Microspheres Based on a Protein Matrix and Dipyridamole with Possible Inhalation Administration

2021 ◽  
Author(s):  
A. E. Boldyrev ◽  
M. A. Ziganshin ◽  
N. M. Lyadov ◽  
A. E. Klimovitskii ◽  
A. V. Gerasimov
Keyword(s):  
Protein Matrix ◽  
Inhalation Administration

An Ultra-Structural Study of Human Melanoma in Vivo and Vitro

1976 ◽  
Vol 34 ◽  
pp. 258-259
Author(s):  
James R. Gaylor ◽  
Fredda Schafer ◽  
Robert E. Nordquist
Keyword(s):  
Endoplasmic Reticulum ◽  
Golgi Apparatus ◽  
Protein Aggregation ◽  
Structural Study ◽  
Human Melanoma ◽  
Protein Matrix ◽  
Early Form ◽  
Endoplasmic Reticulum Protein ◽  
Mitochondrial Origin

Several theories on the origin of the melanosome exist. These include the Golgi origin theory, in which a tyrosinase-rich protein is "packaged" by the Golgi apparatus, thus forming the early form of the melanosome. A second theory postulates a mitochondrial origin of melanosomes. Its author contends that the melanosome is a modified mitochondria which acquires melanin during its development. A third theory states that a pre-melanosome is formed in the smooth or rough endoplasmic reticulum. Protein aggregation is suggested by one author as a possible source of the melanosome. This fourth theory postulates that the melanosome originates when the protein products of several genetic loci aggregate in the cytoplasm of the melanocyte. It is this protein matrix on which the melanin is deposited. It was with these theories in mind that this project was undertaken.

Identification of a baculovirus polyhedron formation mutant with a novel phenotype

1996 ◽  
Vol 54 ◽  
pp. 796-797
Author(s):  
James M. Slavicek ◽  
Melissa J. Mercer ◽  
Mary Ellen Kelly
Keyword(s):  
Viral Gene ◽  
Gene Products ◽  
Type Number ◽  
Infection Cycle ◽  
Wild Type ◽  
Protein Matrix ◽  
Insect Midgut ◽  
Viral Particles ◽  
Budded Virus ◽  
Viral Form

Nucleopolyhedroviruses (NPV, family Baculoviridae) produce two morphological forms, a budded virus form and a viral form that is occluded into a paracrystalline protein matrix. This structure is termed a polyhedron and is composed primarily of the protein polyhedrin. Insects are infected by NPVs after ingestion of the polyhedron and release of the occluded virions through dissolution of the polyhedron in the alkaline environment of the insect midgut. Early after infection the budded virus form is produced. It buds through the plasma membrane and then infects other cells. Later in the infection cycle the occluded form of the virus is generated (reviewed by Blissard and Rohrmann, 1990).The processes of polyhedron formation and virion occlusion are likely to involve a number of viral gene products. However, only two genes, the polyhedrin gene and 25K FP gene, have been identified to date that are necessary for the wild type number of polyhedra to be formed and viral particles occluded.

Cereal grain digestion by selected strains of ruminal fungi

1993 ◽  
Vol 39 (4) ◽  
pp. 367-376 ◽  
Author(s):  
T. A. McAllister ◽  
Y. Dong ◽  
L. J. Yanke ◽  
H. D. Bae ◽  
K.-J. Cheng ◽  
...  
Keyword(s):  
Corn Starch ◽  
Fungal Growth ◽  
Wheat Starch ◽  
Cereal Grains ◽  
Starch Granules ◽  
Starch Digestion ◽  
Protein Matrix ◽  
Cereal Grain ◽  
Neocallimastix Patriciarum ◽  
Grain Starch

The ruminal fungi Orpinomyces joyonii strain 19-2, Neocallimastix patriciarum strain 27, and Piromyces communis strain 22 were examined for their ability to digest cereal starch. All strains digested corn starch more readily than barley or wheat starch. Orpinomyces joyonii 19-2 exhibited the greatest propensity to digest starch in wheat and barley, whereas the digestion of these starches by N. patriciarum 27 and P. communis 22 was limited. Media ammonia concentrations were lower when fungal growth was evident, suggesting that all strains assimilate ammonia. Fungi formed extensive rhizoidal systems on the endosperm of corn, but O. joyonii 19-2 was the only strain to form such systems on the endosperm of wheat and barley. All strains penetrated the protein matrix of corn but did not penetrate starch granules. Starch granules from all three cereals were pitted, evidence of extensive digestion by extracellular amylases produced by O. joyonii 19-2. Similar pitting was observed on the surface of corn starch granules digested by N. patriciarum 27 and P. communis 22, but not on wheat and barley starch granules. The ability of ruminal fungi to digest cereal grains depends on both the strain of fungus and the type of grain. The extent to which fungi digest cereal grain in the rumen remains to be determined.Key words: ruminal fungi, cereal grain, starch digestion, ruminant.

