THE STUDY OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF EXTRACTS ORIGANUM VULGARE L.

Author(s):  
K. Zh. Badekova ◽  
M. E. Zholdasbaev ◽  
G.A. Atazhanova ◽  
S. A. Akhmetova ◽  
M. K. Smagulov
2011 ◽  
pp. 165-176 ◽  
Author(s):  
Suncica Kocic-Tanackov ◽  
Gordana Dimic ◽  
Ilija Tanackov ◽  
Danijela Tuco

The paper presents the influence of oregano extract (Origanum vulgare L.) on growth of Aspergillus versicolor, Emericella nidulans, Eurotium herbariorum, E. amstelodami, E. chevalieri and E. rubrum - producers of sterigmatocystin (STC) isolated from salads. Antifungal tests were performed by agar plates method. The composition of the active component of extract was determined by GC-MS method and the major components were: carvacrol (34.20%), triacetin (22.91%), carvone (18.05%), p-cymene (8.05%) and thymol (3.74%). The examined extract showed the ability to reduce mold growth at all applied concentrations. Minimum inhibitory concentrations (MIC) for E. nidulans, E. chevalieri and E. amstelodami were 2.5% (v/v) and over 2.5% (v/v) for A. versicolor. At 1.5% (v/v) concentration the extract completely inhibited the growth of E. rubrum, whereas higher dose of 2.5% (v/v) was fungicidal against E. herbariorum. Besides its sensory role in food products, the examined oregano extract also exhibits antifungal activities against producers of STC.


2021 ◽  
pp. 130506
Author(s):  
Yun Zhao ◽  
Yun-Hai Yang ◽  
Min Ye ◽  
Kai-Bo Wang ◽  
Li-Ming Fan ◽  
...  

2013 ◽  
Vol 46 (12) ◽  
pp. 715-719 ◽  
Author(s):  
A. V. Velikorodov ◽  
V. A. Ionova ◽  
O. V. Degtyarev ◽  
L. T. Sukhenko

2018 ◽  
Vol 49 (4) ◽  
pp. 929-935 ◽  
Author(s):  
Carolina M. Bedoya-Serna ◽  
Gustavo C. Dacanal ◽  
Andrezza M. Fernandes ◽  
Samantha C. Pinho

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (01) ◽  
pp. 24-32
Author(s):  
S. R. Pattan ◽  
◽  
S. H Kale ◽  
R. A. Mali ◽  
S. S. Dengale ◽  
...  

Millions of people are affected by infectious diseases caused by micro-organisms. Further the widespread microbial resistance had renewed the interest in quest for new antitubercular, antimicrobial & antifungal agents. The present study deals with synthesis & evaluation of some substituted 2-aminothiazole derivatives for their antitubercular, antimicrobial and antifungal activity. 2-aminothiazole derivatives were synthesized by treating substituted acetophenones with thiourea in presence of bromine to give 2-amino 4-substituted phenylthizole and then further treated with chloracetyl chloride to give 2-chloro-N-(4-substituted phenylthizole-2-yl)-acetamide which on refluxing with primary amine gives 15 derivatives. All the synthesized compounds were characterized by IR, H-NMR and elemental analysis.All the synthesized compounds were screened for their antibacterial activity against S. aureus and E. coli by using cup plate agar diffusion method. The activity was measured in terms of zone of inhibition and compared with standard drug ciprofloxacin, sulfonamide. The aminothiazole derivatives were evaluated for antitubercular activity and their result were compared with standard streptomycin.


2014 ◽  
Vol 68 (3) ◽  
Author(s):  
Selma Bal ◽  
Sedat Bal ◽  
Abdullah Erener ◽  
Hatice Halipci ◽  
Seyhan Akar

AbstractFour water soluble azo dyes, 4-(isopropyl)-2-[(E)-(4-chlorophenyl)diazenyl]phenol (L 1), 4-(isopropyl)-2-[(E)-(2,4-dichlorophenyl)diazenyl]phenol (L2), 4-(sec-butyl)-2-[(E)-(4-chlorophenyl) diazenyl]phenol (L 3), 4-(sec-butyl)-2-[(E)-(2,4-dichlorophenyl)diazenyl]phenol (L 4), and their Cu(II) and Ni(II) complexes were synthesized and characterized using spectroscopic methods. Examination of their thermal stability revealed similar decomposition temperature of approximately 260–300°C and that they were more thermally stable than their metal complexes. Ni(II) complexes of ligands L2 and L4 were more stable than the other coordination compounds. Among the synthesized ligands, L2 and the complexes Cu(L3)2 and Ni(L4)2 showed both antimicrobial and antifungal activity. However, the other ligands and the complexes were poorly active against selected microorganisms.


2012 ◽  
Vol 349 ◽  
pp. 52-58 ◽  
Author(s):  
Kanako Saita ◽  
Shoji Nagaoka ◽  
Tomohiro Shirosaki ◽  
Maki Horikawa ◽  
Shigeki Matsuda ◽  
...  

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