Predicting the Onset of Sexual and Drug Risk Behaviors in HIV-Negative Youths with HIV-Positive Mothers: The Role of Contextual, Self-Regulation, and Social-Interaction Factors

2006 ◽  
Vol 36 (3) ◽  
pp. 265-278 ◽  
Author(s):  
Claude A. Mellins ◽  
Curtis Dolezal ◽  
Elizabeth Brackis-Cott ◽  
Ouzama Nicholson ◽  
Patricia Warne ◽  
...  
Keyword(s):  
Social Interaction ◽  
Risk Behaviors ◽  
Self Regulation ◽  
Hiv Positive ◽  
Drug Risk ◽  
Hiv Positive Mothers ◽  
Interaction Factors ◽  
Hiv Negative

scholarly journals Tubercular meningitis with hydrocephalus with HIV co-infection: role of cerebrospinal fluid diversion procedures

2015 ◽  
Vol 122 (5) ◽  
pp. 1087-1095 ◽  
Author(s):  
Raman Mohan Sharma ◽  
Nupur Pruthi ◽  
Arivazhagan Arimappamagan ◽  
Sampath Somanna ◽  
Bhagavathula Indira Devi ◽  
...  
Keyword(s):  
Hiv Positive ◽  
Short Term ◽  
Tubercular Meningitis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Shunt Placement ◽  
Poor Outcome ◽  
Hiv Negative

OBJECT Hydrocephalus is one of the commonest complications of tubercular meningitis (TBM), and its incidence is increasing with the HIV epidemic. Literature evaluating the role of ventriculoperitoneal shunts in HIV-positive patients with TBM and their long-term prognosis is scarce. METHODS Between June 2002 and October 2012, 30 HIV-positive patients with TBM and hydrocephalus underwent ventriculoperitoneal shunt placement. Thirty age-, sex-, and grade-matched HIV-negative patients with TBM and hydrocephalus were randomly selected as the control group. Outcome was analyzed at discharge (short-term outcome) and at follow-up (long-term outcome). Univariate and multivariate analyses were performed to look for predictors of outcome; p < 0.05 was considered significant. RESULTS There were no differences in the clinical, radiological, or biochemical parameters between the 2 groups. Short-term outcome was better in the HIV-negative group (76.7% improvement) than in the HIV-positive group (70%). However, the long-term outcome in HIV-positive patients was very poor (66.7% mortality and 76.2% poor outcome) compared with HIV-negative patients (30.8% mortality and 34.6% poor outcome). Seropositivity for HIV is an independent predictor of poor outcome both in univariate and multivariate analyses (p = 0.038). However, in contrast to previous reports, of 5 patients with TBM in good Palur grades among the HIV-positive patients, 4 (80%) had good outcome following shunt placement. CONCLUSIONS The authors recommend that shunt treatment should not be performed in HIV-positive patients in poor Palur grade with hydrocephalus. A trial of external ventricular drainage should be undertaken in such patients, and shunt treatment should be performed only if there is any improvement. However, HIV-positive patients in good Palur grades should undergo VP shunt placement, as these patients have better outcomes than previously reported.

scholarly journals Relationship between the Cervical Microbiome, HIV Status, and Precancerous Lesions

mBio ◽  
2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Cameron Klein ◽  
Daniela Gonzalez ◽  
Kandali Samwel ◽  
Crispin Kahesa ◽  
Julius Mwaiselage ◽  
...  
Keyword(s):  
Hiv Positive ◽  
High Grade ◽  
Squamous Intraepithelial Lesions ◽  
Cervical Lesions ◽  
Cervical Cancers ◽  
Bacterial Microbiome ◽  
Bacterial Richness ◽  
Intraepithelial Lesions ◽  
Hiv Negative

