Synthesis and Antimicrobial and Antifungal Activity of Carbamate-Functionized Spiro Compounds

2013 ◽  
Vol 46 (12) ◽  
pp. 715-719 ◽  
Author(s):  
A. V. Velikorodov ◽  
V. A. Ionova ◽  
O. V. Degtyarev ◽  
L. T. Sukhenko
Keyword(s):  
Antifungal Activity ◽  
Spiro Compounds ◽  
Antimicrobial And Antifungal Activity

SYNTHESIS AND EVALUATION OF SOME SUBSTITUTED 2-AMINOTHIAZOLE DERIVATIVES FOR THEIR ANTITUBERCULAR, ANTIMICROBIAL & ANTIFUNGAL ACTIVITY

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (01) ◽  
pp. 24-32
Author(s):  
S. R. Pattan ◽  
◽  
S. H Kale ◽  
R. A. Mali ◽  
S. S. Dengale ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Antifungal Agents ◽  
Antitubercular Activity ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Standard Drug ◽  
E Coli ◽  
H Nmr ◽  
Antimicrobial And Antifungal Activity ◽  
Micro Organisms

Millions of people are affected by infectious diseases caused by micro-organisms. Further the widespread microbial resistance had renewed the interest in quest for new antitubercular, antimicrobial & antifungal agents. The present study deals with synthesis & evaluation of some substituted 2-aminothiazole derivatives for their antitubercular, antimicrobial and antifungal activity. 2-aminothiazole derivatives were synthesized by treating substituted acetophenones with thiourea in presence of bromine to give 2-amino 4-substituted phenylthizole and then further treated with chloracetyl chloride to give 2-chloro-N-(4-substituted phenylthizole-2-yl)-acetamide which on refluxing with primary amine gives 15 derivatives. All the synthesized compounds were characterized by IR, H-NMR and elemental analysis.All the synthesized compounds were screened for their antibacterial activity against S. aureus and E. coli by using cup plate agar diffusion method. The activity was measured in terms of zone of inhibition and compared with standard drug ciprofloxacin, sulfonamide. The aminothiazole derivatives were evaluated for antitubercular activity and their result were compared with standard streptomycin.

Synthesis, thermal stability, electronic features, and antimicrobial activity of phenolic azo dyes and their Ni(II) and Cu(II) complexes

2014 ◽  
Vol 68 (3) ◽  
Author(s):  
Selma Bal ◽  
Sedat Bal ◽  
Abdullah Erener ◽  
Hatice Halipci ◽  
Seyhan Akar
Keyword(s):  
Thermal Stability ◽  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Azo Dyes ◽  
Coordination Compounds ◽  
Decomposition Temperature ◽  
Water Soluble ◽  
The Other ◽  
Spectroscopic Methods ◽  
Antimicrobial And Antifungal Activity

AbstractFour water soluble azo dyes, 4-(isopropyl)-2-[(E)-(4-chlorophenyl)diazenyl]phenol (L 1), 4-(isopropyl)-2-[(E)-(2,4-dichlorophenyl)diazenyl]phenol (L2), 4-(sec-butyl)-2-[(E)-(4-chlorophenyl) diazenyl]phenol (L 3), 4-(sec-butyl)-2-[(E)-(2,4-dichlorophenyl)diazenyl]phenol (L 4), and their Cu(II) and Ni(II) complexes were synthesized and characterized using spectroscopic methods. Examination of their thermal stability revealed similar decomposition temperature of approximately 260–300°C and that they were more thermally stable than their metal complexes. Ni(II) complexes of ligands L2 and L4 were more stable than the other coordination compounds. Among the synthesized ligands, L2 and the complexes Cu(L3)2 and Ni(L4)2 showed both antimicrobial and antifungal activity. However, the other ligands and the complexes were poorly active against selected microorganisms.

Preparation and characterization of dispersible chitosan particles with borate crosslinking and their antimicrobial and antifungal activity

2012 ◽  
Vol 349 ◽  
pp. 52-58 ◽  
Author(s):  
Kanako Saita ◽  
Shoji Nagaoka ◽  
Tomohiro Shirosaki ◽  
Maki Horikawa ◽  
Shigeki Matsuda ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Antimicrobial And Antifungal Activity

Synthesis, Antimicrobial and Antifungal Activity of a New Class of Spiro pyrrolidines

2003 ◽  
Vol 11 (3) ◽  
pp. 407-419 ◽  
Author(s):  
A.Amal Raj ◽  
R Raghunathan ◽  
M.R SrideviKumari ◽  
N Raman
Keyword(s):  
Antifungal Activity ◽  
New Class ◽  
Antimicrobial And Antifungal Activity
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