scholarly journals How Do Pain Characteristics, Comorbidity Severity and Patient Characteristics Influence Chronic Pain Patients’ Self-Management Priorities?

Author(s):  
Marie-Eve Martel ◽  
Chrystelle El-Khoury ◽  
M Gabrielle Pagé
Author(s):  
Shiho Takenaka ◽  
Norihiko Sukenaga ◽  
Mai Imasaka ◽  
Masaki Ohmuraya ◽  
Yuka Matsuki ◽  
...  

Background: Elucidation of epigenetic mechanisms correlating with neuropathic pain in humans is crucial for the prevention and treatment of this treatment-resistant pain state. In the present study, associations between neuropathic pain characteristics and DNA methylation of the transient receptor potential ankyrin 1(TRPA1) gene were evaluated in chronic pain patients and preoperative patients. Methods: Pain and psychological states were prospectively assessed in patients who suffered chronic pain or were scheduled for thoracic surgery. Neuropathic characteristics were assessed using the Douleur Neuropathique 4 (DN4) questionnaire. DNA methylation levels of the CpG island in the TRPA1 gene were examined using whole blood. Results: Forty-eight adult patients were enrolled in this study. Increases in DNA methylation rates at CpG -51 showed positive correlations with increases in the DN4 score both in preoperative and chronic pain patients. Combined methylation rates at CpG -51 also significantly increased together with increase in DN4 scores. Conclusions: Neuropathic pain characteristics are likely associated with methylation rates at the promoter region of the TRPA1 gene in human peripheral blood.


1988 ◽  
Vol 33 (9) ◽  
pp. 830-833 ◽  
Author(s):  
Santosh K. Chaturvedi

Chronic pain patients with and without alexithymia have been compared, but no differences were observed as regards demographic variables or pain characteristics. More alexithymic patients had associated physical illness and this was significantly (P < 0.05) different from the control groups. Psychiatric diagnosis was ascribed to only three alexithymic pain patients. It is likely that verbal inexpressivity interferes with the emergence of psychopathology. Lower level of psychopathology could be due to the marked alexithymia in the pain patients of the study group.


2009 ◽  
Vol 10 (4) ◽  
pp. S5 ◽  
Author(s):  
E. Chiauzzi ◽  
S.Wing Venuti ◽  
K. Zacharoff

Pain ◽  
1987 ◽  
Vol 30 ◽  
pp. S416 ◽  
Author(s):  
J. M. Romano ◽  
J. A. Turner ◽  
K. L. Svriala ◽  
R. L. Levy

Medicine ◽  
2021 ◽  
Vol 100 (25) ◽  
pp. e26500
Author(s):  
Yoichi Tanaka ◽  
Hayato Shigetoh ◽  
Gosuke Sato ◽  
Ren Fujii ◽  
Ryota Imai ◽  
...  

2015 ◽  
Vol 20 (2) ◽  
pp. 75-83 ◽  
Author(s):  
Anaïs Lacasse ◽  
Patricia Bourgault ◽  
Yannick Tousignant-Laflamme ◽  
Roxanne Courtemanche-Harel ◽  
Manon Choinière

BACKGROUND: Perceived self-efficacy is a non-negligible outcome when measuring the impact of self-management interventions for chronic pain patients. However, no validated, chronic pain-specific self-efficacy scales exist for studies conducted with French-speaking populations.OBJECTIVES: To establish the validity of the use of the French-Canadian Chronic Pain Self-efficacy Scale (FC-CPSES) among chronic pain patients.METHODS: The Chronic Disease Self-Efficacy Scale is a validated 33-item self-administered questionnaire that measures perceived self-efficacy to perform self-management behaviours, manage chronic disease in general and achieve outcomes (a six-item version is also available). This scale was adapted to the context of chronic pain patients following cross-cultural adaptation guidelines. The FC-CPSES was administered to 109 fibromyalgia and 34 chronic low back pain patients (n=143) who participated in an evidence-based self-management intervention (the PASSAGE program) offered in 10 health care centres across the province of Quebec. Cronbach’s alpha coefficients (α) were calculated to determine the internal consistency of the 33- and six-item versions of the FC-CPSES. With regard to convergent construct validity, the association between the FC-CPSES baseline scores and related clinical outcomes was examined. With regard to the scale’s sensitivity to change, pre- and postintervention FC-CPSES scores were compared.RESULTS: Internal consistency was high for both versions of the FC-CPSES (α=0.86 to α=0.96). Higher self-efficacy was significantly associated with higher mental health-related quality of life and lower pain intensity and catastrophizing (P<0.05), supporting convergent validity of the scale. There was a statistically significant increase in FC-CPSES scores between pre- and postintervention measures for both versions of the FC-CPSES (P<0.003), which supports their sensitivity to clinical change during an intervention.CONCLUSIONS: These data suggest that both versions of the FC-CPSES are reliable and valid for the measurement of pain management self-efficacy among chronic pain patients.


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