Investigation of heat and mass transfer behavior of mannitol during vial freeze-drying

Author(s):  
M. Muneeshwaran ◽  
G. Srinivasan ◽  
B. Raja ◽  
Chi-Chuan Wang
Symmetry ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 658
Author(s):  
Hao Ma ◽  
Zhipeng Duan

Modeling fluid flows is a general procedure to handle engineering problems. Here we present a systematic study of the flow and heat transfer around a circular cylinder by introducing a new representative appropriate drag coefficient concept. We demonstrate that the new modified drag coefficient may be a preferable dimensionless parameter to describe more appropriately the fluid flow physical behavior. A break in symmetry in the global structure of the entire flow field increases the difficulty of predicting heat and mass transfer behavior. A general simple drag model with high accuracy is further developed over the entire range of Reynolds numbers met in practice. In addition, we observe that there may exist an inherent relation between the drag and heat and mass transfer. A simple analogy model is established to predict heat transfer behavior from the cylinder drag data. This finding provides great insight into the underlying physical mechanism.


2003 ◽  
Vol 21 (2) ◽  
pp. 249-263 ◽  
Author(s):  
Farial Jafar ◽  
Mohammed Farid

1994 ◽  
Vol 116 (1) ◽  
pp. 215-220 ◽  
Author(s):  
Shi-Wen Peng ◽  
Guo-Qian Chen

The present work discusses coupled heat and mass transfer during freeze-drying of a rigid product, as well as accelerated freeze-drying where sublimation and desorption occur concurrently. A desorption mushy zone model was developed to describe the desorption drying. An exact solution was obtained for coupled heat and mass transfer with one discrete sublimation moving interface and one desorption mushy zone where mass transfer is controlled by both Fick and Darcy laws. The effects of several parameters on the sublimation and desorption are analyzed and discussed.


2004 ◽  
Vol 59 (14) ◽  
pp. 2921-2928 ◽  
Author(s):  
Hongwei Wu ◽  
Zhi Tao ◽  
Guohua Chen ◽  
Hongwu Deng ◽  
Guoqiang Xu ◽  
...  

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