Coagulative necrotic pituitary adenoma apoplexy: A retrospective study of 21 cases from a large pituitary center in China

Pituitary ◽  
2018 ◽  
Vol 22 (1) ◽  
pp. 13-28 ◽  
Author(s):  
Zihao Wang ◽  
Lu Gao ◽  
Wenze Wang ◽  
Xiaopeng Guo ◽  
Chenzhe Feng ◽  
...  
2021 ◽  
Author(s):  
Alcubierre Dario De ◽  
Riccardo Pofi ◽  
Emilia Sbardella ◽  
Giulia Puliani ◽  
Valeria Hasenmajer ◽  
...  

2018 ◽  
Vol 118 ◽  
pp. e428-e435 ◽  
Author(s):  
Liang Lv ◽  
Senlin Yin ◽  
Peizhi Zhou ◽  
Yu Hu ◽  
Cheng Chen ◽  
...  

2021 ◽  
Author(s):  
Ilan Shimon ◽  
Zaina Adnan ◽  
Dania Hirsch ◽  
Hadar Duskin-Bitan ◽  
Amit Akirov

Abstract Objective Patients with acromegaly usually present with the classical signs of acromegaly, whereas patients without the specific signs or symptoms are rarely diagnosed. This unique entity can be named "subclinical acromegaly". Methods This was a retrospective study. Our study group consisted of 8 patients (6 females) with incidentally diagnosed acromegaly, most following head MRI for unrelated reasons and without the specific signs of acromegaly. Results Mean age at diagnosis was 50.1 ± 16.3 years. Baseline IGF-1 ranged between 1.27–2.08 x upper limit of normal (ULN). MRI depicted a pituitary microadenoma in 6 patients, one patient presented with an intrasellar macroadenoma and one had no visible pituitary mass. Mean calculated SAGIT clinical score was 4.6. Three patients underwent trans-sphenoidal resection; two achieved hormonal remission and one improved but did not normalize IGF-1 following surgery. Five patients (including one following surgery) were given somatostatin analogs, and three normalized IGF-1. Several patients improved clinically following treatment, reporting improvement in snoring, hypertension, or weight loss, and pituitary adenoma decreased in size in 2 patients that responded to medical treatment. Conclusions we report a series of 8 patients with very mild and subclinical acromegaly. It is uncertain whether all such patients will gain clinical benefit from treatment, but some experienced clinical improvement due to treatment.


F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 430
Author(s):  
Abbas Ali Mansour ◽  
Ali Hussain Ali Alhamza ◽  
Ammar Mohammed Saeed Abdullah Almomin ◽  
Ibrahim Abbood Zaboon ◽  
Nassar Taha Yaseen Alibrahim ◽  
...  

Background: Pituitary disorders spectrum includes a wide variety of diseases.This study aimed at a comprehensive description of such disorders for patients from  Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah (Southern Iraq). Methods: Retrospective data analysis of FDEMC for the period from January 2012 through June 2017. We included all patients with pituitary disorders who have MRI pituitary. Results: The pituitary disorders were more common among women. Those with macroadenoma were older than those with microadenoma with nearly equal gender prevalence of macroadenoma. Pituitary adenoma constituted the bulk of pituitary disorders in this registry (67.2%). Growth hormone secreting adenoma were the commonest adenoma seen in 41.0% followed by clinically non-functioning pituitary adenoma(NFPA)in 31.4% and prolactinoma in 26.9%. About 64.8% of pituitary adenoma was macroadenoma. Macroadenoma was seen in 73.4 % of growth hormone secreting adenoma, 61.2% in NFPA and 62.0% of prolactinoma (of them six were giant prolactinoma) Conclusion: Pituitary adenoma constituted the bulk of pituitary disorders in Basrah, growth hormone secreting adenoma is the commonest adenoma followed by NFPA and prolactinoma due to referral bias. A change  in  practice of pituitary adenoma treatment is needed.


2017 ◽  
Vol 41 ◽  
pp. 62-67 ◽  
Author(s):  
Pedro Iglesias ◽  
Karina Arcano ◽  
Vanessa Triviño ◽  
Paula García-Sancho ◽  
Juan José Díez ◽  
...  

1996 ◽  
Vol 6 (1) ◽  
pp. 69-73 ◽  
Author(s):  
S. Milazzo ◽  
P. Toussaint ◽  
F. Proust ◽  
G. Touzet ◽  
D. Malthieu

Pituitary apoplexy is an acute hemorragic or ischemic infarction in pituitary adenomas. The incidence in our series was 6.5%. Clinical diagnosis can often be difficult as the patient is frequently unaware of an existing adenoma (seven out of 11 patients). Therefore, the classic features of the syndrome must be known. They include sudden headaches, impairment of consciousness, endocrinological disturbances and sudden visual deterioration or oculomotor palsies. In this retrospective study from 1987 to 1994 of 14 patients presenting pituitary apoplexy there were 11 cases with visual abnormalities. Oculomotor palsies were more common (82%) than chiasmatic impairment (54.5%) and often revealed pituitary adenoma. CT-Scan and MRI examinations led to diagnosis, and emergency treatment (surgical removal by rhinoseptal approach or less often medical treatment) generally led to a regression of visual disturbances.


Author(s):  
Eva Horvath ◽  
Kalman Kovacs ◽  
B. W. Scheithauer ◽  
R. V. Lloyd ◽  
H. S. Smyth

The association of a pituitary adenoma with nervous tissue consisting of neuron-like cells and neuropil is a rare abnormality. In the majority of cases, the pituitary tumor is a chromophobic adenoma, accompanied by acromegaly. Histology reveals widely variable proportions of endocrine and nervous tissue in alternating or intermingled patterns. The lesion is perceived as a composite one consisting of two histogenetically distinct parts. It has been suggested that the neuronal component, morphologically similar to secretory neurons of the hypothalamus, may initiate adenoma formation by releasing stimulatory substances. Immunoreactivity for growth hormone releasing hormone (GRH) in the neuronal component of some cases supported this view, whereas other findings such as consistent lack of growth hormone (GH) cell hyperplasia in the lesions called for alternative explanation.Fifteen tumors consisting of a pituitary adenoma and a neuronal component have been collected over a 20 yr. period. Acromegaly was present in 11 patients, was equivocal in one, and absent in 3.


2020 ◽  
Vol 47 (6) ◽  
pp. 855.e3
Author(s):  
C. Cannarozzo ◽  
P. Kirch ◽  
L. Campoy ◽  
R. Gleed ◽  
M. Martin-Flores
Keyword(s):  

Ob Gyn News ◽  
2005 ◽  
Vol 40 (8) ◽  
pp. 6
Author(s):  
Christine Kilgore
Keyword(s):  

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