 ◽  
Vol 50 (4) ◽  
pp. 644-652 ◽  
Author(s):  
Scott J. Moeller ◽  
Adam W. Hanley ◽  
Eric L. Garland
Keyword(s):  
Chronic Pain ◽  
Choice Behavior ◽  
Longitudinal Design ◽  
Choice Task ◽  
Prescription Opioid ◽  
Opioid Misuse ◽  
Chronic Pain Patients ◽  
Pain Patients ◽  
Insight Into

AbstractBackgroundThe USA is currently enduring an opioid crisis. Identifying cost-effective, easy-to-implement behavioral measures that predict treatment outcomes in opioid misusers is a crucial scientific, therapeutic, and epidemiological goal.MethodsThe current study used a mixed cross-sectional and longitudinal design to test whether a behavioral choice task, previously validated in stimulant users, was associated with increased opioid misuse severity at baseline, and whether it predicted change in opioid misuse severity at follow-up. At baseline, data from 100 prescription opioid-treated chronic pain patients were analyzed; at follow-up, data were analyzed in 34 of these participants who were non-misusers at baseline. During the choice task, participants chose under probabilistic contingencies whether to view opioid-related images in comparison with affectively pleasant, unpleasant, and neutral images. Following previous procedures, we also assessed insight into choice behavior, operationalized as whether (yes/no) participants correctly self-reported the image category they chose most often.ResultsAt baseline, the higher choice for viewing opioid images in direct comparison with pleasant images was associated with opioid misuse and impaired insight into choice behavior; the combination of these produced especially elevated opioid-related choice behavior. In longitudinal analyses of individuals who were initially non-misusers, higher baseline opioid v. pleasant choice behavior predicted more opioid misuse behaviors at follow-up.ConclusionsThese results indicate that greater relative allocation of behavior toward opioid stimuli and away from stimuli depicting natural reinforcement is associated with concurrent opioid misuse and portends vulnerability toward future misuse. The choice task may provide important medical information to guide opioid-prescribing practices.

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