Biologically Active Water Soluble Novel Biopolymer/Hydrazide Based O-Carboxymethyl Chitosan Schiff Bases: Synthesis and Characterisation

2020 ◽  
Vol 30 (9) ◽  
pp. 3658-3676 ◽  
Author(s):  
Murugaiyan Manimohan ◽  
Sivashanmugam Pugalmani ◽  
Mohamed Aboobucker Sithique
Keyword(s):  
Schiff Bases ◽  
Carboxymethyl Chitosan ◽  
Water Soluble ◽  
Biologically Active ◽  
Chitosan Schiff Bases

Zinc(ii) centered biologically active novel N,N,O donor tridentate water-soluble hydrazide-based O-carboxymethyl chitosan Schiff base metal complexes: synthesis and characterisation

2019 ◽  
Vol 43 (24) ◽  
pp. 9540-9554 ◽  
Author(s):  
Manimohan Murugaiyan ◽  
S. Pugal Mani ◽  
Mohamed Aboobucker Sithique
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Carboxymethyl Chitosan ◽  
Water Soluble ◽  
Biologically Active ◽  
Schiff Base Derivatives ◽  
Schiff Base Metal Complexes ◽  
Potential Use ◽  
Chitosan Schiff Base

In this study, novel eco-friendly and water-soluble chitosan Schiff base derivatives have been designed for potential use in antimicrobial applications.

The content of decenoic acids in drone brood preparations and combined preparations based on it

Biomics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 389-393
Author(s):  
D.V. Mitrofanov ◽  
N.V. Budnikova
Keyword(s):  
Royal Jelly ◽  
Storage Conditions ◽  
Water Soluble ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Strict Adherence ◽  
Drone Brood ◽  
Wide Range ◽  
Active Substances ◽  
Melanin Complex

The drone brood contains a large number of substances with antioxidant activity. These substances require stabilization and strict adherence to storage conditions. Among these substances are unique decenoic acids, the content of which is an indicator of the quality of drone brood and products based on it. The ability of drone brood to reduce the manifestations of oxidative stress is shown. There are dietary supplements for food and drugs based on drone brood, which are used for a wide range of diseases. Together with drone brood, chitosan-containing products, propolis, royal jelly can be used. They enrich the composition with their own biologically active substances and affect the preservation of the biologically active substances of the drone brood. Promising are the products containing, in addition to the drone brood, a chitin-chitosan-melanin complex from bees, propolis, royal jelly. The chitin-chitosan-melanin complex in the amount of 5% in the composition of the adsorbent practically does not affect the preservation of decenic acids, while in the amount of 2% and 10% it somewhat worsens. The acid-soluble and water-soluble chitosan of marine crustaceans significantly worsens the preservation of decenoic acids in the product. Drone brood with royal jelly demonstrates a rather high content of decenoic acids. When propolis is introduced into the composition of the product, the content of decenoic acids increases according to the content of propolis.

scholarly journals Solid Dispersions of Anthelmintics and Plant Protection Preparations

Solids ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 60-75
Author(s):  
Salavat S. Khalikov
Keyword(s):  
Plant Protection ◽  
Rapid Development ◽  
Solid Dispersions ◽  
Animal Health ◽  
Water Soluble ◽  
Biologically Active ◽  
Cultivated Plants ◽  
Industrial Complex ◽  
Scientific Papers ◽  
Poorly Soluble

Because of the rapid development of nanotechnologies, materials, in particular, solid dispersions (SDs), which are actively introduced into the life of modern man, have been obtained. Special progress in this area is observed in industry and medicine. The use of SDs in agriculture is lagging far behind, despite the growing number of scientific papers on this topic. At the same time, the prospects for the introduction of SDs in the agro-industrial complex are obvious. The review presents the results of research on the development of innovative preparations based on SD to protect plants from diseases and pests of cultivated plants, as well as parasiticides to protect animal health based on modern achievements of nanotechnology. One of these technologies is the methods of mechanochemistry, which improve the properties of poorly soluble biologically active substances by their joint mechanical treatment with water-soluble polymers and auxiliary substances.

scholarly journals Synthesis and Evaluation of Schiff Bases of 4-Amino-5-(chlorine substituted phenyl)-4H-1,2,4-triazole-3-thione as Antimicrobial Agents

2020 ◽  
Vol 41 (1) ◽  
pp. 26-35
Author(s):  
Kishor Devkota ◽  
Govinda Pathak ◽  
Bhushan Shakya
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Triazole Ring ◽  
Antimicrobial Activities ◽  
Biologically Active ◽  
Spectral Techniques ◽  
Schiff Base Derivatives ◽  
Bacteria And Fungi ◽  
Different Strains

Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems. Schiff bases are also considered as one of the most biologically active compounds.  The aim of the present study was to synthesize new Schiff bases bearing triazole nucleus and to assess their antimicrobial activities. Four new Schiff base derivatives of 1,2,4-triazole-3-thione were synthesized by combining two different pharmacophores viz. triazole nucleus and Schiff base moiety and were characterized by spectral techniques (UV, FT-IR, and NMR). The Schiff bases were evaluated for antibacterial (Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae) and antifungal (Candida albicans) activities. The synthesized compounds exhibited good to moderate activities against different strains of bacteria and fungi tested.

scholarly journals Assessing protopectin transformation potential of plant tissue using a zoned criterion space

2020 ◽  
Vol 8 (2) ◽  
pp. 349-361
Author(s):  
Vladimir Kondratenko ◽  
Tatyana Kondratenko ◽  
Andrey Petrov ◽  
Georgy Belozerov
Keyword(s):  
Boundary Conditions ◽  
Plant Tissue ◽  
Raw Materials ◽  
Water Soluble ◽  
Biologically Active ◽  
Plant Raw Materials ◽  
Criterion Space ◽  
Transformation Potential ◽  
Fragmentation Potential ◽  
Pectin Substances

Introduction. The existing diversity of plant raw materials and products predetermine the prospects of studying their potential as sources of pectin substances. However all current classifications are either fragmented or inconsistent. Study objects and methods. Our theoretical ivestigation aimed to develop an adequate classification for all taxa of plant origin, as well as their tissues and derivatives as pectin-containing materials. We developed criteria for assessing transformation potential of the protopectin complex based on the mass fractions of biologically active non-uronide components, native water-soluble pectin, the protopectin complex, and pectin substances. Individual boundary conditions were based on individual pectin potential, protopectin fragmentation potential, and pectin isolation potential. Results and discussion. Based on the boundary conditions, we defined an universal criterion space that included a set of points M in the coordinates expressed by three main criteria. According to individual boundary conditions, the criterion space was divided, or zoned, into four domains corresponding to protopectin fragmentation potential. They were characterized by: 1) lack of pectin potential, 2) ineffective protopectin fragmentation, 3) ineffective isolation of fragmentation products, and 4) effective isolation. Finally, we developed a generalized algorithm to determine the location of points M[μ1, μ2 , μ3 ] in the zoned criterion space, characterizing the plant tissue. Conclusion. Our approach can be used to assess any plant tissue for its protopectin transformation potential, which determines the technological influence on its pectin potential. This approach is universal, i.e., applicable to both plant tissue and its derivatives.

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