Modeling of highly sensitive surface plasmon resonance (SPR) sensor for urine glucose detection

In this work, a novel approach to realize a plasmonic sensor is presented. The proposed optical sensor device is designed, manufactured, and experimentally tested. Two photo-curable resins are used to 3D print a surface plasmon resonance (SPR) sensor. Both numerical and experimental analyses are presented in the paper. The numerical and experimental results confirm that the 3D printed SPR sensor presents performances, in term of figure of merit (FOM), very similar to other SPR sensors made using plastic optical fibers (POFs). For the 3D printed sensor, the measured FOM is 13.6 versus 13.4 for the SPR-POF configuration. The cost analysis shows that the 3D printed SPR sensor can be manufactured at low cost (∼15 €) that is competitive with traditional sensors. The approach presented here allows to realize an innovative SPR sensor showing low-cost, 3D-printing manufacturing free design and the feasibility to be integrated with other optical devices on the same plastic planar support, thus opening undisclosed future for the optical sensor systems.

Download Full-text

Black Phosphorus Nanostructure Based Highly Sensitive and Selective Surface Plasmon Resonance Sensor for Biological and Chemical Sensing: A Review

Critical Reviews in Analytical Chemistry ◽

10.1080/10408347.2021.1927669 ◽

2021 ◽

pp. 1-26

Author(s):

Sopan Nangare ◽

Pravin Patil

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Chemical Sensing ◽

Black Phosphorus ◽

Surface Plasmon Resonance Sensor ◽

Highly Sensitive ◽

Resonance Sensor

Download Full-text

An Enhanced Plastic Optical Fiber-Based Surface Plasmon Resonance Sensor with a Double-Sided Polished Structure

Sensors ◽

10.3390/s21041516 ◽

2021 ◽

Vol 21 (4) ◽

pp. 1516

Author(s):

Lian Liu ◽

Shijie Deng ◽

Jie Zheng ◽

Libo Yuan ◽

Hongchang Deng ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Optical Fiber ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Low Cost ◽

Fiber Axis ◽

Plastic Optical Fiber ◽

Au Film ◽

Spr Sensor ◽

Resonance Sensor

An enhanced plastic optical fiber (POF)-based surface plasmon resonance (SPR) sensor is proposed by employing a double-sided polished structure. The sensor is fabricated by polishing two sides of the POF symmetrically along with the fiber axis, and a layer of Au film is deposited on each side of the polished region. The SPR can be excited on both polished surfaces with Au film coating, and the number of light reflections will be increased by using this structure. The simulation and experimental results show that the proposed sensor has an enhanced SPR effect. The visibility and full width at half maximum (FWHM) of spectrum can be improved for the high measured refractive index (RI). A sensitivity of 4284.8 nm/RIU is obtained for the double-sided POF-based SPR sensor when the measured liquid RI is 1.42. The proposed SPR sensor is easy fabrication and low cost, which can provide a larger measurement range and action area to the measured samples, and it has potential application prospects in the oil industry and biochemical sensing fields.

Download Full-text

Surface Plasmon Resonance Based on Molecularly Imprinted Polymeric Film for l-Phenylalanine Detection

Biosensors ◽

10.3390/bios11010021 ◽

2021 ◽

Vol 11 (1) ◽

pp. 21

Author(s):

Duygu Çimen ◽

Nilay Bereli ◽

Adil Denizli

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Limit Of Detection ◽

Kinetic Studies ◽

Force Microscopy ◽

Spr Sensor ◽

Atomic Force ◽

Analysis Technique ◽

Molecular Imprinting Technology

In this study, we designed a simple, rapid, sensitive and selective surface plasmon resonance (SPR) sensor for detection of L-phenylalaine by utilizing molecular imprinting technology. l-phenylalanine imprinted and non-imprinted poly(2-hydroxyethyl methacrylate-methacryloyl-l-phenylalanine) polymeric films were synthesized onto SPR chip surfaces using ultraviolet polymerization. l-phenyalanine imprinted and non-imprinted SPR sensors were characterized by using contact angle, atomic force microscopy and ellipsometry. After characterization studies, kinetic studies were carried out in the concentration range of 5.0–400.0 μM. The limit of detection and quantification were obtained as 0.0085 and 0.0285 μM, respectively. The response time for the test including equilibration, adsorption and desorption was approximately 9 min. The selectivity studies of the l-phenylalanine imprinted SPR sensor was performed in the presence of d-phenylalanine and l-tryptophan. Validation studies were carried out via enzyme-linked immunosorbent analysis technique in order to demonstrate the applicability and superiority of the l-phenylalanine imprinted SPR sensor.

