Polymorphism of vascular endothelial growth factor −1154G>A (rs1570360) with cancer risk: a meta-analysis of 16 case–control studies

2011 ◽  
Vol 39 (5) ◽  
pp. 5283-5289 ◽  
Author(s):  
Ting-Ting Hong ◽  
Ru-Xia Zhang ◽  
Xiao-Hong Wu ◽  
Dong Hua
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Case Control ◽  
Vascular Endothelial ◽  
Case Control Studies ◽  
Endothelial Growth Factor

Vascular Endothelial Growth Factor (Vegf) +936 C/T Gene Polymorphisms and Gastric Cancer Risk: A Meta-Analysis Involving 4,138 Subjects

2010 ◽  
Vol 25 (4) ◽  
pp. 213-218 ◽  
Author(s):  
Yong Zhou ◽  
Wen Hu ◽  
Wen Zhuang ◽  
Guan-Jian Liu ◽  
Tai-Xiang Wu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Cancer Risk ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Vascular Endothelial ◽  
Gastric Cancer Risk ◽  
Case Control Studies ◽  
Endothelial Growth Factor

The association between vascular endothelial growth factor (VEGF) +936 C/T gene polymorphisms and gastric cancer risk is still controversial and ambiguous. The objective of our study was to investigate this association. The Medline and Embase databases were searched by two investigators. Crude odds ratios (OR) and 95% confidence intervals (CI) were used to test the association between VEGF +936 C/T polymorphisms and gastric cancer risk. Our meta-analysis comprised seven case-control studies, which included 1,893 gastric cancer cases and 2,245 controls. The combined results showed that there was no relationship between VEGF +936 C/T gene polymorphisms and gastric cancer risk (cc: OR 0.97, 95% CI 0.85, 1.11; CT: OR 1.01, 95% CI 0.88, 1.16; TT: OR 1.10, 95% CI 0.79, 1.55). Subgroup analysis by ethnicity and stage, location, and Lauren classification of gastric cancer did not change the results. This meta-analysis suggests that there is no association between VEGF +936 C/T polymorphisms and gastric cancer risk. Further studies should pay attention to other potentially functional SNPs.

scholarly journals Vascular endothelial growth factor +936C/T polymorphism and gastric cancer risk: A meta-analysis

2011 ◽  
Vol 2 (5) ◽  
pp. 931-936 ◽  
Author(s):  
LI-PING ZHOU ◽  
HONG LUAN ◽  
XIN-HUA DONG ◽  
GUO-JIANG JIN ◽  
DONG-LIANG MAN ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Vascular Endothelial ◽  
Gastric Cancer Risk ◽  
Endothelial Growth Factor

Vascular Endothelial Growth Factor +936C/T and +405G/C Polymorphisms and Cancer Risk: a Meta-analysis

2010 ◽  
Vol 41 (7) ◽  
pp. 548-557 ◽  
Author(s):  
Chao Cao ◽  
Jing-Jing Fang ◽  
Tao Ying ◽  
Shi-Fang Sun ◽  
Dan Lv ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Cancer Risk ◽  
Meta Analysis ◽  
Vascular Endothelial ◽  
Endothelial Growth Factor
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