Transcriptional reprogramming of major defense-signaling pathways during defense priming and sugarcane-Colletotrichum falcatum interaction

2020 ◽  
Vol 47 (11) ◽  
pp. 8911-8923
Author(s):  
N. M. R. Ashwin ◽  
Leonard Barnabas ◽  
Dharmaraj Amalamol ◽  
Kana Valiyaveettil Lakshana ◽  
Amalraj Ramesh Sundar ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Colletotrichum Falcatum ◽  
Defense Signaling ◽  
Defense Priming ◽  
Transcriptional Reprogramming

Volatile compounds from beneficial or pathogenic bacteria differentially regulate root exudation, transcription of iron transporters, and defense signaling pathways in Sorghum bicolor

2018 ◽  
Vol 96 (3) ◽  
pp. 291-304 ◽  
Author(s):  
Erasto Hernández-Calderón ◽  
Maria Elizabeth Aviles-Garcia ◽  
Diana Yazmín Castulo-Rubio ◽  
Lourdes Macías-Rodríguez ◽  
Vicente Montejano Ramírez ◽  
...  
Keyword(s):  
Sorghum Bicolor ◽  
Signaling Pathways ◽  
Volatile Compounds ◽  
Pathogenic Bacteria ◽  
Root Exudation ◽  
Defense Signaling

scholarly journals SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling Pathways

Cancers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 142 ◽  
Author(s):  
Cinzia Bottino ◽  
Alessia Peserico ◽  
Cristiano Simone ◽  
Giuseppina Caretti
Keyword(s):  
Signaling Pathways ◽  
Cancer Progression ◽  
Transcriptional Response ◽  
Migration And Invasion ◽  
Transcriptional Reprogramming ◽  
Oncogenic Pathways ◽  
Tumor Transformation ◽  
Cancer Types ◽  
Oncogenic Driver

SMYD3 is a member of the SMYD lysine methylase family and plays an important role in the methylation of various histone and non-histone targets. Aberrant SMYD3 expression contributes to carcinogenesis and SMYD3 upregulation was proposed as a prognostic marker in various solid cancers. Here we summarize SMYD3-mediated regulatory mechanisms, which are implicated in the pathophysiology of cancer, as drivers of distinct oncogenic pathways. We describe SMYD3-dependent mechanisms affecting cancer progression, highlighting SMYD3 interplay with proteins and RNAs involved in the regulation of cancer cell proliferation, migration and invasion. We also address the effectiveness and mechanisms of action for the currently available SMYD3 inhibitors. The findings analyzed herein demonstrate that a complex network of SMYD3-mediated cytoplasmic and nuclear interactions promote oncogenesis across different cancer types. These evidences depict SMYD3 as a modulator of the transcriptional response and of key signaling pathways, orchestrating multiple oncogenic inputs and ultimately, promoting transcriptional reprogramming and tumor transformation. Further insights into the oncogenic role of SMYD3 and its targeting of different synergistic oncogenic signals may be beneficial for effective cancer treatment.

Nitric oxide regulates multiple defense signaling pathways in peach fruit response to Monilinia fructicola invasion

2020 ◽  
Vol 264 ◽  
pp. 109163
Author(s):  
Guangjin Li ◽  
Zifei Yu ◽  
Jixuan Cao ◽  
Yong Peng ◽  
Jingying Shi
Keyword(s):  
Nitric Oxide ◽  
Signaling Pathways ◽  
Monilinia Fructicola ◽  
Peach Fruit ◽  
Defense Signaling

scholarly journals Resistance to Hemi-Biotrophic F. graminearum Infection Is Associated with Coordinated and Ordered Expression of Diverse Defense Signaling Pathways

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e19008 ◽  
Author(s):  
Lina Ding ◽  
Haibin Xu ◽  
Hongying Yi ◽  
Liming Yang ◽  
Zhongxin Kong ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Defense Signaling

scholarly journals A fatty acid desaturase modulates the activation of defense signaling pathways in plants

2001 ◽  
Vol 98 (16) ◽  
pp. 9448-9453 ◽  
Author(s):  
P. Kachroo ◽  
J. Shanklin ◽  
J. Shah ◽  
E. J. Whittle ◽  
D. F. Klessig
Keyword(s):  
Fatty Acid ◽  
Signaling Pathways ◽  
Fatty Acid Desaturase ◽  
Defense Signaling
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