The Role of p53 in the Proliferation and Differentiation of Neural Stem Cells in Organotypic Cultures of Mouse Hippocampus

2015 ◽  
Vol 45 (6) ◽  
pp. 627-636 ◽  
Author(s):  
Yu. S. Grigor’eva ◽  
M. V. Glazova
2013 ◽  
Vol 37 (3) ◽  
pp. 587-592 ◽  
Author(s):  
Jun Ding ◽  
Zhili He ◽  
Juan Ruan ◽  
Zilong Ma ◽  
Ying Liu ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Julieta Aprea ◽  
Federico Calegari

The concerted action of ion channels and pumps establishing a resting membrane potential has been most thoroughly studied in the context of excitable cells, most notably neurons, but emerging evidences indicate that they are also involved in controlling proliferation and differentiation of nonexcitable somatic stem cells. The importance of understanding stem cell contribution to tissue formation during embryonic development, adult homeostasis, and regeneration in disease has prompted many groups to study and manipulate the membrane potential of stem cells in a variety of systems. In this paper we aimed at summarizing the current knowledge on the role of ion channels and pumps in the context of mammalian corticogenesis with particular emphasis on their contribution to the switch of neural stem cells from proliferation to differentiation and generation of more committed progenitors and neurons, whose lineage during brain development has been recently elucidated.


2001 ◽  
Vol 29 (1) ◽  
pp. 1-14
Author(s):  
Stefano F. Pagano ◽  
Sabrina Lucchiari ◽  
Alessandra Bez ◽  
Dario Ponti ◽  
Marco Onofrj ◽  
...  

2015 ◽  
Vol 35 (5) ◽  
Author(s):  
Wei-Zhong Xiao ◽  
An-Qing Lu ◽  
Xin-Wei Liu ◽  
Zhe Li ◽  
Ying Zi ◽  
...  

In the present study, miR-146 promoted spontaneous differentiation of neural stem cells (NSCs), and this mechanism was influenced by miR-146, as well as its target (notch 1) and downstream gene.


2017 ◽  
Vol 31 (7) ◽  
pp. 2839-2853 ◽  
Author(s):  
Sandeep Kumar Agnihotri ◽  
Ruifang Shen ◽  
Jihong Li ◽  
Xu Gao ◽  
Hansruedi Büeler

2021 ◽  
Vol 28 ◽  
Author(s):  
Han Gao ◽  
Ningjing Huang ◽  
Weiwei Wang ◽  
Lingling Zhang ◽  
Li Cai ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document