Development of Graphene Oxide Nanosheets as Potential Biomaterials in Cancer Therapeutics: An In-Vitro Study Against Breast Cancer Cell Line

2021 ◽  
Author(s):  
Yugal Kishore Mohanta ◽  
Kunal Biswas ◽  
Pradipta Ranjan Rauta ◽  
Awdhesh Kumar Mishra ◽  
Debashis De ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Graphene Oxide ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
In Vitro Study ◽  
Cancer Therapeutics ◽  
Graphene Oxide Nanosheets

scholarly journals Improving the Efficacy of Cisplatin using Niosome Nanoparticles Against Human Breast Cancer Cell Line BT-20 : An In Vitro Study

2017 ◽  
Vol 2 (2) ◽  
pp. 27-29 ◽  
Author(s):  
Leila Kanaani ◽  
Maral Mazloumi Tabrizi ◽  
Azim Akbarzadeh Khiyavi ◽  
Iraj Javadi
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
In Vitro Study ◽  
Initial Response ◽  
Lethal Effect

Objective: Today, cancer is one the most important challenges in modern medicine. Meanwhile, breast cancer is one of the most common causes of mortality among cancers. The initial response to the treatment and then becoming resistant to the cisplatin is one of basal challenges of treatment of breast cancer. Recently, using nanotechnology including drug nanocarrier named niosome can decrease adverse effects and increase the efficiency of treatment. Material and Methods: The aim of this research was to investigate using niosome nanoparticles containing cisplatin and investigation of their lethal effect on breast cancer cell line. Results: We found that using niosome nanoparticles can provide a suitable formulation of cisplatin drug. Conclusion: The efficiency of nanoniosome cisplatin was more than free drug, decreasing the administered dose and therefore the damage to other tissues.

scholarly journals The Effect of Nano-Transferosomal Hydroxyurea on 4T1 animal Breast Cancer Cell Line: An in Vitro Study

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Maral Mazloumi Tabrizi ◽  
Pouria Mohammadi ◽  
Afrooz Ahmadi ◽  
Mohammadreza Malekpour ◽  
Nahid Kabiry ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
In Vitro Study ◽  
Vitro Study

The role of captopril and losartan in prevention and regression of tamoxifen-induced resistance of breast cancer cell line MCF-7: An in vitro study

2014 ◽  
Vol 68 (5) ◽  
pp. 565-571 ◽  
Author(s):  
Soha Namazi ◽  
Javad Rostami-Yalmeh ◽  
Ebrahim Sahebi ◽  
Mansooreh Jaberipour ◽  
Mahboobeh Razmkhah ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Induced Resistance ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
In Vitro Study ◽  
Mcf 7

scholarly journals THE EFFECT OF AQUEOUS EXTRACTS OF NIGELLA SATIVA ON BREAST CANCER CELL LINE MCF-7: AN IN VITRO STUDY

2018 ◽  
Vol 2 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Muhammad Solehuddin Bumidin ◽  
Farah Azurin Johari ◽  
Nurul Fikri Risan ◽  
Mohd Hamzah Mohd Nasir
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Nigella Sativa ◽  
Cancer Cell Line ◽  
In Vitro Study ◽  
Aqueous Extracts ◽  
Mcf 7

scholarly journals Formulation of Piperine–Chitosan-Coated Liposomes: Characterization and In Vitro Cytotoxic Evaluation

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3281
Author(s):  
Syed Sarim Imam ◽  
Sultan Alshehri ◽  
Mohammad A. Altamimi ◽  
Afzal Hussain ◽  
Wajhul Qamar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Therapeutic Efficacy ◽  
Cancer Cell Line ◽  
Permeation Study ◽  
Study Results

The present research work is designed to prepare and evaluate piperine liposomes and piperine–chitosan-coated liposomes for oral delivery. Piperine (PPN) is a water-insoluble bioactive compound used for different diseases. The prepared formulations were evaluated for physicochemical study, mucoadhesive study, permeation study and in vitro cytotoxic study using the MCF7 breast cancer cell line. Piperine-loaded liposomes (PLF) were prepared by the thin-film evaporation method. The selected liposomes were coated with chitosan (PLFC) by electrostatic deposition to enhance the mucoadhesive property and in vitro therapeutic efficacy. Based on the findings of the study, the prepared PPN liposomes (PLF3) and chitosan coated PPN liposomes (PLF3C1) showed a nanometric size range of 165.7 ± 7.4 to 243.4 ± 7.5, a narrow polydispersity index (>0.3) and zeta potential (−7.1 to 29.8 mV). The average encapsulation efficiency was found to be between 60 and 80% for all prepared formulations. The drug release and permeation study profile showed biphasic release behavior and enhanced PPN permeation. The in vitro antioxidant study results showed a comparable antioxidant activity with pure PPN. The anticancer study depicted that the cell viability assay of tested PLF3C2 has significantly (p < 0.001)) reduced the IC50 when compared with pure PPN. The study revealed that oral chitosan-coated liposomes are a promising delivery system for the PPN and can increase the therapeutic efficacy against the breast cancer cell line.

Gas chromatography-mass spectrometry fingerprint and in vitro cytotoxic studies of Rubus steudneri leaf fractions against michigan cancer foundation-7 breast cancer cell line

2021 ◽  
Vol 17 (5) ◽  
pp. 54
Author(s):  
RaghavendraLakshmana Shetty Hallur ◽  
ChaitanyaV. N L. Motamarri ◽  
PrashithKekuda T. Ramamoorthy ◽  
ChetanD Murthy ◽  
RavikumarPatil H. Siddappa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Cell Line ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Gas Chromatography Mass Spectrometry ◽  
Cytotoxic Studies
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