Download Full-text

Cellulose and Vanadium Plasmonic Sensor to Measure Ni2+ Ions

Applied Sciences ◽

10.3390/app11072963 ◽

2021 ◽

Vol 11 (7) ◽

pp. 2963

Author(s):

Nur Alia Sheh Omar ◽

Yap Wing Fen ◽

Irmawati Ramli ◽

Umi Zulaikha Mohd Azmi ◽

Hazwani Suhaila Hashim ◽

...

Keyword(s):

Thin Film ◽

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Signal To Noise Ratio ◽

Affinity Constant ◽

Detection Accuracy ◽

Plasmonic Sensor ◽

Spr Sensor ◽

Resonance Sensor

A novel vanadium–cellulose composite thin film-based on angular interrogation surface plasmon resonance (SPR) sensor for ppb-level detection of Ni(II) ion was developed. Experimental results show that the sensor has a linear response to the Ni(II) ion concentrations in the range of 2–50 ppb with a determination coefficient (R2) of 0.9910. This SPR sensor can attain a maximum sensitivity (0.068° ppb−1), binding affinity constant (1.819 × 106 M−1), detection accuracy (0.3034 degree−1), and signal-to-noise-ratio (0.0276) for Ni(II) ion detection. The optical properties of thin-film targeting Ni(II) ions in different concentrations were obtained by fitting the SPR reflectance curves using the WinSpall program. All in all, the proposed Au/MPA/V–CNCs–CTA thin-film-based surface plasmon resonance sensor exhibits better sensing performance than the previous film-based sensor and demonstrates a wide and promising technology candidate for environmental monitoring applications in the future.

Download Full-text

Highly sensitive surface plasmon resonance immunosensor for parts-per-trillion level detection of 2,4,6-trinitrophenol

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2004.02.010 ◽

2004 ◽

Vol 100 (3) ◽

pp. 450-454 ◽

Cited By ~ 42

Author(s):

D SHANKARAN ◽

K GOBI ◽

K MATSUMOTO ◽

T IMATO ◽

K TOKO ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Highly Sensitive

Download Full-text

Bloch Surface Wave Resonance Based Sensors as an Alternative to Surface Plasmon Resonance Sensors

Sensors ◽

10.3390/s20185119 ◽

2020 ◽

Vol 20 (18) ◽

pp. 5119 ◽

Cited By ~ 1

Author(s):

Michal Gryga ◽

Dalibor Ciprian ◽

Petr Hlubina

Keyword(s):

Surface Plasmon Resonance ◽

Surface Wave ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Moist Air ◽

Polarized Waves ◽

Wave Resonance ◽

Highly Sensitive ◽

Bloch Surface Wave ◽

Spr Effect

We report on a highly sensitive measurement of the relative humidity (RH) of moist air using both the surface plasmon resonance (SPR) and Bloch surface wave resonance (BSWR). Both resonances are resolved in the Kretschmann configuration when the wavelength interrogation method is utilized. The SPR is revealed for a multilayer plasmonic structure of SF10/Cr/Au, while the BSWR is resolved for a multilayer dielectric structure (MDS) comprising four bilayers of TiO2/SiO2 with a rough termination layer of TiO2. The SPR effect is manifested by a dip in the reflectance of a p-polarized wave, and a shift of the dip with the change in the RH, or equivalently with the change in the refractive index of moist air is revealed, giving a sensitivity in a range of 0.042–0.072 nm/%RH. The BSWR effect is manifested by a dip in the reflectance of the spectral interference of s- and p-polarized waves, which represents an effective approach in resolving the resonance with maximum depth. For the MDS under study, the BSWRs were resolved within two band gaps, and for moist air we obtained sensitivities of 0.021–0.038 nm/%RH and 0.046–0.065 nm/%RH, respectively. We also revealed that the SPR based RH measurement is with the figure of merit (FOM) up to 4.7 × 10−4 %RH−1, while BSWR based measurements have FOMs as high as 3.0 × 10−3 %RH−1 and 1.1 × 10−3 %RH−1, respectively. The obtained spectral interferometry based results demonstrate that the BSWR based sensor employing the available MDS has a similar sensitivity as the SPR based sensor, but outperforms it in the FOM. BSW based sensors employing dielectrics thus represent an effective alternative with a number of advantages, including better mechanical and chemical stability than metal films used in SPR sensing.

Download Full-text