ABSTRACT Nearly all cervical cancers are causally associated with human papillomavirus (HPV). The burden of HPV-associated dysplasias in sub-Saharan Africa is influenced by HIV. To investigate the role of the bacterial microbiome in cervical dysplasia, cytobrush samples were collected directly from cervical lesions of 144 Tanzanian women. The V4 hypervariable region of the 16S rRNA gene was amplified and deep sequenced. Alpha diversity metrics (Chao1, PD whole tree, and operational taxonomic unit [OTU] estimates) displayed significantly higher bacterial richness in HIV-positive patients (P = 0.01) than in HIV-negative patients. In HIV-positive patients, there was higher bacterial richness in patients with high-grade squamous intraepithelial lesions (HSIL) (P = 0.13) than those without lesions. The most abundant OTUs associated with high-grade squamous intraepithelial lesions were Mycoplasmatales, Pseudomonadales, and Staphylococcus. We suggest that a chronic mycoplasma infection of the cervix may contribute to HPV-dependent dysplasia by sustained inflammatory signals. IMPORTANCE HPV is known to be the causal agent in the majority of cervical cancers. However, the role of the cervical bacterial microbiome in cervical cancer is not clear. To investigate that possibility, we collected cervical cytobrush samples from 144 Tanzanian women and performed deep sequencing of bacterial 16S rRNA genes. We found that HIV-positive patients had greater bacterial richness (P = 0.01) than HIV-negative patients. We also observed that women with high-grade squamous intraepithelial lesions (HSIL) had greater cervical bacterial diversity than women with cytologically normal cervices. Data from our precise sampling of cervical lesions leads us to propose that Mycoplasma contributes to a cervical microbiome status that promotes HPV-related cervical lesions. These results suggest a greater influence of the bacterial microbiota on the outcome of HPV infection than previously thought.

The Role of Supportive Housing for HIV-Positive Mothers and Their Children

2015 ◽  
Vol 41 (5) ◽  
pp. 642-658 ◽  
Author(s):  
Katherine Quinn ◽  
Staci Young ◽  
Dave Thomas ◽  
Brennan Baldwin ◽  
Melanie Paul
Keyword(s):  
Supportive Housing ◽  
Hiv Positive ◽  
Hiv Positive Mothers

scholarly journals Cardiac Effects of Antiretroviral Therapy in HIV-Negative Infants Born to HIV-Positive Mothers

2011 ◽  
Vol 57 (1) ◽  
pp. 76-85 ◽  
Author(s):  
Steven E. Lipshultz ◽  
William T. Shearer ◽  
Bruce Thompson ◽  
Kenneth C. Rich ◽  
Irene Cheng ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Hiv Positive ◽  
Cardiac Effects ◽  
Hiv Positive Mothers ◽  
Hiv Negative

Transmission risk behaviors in a subset of HIV-positive individuals: The role of narcissistic personality features

2013 ◽  
Vol 54 (2) ◽  
pp. 256-260 ◽  
Author(s):  
Aaron M. Martin ◽  
Eric G. Benotsch ◽  
Shannon Perschbacher Lance ◽  
Marisa Green
Keyword(s):  
Risk Behaviors ◽  
Transmission Risk ◽  
Hiv Positive ◽  
Narcissistic Personality ◽  
Personality Features

scholarly journals The experiences of HIV-positive and HIV-negative children after receiving disclosure of their own and their parents’ illnesses, respectively

2015 ◽  
Author(s):  
Grace Gachanja
Keyword(s):  
Sub Saharan Africa ◽  
Hiv Positive ◽  
Hiv Positive Mothers ◽  
Sub Saharan ◽  
Hiv Negative

The aim of this research brief is to describe a study that sought to understand the post-disclosure experiences of HIV-positive and negative children after they received disclosure of their own and their parents’ illnesses, respectively. This is the first study from Sub-Saharan Africa (SSA) that describes the post-disclosure experiences of HIV-positive and negative children in one study. Prior studies in SSA have mostly centered on the post-disclosure experiences of HIV-positive children after receiving disclosure of their own illnesses, or HIV-positive mothers’ descriptions of the effect of maternal disclosure on their HIV-negative children.

scholarly journals The experiences of HIV-positive and HIV-negative children after receiving disclosure of their own and their parents’ illnesses, respectively

2015 ◽  
Author(s):  
Grace Gachanja
Keyword(s):  
Sub Saharan Africa ◽  
Hiv Positive ◽  
Hiv Positive Mothers ◽  
Sub Saharan ◽  
Hiv Negative

The aim of this research brief is to describe a study that sought to understand the post-disclosure experiences of HIV-positive and negative children after they received disclosure of their own and their parents’ illnesses, respectively. This is the first study from Sub-Saharan Africa (SSA) that describes the post-disclosure experiences of HIV-positive and negative children in one study. Prior studies in SSA have mostly centered on the post-disclosure experiences of HIV-positive children after receiving disclosure of their own illnesses, or HIV-positive mothers’ descriptions of the effect of maternal disclosure on their HIV-negative children.

Sign in / Sign up

Export Citation Format

Share Document