Biologically active novel N, N, O donor tridentate water soluble hydrazide based O-carboxymethyl chitosan Schiff base Cu (II) metal complexes: Synthesis and characterisation

2019 ◽  
Vol 136 ◽  
pp. 738-754 ◽  
Author(s):  
Murugaiyan Manimohan ◽  
Sivashanmugam Pugalmani ◽  
Mohamed Aboobucker Sithique
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Carboxymethyl Chitosan ◽  
Water Soluble ◽  
Biologically Active ◽  
Chitosan Schiff Base

Zinc(ii) centered biologically active novel N,N,O donor tridentate water-soluble hydrazide-based O-carboxymethyl chitosan Schiff base metal complexes: synthesis and characterisation

2019 ◽  
Vol 43 (24) ◽  
pp. 9540-9554 ◽  
Author(s):  
Manimohan Murugaiyan ◽  
S. Pugal Mani ◽  
Mohamed Aboobucker Sithique
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Carboxymethyl Chitosan ◽  
Water Soluble ◽  
Biologically Active ◽  
Schiff Base Derivatives ◽  
Schiff Base Metal Complexes ◽  
Potential Use ◽  
Chitosan Schiff Base

In this study, novel eco-friendly and water-soluble chitosan Schiff base derivatives have been designed for potential use in antimicrobial applications.

scholarly journals Synthesis of Mn(II) Complexes-Carboxymethyl Chitosan Schiff Base Salicylaldehyde and Antibacterial Activity

2021 ◽  
Vol 7 (1) ◽  
pp. 10-21
Author(s):  
Ismiyarto Ismiyarto ◽  
Niken Windi Saputri ◽  
Liswinda Zafirah Rahmatia ◽  
Purbowatiningrum Ria Sarjono ◽  
Ngadiwiyana Ngadiwiyana ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Schiff Base ◽  
Carboxymethyl Chitosan ◽  
Diffusion Method ◽  
Clear Zone ◽  
Disc Diffusion Method ◽  
Zone Diameter ◽  
Chitosan Schiff Base

The development of compounds with a better antibacterial activity is highly needed. One way to achieve this is by modifying the structure of the compound using chitosan as a starting material, because of its abundant natural source in Indonesia, its biodegradable properties, and its structure where free amines are present. This study aims to obtain  Mn(II) -Carboxymethyl Chitosan Schiff Base-Salicylaldehyde complex to increase its antibacterial activity against Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative). Schiff Base carboxymethyl chitosan-salicylaldehyde was synthesized from carboxymethyl chitosan with salicylaldehyde. Next, the Schiff Base Carboxymethyl Chitosan-Salicylaldehyde was complexed with MnCl2.4H2O and then characterized by FTIR, UV-Vis Spectrophotometer, and AAS and tested for antibacterial activity with the disc diffusion method against Staphylococcus aureus and Escherichia coli. The product of Carboxymethyl Chitosan Schiff Base-salicylaldehyde is a brownish yellow solid with a yield of 64% (w/w) and has antibacterial activity against Staphylococcus aureus (clear zone diameter 11 mm) and Escherichia coli (clear zone diameter 13 mm). The product of Mn(II) Complexes-Carboxymethyl Chitosan Schiff Base-salicylaldehyde is a black solid with a yield of 59% (w/w) and has antibacterial activity against Staphylococcus aureus (clear zone diameter 13 mm) and Escherichia coli (clear zone diameter 17 mm).

scholarly journals Synthesis and Anticancer Activities of Water Soluble Schiff Base Metal Complexes

2020 ◽  
Author(s):  
Burcu SAYGIDEĞER DEMİR ◽  
İlyas GÖNÜL ◽  
Gizem GÜMÜŞGÖZ ÇELİK ◽  
Seda İPEKBAYRAK ◽  
Yasemin SAYGIDEĞER
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Water Soluble ◽  
Anticancer Activities ◽  
Schiff Base Metal Complexes

In Vitro Evaluation of Antifungal Activities by Permeation of Ru(III) Complexes Derived from Chitosan-Schiff Base Ligand

2020 ◽  
Vol 3 (3) ◽  
pp. 212-220
Author(s):  
T. Vadivel ◽  
M. Dhamodaran ◽  
S. Kulathooran ◽  
M. Kavitha ◽  
K. Amirthaganesan
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Diffusion Method ◽  
Bidentate Ligands ◽  
Antifungal Activities ◽  
Study Results ◽  
Chitosan Schiff Base

Background: The transition metal complexes are derived from a natural biopolymer which is a very potent material in various research areas of study. Objective: This study aims to show the preparation of ruthenium(III) complexes from chitosan Schiff base ligand for effective application in antifungal studies. Methods: Chemical modification was carried out through a condensation reaction of chitosan with some aromatic aldehydes, which resulted in the formation of a bidentate Schiff base ligand. The Ru(III) complexes were prepared by complexation of ruthenium metal ion with bidentate ligands. The series of Ru(III) complexes were characterized by Scanning Electron Microscope with Electron dispersive X-ray (SEM-EDX) analysis, Powder XRD. The biopolymer-based transition metal complexes have potential uses for their biological activities. The synthesized metal complexes were directed for antifungal study by the disc diffusion method. Results: The antifungal study results showed that the transition metal complexes have significant antifungal activities against some vital fungal pathogens such as Aspergillus flavus, Aspergillus niger, Fusarium oxysporum, Penicillim chryogenum and Trigoderma veride. Conclusion: A chitosan biopolymer offers some peculiar features such as biodegradability, biocompatibility etc., which are favorable for green synthesis of transition metal complexes through complexation with bidentate ligands. These metal complexes possess good antifungal property due to their chelation effect on micro-organisms.

scholarly journals Applications of Chitosan Based Schiff bases and its Complexes – A Review

2021 ◽  
pp. 157-170
Author(s):  
Veena R Nair ◽  
Meera Jacob ◽  
Texin Joseph ◽  
Jaya T Varkey
Keyword(s):  
Schiff Base ◽  
Metal Ions ◽  
Metal Complexes ◽  
Schiff Bases ◽  
Schiff Base Complexes ◽  
Amino Group ◽  
Chemical Modifications ◽  
Research Fields ◽  
Chitosan Schiff Base ◽  
Chitosan Schiff Bases

Chitosan, a natural polysaccharides biopolymer is a versatile and promising biomaterial. Chitosan metal complexes stand out in their applicability in different research fields due to their biocompatibility and biodegradability properties. Presence of primary aliphatic amino group along the polymer chain allows for a variety of chemical modifications, of which the most significant is imine functionalization. The ability to easily perform complexation between chitosan Schiff bases and metal ions results in metal complexes, enhancing its application, resulting in further innovation in various fields. The most recent advances of chitosan Schiff base complexes in various fields, including biomedical, catalysis, environmental, and adsorption are summarised in this review.

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