Microencapsulation of Propolis in Protein Matrix Using Spray Drying for Application in Food Systems

2018 ◽  
Vol 11 (7) ◽  
pp. 1422-1436 ◽  
Author(s):  
Cristina Jansen-Alves ◽  
Karina F. Fernandes ◽  
Michele M. Crizel-Cardozo ◽  
Fernanda D. Krumreich ◽  
Caroline D. Borges ◽  
...  
Keyword(s):  
Spray Drying ◽  
Food Systems ◽  
Protein Matrix

scholarly journals USE OF FORMALDEHYDE TO REGULATE DIGESTION OF BARLEY STARCH

1990 ◽  
Vol 70 (2) ◽  
pp. 581-589 ◽  
Author(s):  
T. A. McALLISTER ◽  
K.-J. CHENG ◽  
L. M. RODE ◽  
J. G. BUCHANAN-SMITH
Keyword(s):  
Volatile Fatty Acids ◽  
Rumen Bacteria ◽  
Starch Granules ◽  
Endosperm Cell ◽  
Starch Digestion ◽  
Protein Matrix ◽  
Fermentation Efficiency ◽  
Formaldehyde Treatment ◽  
Scanning Electron ◽  
Anaerobic Media

This study was conducted to determine the effect of formaldehyde treatment of barley on the rate of microbial starch digestion. Ground barley was left untreated (UB) or treated with 0.5% formaldehyde (TB) and incubated in vials with an inoculum consisting of a homogenate of rumen contents and Bryant's anaerobic media (1:1). Separate vials were analyzed for starch, ammonia, pH and volatile fatty acids (VFA) after 0, 4, 8, 12, 18, 24, 36 and 48 h. The digestion of starch was lower (P < 0.05) in TB than in UB between 4 and 24 h. Accumulation of NH3 was lower and pH was higher in TB vials (P < 0.05) than in UB vials. VFA production and fermentation efficiency were lower (P < 0.05) in TB than in UB. Formaldehyde treatment of barley reduced (P < 0.05) the production of propionate and enhanced (P < 0.05) the production of butyrate in comparison with UB. Examination by scanning electron microscopy (SEM) showed that the initial colonization of TB was inhibited in comparison with that of UB. The distinct shape of the endosperm cells of TB (12 h) were readily recognizable, but the endosperm cells of UB (12 h) were not readily distinguishable. SEM of TB (24 h) showed that the protein matrix of the endosperm cell is resistant to microbial digestion. The formaldehyde-induced reduction in starch digestion appears to result from the protein matrix inhibiting the access of bacteria to underlying starch granules. Key words: Starch, rumen bacteria, formaldehyde, barley

Permeability and channel structure of reptilian skin

1982 ◽  
Vol 242 (6) ◽  
pp. F681-F689 ◽  
Author(s):  
G. D. Stokes ◽  
W. A. Dunson
Keyword(s):  
Linoleic Acid ◽  
Water Molecule ◽  
Protein Extraction ◽  
Lipid Extraction ◽  
Channel Structure ◽  
Protein Matrix ◽  
Dry Air ◽  
Water Efflux ◽  
Increase Membrane Permeability

A study of the permeability of shed epidermis from some terrestrial and freshwater snakes was conducted. Permeability to Br, Na, and K ions was very low and showed a higher influx than efflux in most cases. Permeability to the smaller water molecule was much greater, and in contrast efflux was higher than influx. Skins from aquatic snakes with larger water permeabilities also showed greater permeabilities to Na and K. The highly aquatic Regina septemvittata has the most permeable skin of any snake. Ethanol fluxes were higher than expected for a tracer of its size, perhaps due to its solubility in lipid. Na fluxes through whole live skins of Nerodia cyclopion floridana in vitro were not significantly different from those of the shed skin alone. Isolated hinge regions showed complete water impermeability, suggesting that channels through the skin are located only in the scale region. Dermal water efflux into dry air was considerably less than water-to-water efflux. Lipid extraction increased permeability markedly and eliminated the asymmetry of water and ion fluxes. Lipid replacement with linoleic acid restored half of the water impermeability lost during extraction. Protein extraction did not significantly increase membrane permeability but did eliminate the permeability difference between dry and hydrated skins. Two sizes of lipid-lined channels extending through a protein matrix are suggested as a possible model for snake skin. The diameter of the channels apparently varies in relation to the differing water, Na, and Cl concentrations on opposite sides of the skin, but the mechanism of this adjustment is unknown.

Preparation and optical properties of silver nanoparticles in R-phycoerythrin, a protein matrix

2008 ◽  
Vol 44 (8) ◽  
pp. 835-841 ◽  
Author(s):  
O. D. Bekasova ◽  
A. A. Brekhovskikh ◽  
A. A. Revina ◽  
V. T. Dubinchuk
Keyword(s):  
Silver Nanoparticles ◽  
Optical Properties ◽  
Protein Matrix
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