scholarly journals Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts

2012 ◽  
Vol 16 (3) ◽  
pp. 613-618 ◽  
Author(s):  
Remigiusz Bąchor ◽  
Marzena Cydzik ◽  
Magdalena Rudowska ◽  
Alicja Kluczyk ◽  
Piotr Stefanowicz ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Quaternary Ammonium ◽  
Electrospray Mass Spectrometry ◽  
Quaternary Ammonium Salts ◽  
Peptide Libraries ◽  
Ammonium Salts ◽  
Mass Spectrometry Analysis ◽  
Spectrometry Analysis

scholarly journals Liquid chromatography–mass spectrometry analysis of dyes formed by in situ oxidative methods then purified by absorption and extraction from hair wefts

2020 ◽  
pp. 174751982097862
Author(s):  
M John Plater ◽  
Andrea Raab
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Complex Mixture ◽  
Ammonium Salts ◽  
Mass Spectrometry Analysis ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Analysis ◽  
Chromatography Mass Spectrometry ◽  
Didecyldimethylammonium Chloride

The dye mixtures formed from three commercial hair colour formers were purified by absorption onto human hair wefts, washed and dried, extracted with dichloromethane:trifluoroacetic acid (75:25) and then analysed by liquid chromatography–mass spectrometry. Only 1–2 dyes were identified from each complex mixture of commercial aromatic amines along with a broad UV absorption mainly consisting of mixtures of quaternary ammonium salts from shampoos and some surfactants. Mecetronium ethyl sulfate and didecyldimethylammonium chloride were the main ammonium salts.

Electrospray mass spectrometry analysis of liquid-phase organic synthesis

1998 ◽  
Vol 4 (1) ◽  
pp. 233 ◽  
Author(s):  
F. Nativel ◽  
C. Enjalbal ◽  
F. Lamaty ◽  
R. Lazaro ◽  
J. Martinez ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Phase ◽  
Organic Synthesis ◽  
Electrospray Mass Spectrometry ◽  
Mass Spectrometry Analysis ◽  
Spectrometry Analysis

Thermal surface ionization of quaternary ammonium salts in particle-beam mass spectrometry

1993 ◽  
Vol 7 (1) ◽  
pp. 37-40 ◽  
Author(s):  
R. A. M. van der Hoeven ◽  
A. P. Tinke ◽  
W. M. A. Niessen ◽  
J. van der Greef
Keyword(s):  
Mass Spectrometry ◽  
Quaternary Ammonium ◽  
Particle Beam ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Surface Ionization

scholarly journals A Non-Covalent Dimer Formation of Quaternary Ammonium Cation with Unusual Charge Neutralization in Electrospray-Ionization Mass Spectrometry

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 5868
Author(s):  
Paulina Grocholska ◽  
Marta Kowalska ◽  
Robert Wieczorek ◽  
Remigiusz Bąchor
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Quaternary Ammonium ◽  
Mass Spectrometry Analysis ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Charge Neutralization ◽  
Spectrometry Analysis ◽  
Covalent Dimer

Specific and nonspecific non-covalent molecular association of biomolecules is characteristic for electrospray-ionization mass spectrometry analysis of biomolecules. Understanding the interaction between two associated molecules is of significance not only from the biological point of view but also gas phase analysis by mass spectrometry. Here we reported a formation of non-covalent dimer of quaternary ammonium denatonium cation with +1 charge detected in the positive ion mode electrospray ionization mass spectrometry analysis of denatonium benzoate. Hydrogen deuterium exchange of amide and carbon-bonded hydrogens revealed that charge neutralization of one denatonium cation is the consequence of amide hydrogen dissociation. DFT (Density Functional Theory) calculations proved high thermodynamic stable of formed dimer stabilized by the short and strong N..H-N hydrogen bond. The signal intensity of the peak characterizing non-covalent dimer is low intensity and does not depend on the sample concentration. Additionally, dimer observation was found to be instrument-dependent. The current investigation is the first experimental and theoretical study on the quaternary ammonium ions dimer. Thus the present study has great significance for understanding the structures of the biomolecules as well as materials.

Sign in / Sign up

Export Citation Format

Share Document