Six-Year Trend Analysis of Nosocomial Candidemia and Risk factors in Two Intensive Care Hospitals in Mato Grosso, Midwest Region of Brazil

2013 ◽  
Vol 176 (5-6) ◽  
pp. 409-415 ◽  
Author(s):  
Hugo Dias Hoffmann-Santos ◽  
Claudete Rodrigues Paula ◽  
Ana Caroline Akeme Yamamoto ◽  
Tomoko Tadano ◽  
Rosane C. Hahn
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Trend Analysis ◽  
Mato Grosso ◽  
Midwest Region ◽  
Nosocomial Candidemia

scholarly journals KPC: an important mechanism of resistance in K. pneumoniae isolates from intensive care units in the Midwest region of Brazil

2017 ◽  
Vol 11 (08) ◽  
pp. 646-651 ◽  
Author(s):  
Caroline Conci Campos ◽  
Náthalia Franco Roriz ◽  
Camila Nogueira Espínola ◽  
Fernando Aguilar Lopes ◽  
Caroline Tieppo ◽  
...  
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Test Method ◽  
Diffusion Method ◽  
Icu Patients ◽  
Mato Grosso ◽  
Mechanism Of Resistance ◽  
Midwest Region ◽  
Tract Infections ◽  
Mato Grosso Do Sul

Introduction: Infections caused by multidrug-resistant Klebsiella pneumoniae are difficult to treat and pose a serious threat to public health worldwide. Here, we describe the presence of carbapenemase-producing K. pneumoniae in intensive care units (ICU) of three major Mato Grosso do Sul hospitals located in the Midwest region of Brazil. Methodology: A total of 165 K. pneumoniae isolates with reduced susceptibility to carbapenems as identified by the VITEK-2 compact system were studied. Antimicrobial susceptibility testing was performed using the disk diffusion method, as recommended by the Clinical and Laboratory Standards Institute, and the E-test method. The detection of carbapenemase was performed using the modified Hodge test and polymerase chain reaction. Results: The blaKPC gene was identified in 88.1% (n=89) of the selected K. pneumoniae isolates from Beneficent Association of Campo Grande, 94.9% (n=34) of the isolates from the Regional Hospital of Mato Grosso do Sul and 95.2% (n=26) of the isolates from Maria Aparecida Pedrossian University Hospital. Resistance greater than 80% was observed against cephalosporins, aztreonam, ciprofloxacin and piperacillin/tazobactam. Carbapenemase-producing K. pneumoniae (Kp-KPC) isolates were considered important causative agents of urinary tract infections, pneumonia and bloodstream infections in ICU patients. While rarely reported in the literature, we documented three cases of meningoencephalitis caused by Kp-KPC. Conclusions: Our study documents the presence of Kp-KPC in three major Mato Grosso do Sul state hospitals, providing key national epidemiology data. This is an important mechanism of resistance in K. pneumoniae isolates from ICU patients and is associated with resistance to multiple classes of antimicrobial drugs.

Interacting risk factors determine the outcome of patients with a prolonged intensive care unit stay after cardiac surgery

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
J Schöttler ◽  
C Grothusen ◽  
T Attmann ◽  
C Friedrich ◽  
S Freitag-Wolf ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Cardiac Surgery ◽  
Intensive Care ◽  
Intensive Care Unit Stay

Readmission to the Intensive Care Unit after Fast-Track Cardiac Surgery: An Analysis of Risk Factors and Outcome according to the Type of Operation

2010 ◽  
Vol 13 (4) ◽  
pp. E212-E217 ◽  
Author(s):  
Fevzi Toraman ◽  
Sahin Senay ◽  
Umit Gullu ◽  
Hasan Karabulut ◽  
Cem Alhan
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Cardiac Surgery ◽  
Intensive Care ◽  
Fast Track
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