Statistical methodology is crucial in prognostic factor analysis of health-related quality of life

2008 ◽  
Vol 17 (7) ◽  
pp. 1043-1044 ◽  
Author(s):  
M. E. Mauer ◽  
A. Bottomley ◽  
C. Coens
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Prognostic Factor ◽  
Health Related Quality ◽  
Statistical Methodology ◽  
Related Quality ◽  
Health Related

scholarly journals Comment on “Health-related quality of life as a prognostic factor of survival in critically ill patients”

2009 ◽  
Vol 35 (7) ◽  
pp. 1308-1308
Author(s):  
Dominique M. Vandijck ◽  
Sandra G. Oeyen ◽  
Lieven Annemans ◽  
Johan M. Decruyenaere
Keyword(s):  
Quality Of Life ◽  
Prognostic Factor ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Development, initial validation and reliability testing of a web-based, generic feline health-related quality-of-life instrument

2018 ◽  
Vol 21 (2) ◽  
pp. 84-94 ◽  
Author(s):  
Cory E Noble ◽  
Lesley M Wiseman-Orr ◽  
Marian E Scott ◽  
Andrea M Nolan ◽  
Jacky Reid
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Correlation Coefficients ◽  
Health Related Quality ◽  
Web Based ◽  
Scoring Algorithm ◽  
Related Quality ◽  
Health Related ◽  
Test Retest Reliability

Objectives The objective of this study was to develop a valid, reliable, web-based generic feline health-related quality-of-life (HRQoL) questionnaire instrument to measure the affective impact of chronic disease. Methods A large initial item pool, obtained through interviews with cat owners, was reduced using predetermined criteria, survey scores for relevance and clarity, and the ability of individual items to discriminate between healthy and sick cats when owners completed a prototype questionnaire. Using these data, factor analysis was used to derive a scoring algorithm and provide evidence for factorial validity. Validity was demonstrated further in a field trial using a ‘known groups’ approach (sick vs healthy cats will have a different HRQoL profile, and the HRQoL profile of cats will deteriorate as comorbidities increase). Test–retest reliability was assessed using intra-class correlation coefficients (ICCs). Results In total, 165 items were reduced to 20 and, on the basis of a factor analysis that explained 72.3% of the variation in scores input by 71 owners of 30 healthy and 41 sick cats using the prototype, these were allocated to three domains (vitality, comfort and emotional wellbeing [EWB]) with a scoring algorithm derived using item loadings. Subsequently, the owners of 36 healthy and 58 sick cats completed one or two (n = 48) assessments. Median scores (healthy vs sick) for all domains were significantly different ( P <0.001), 78% of cats were correctly classified as healthy or sick and for comorbidities the correlation coefficients were moderate (vitality 0.64; comfort 0.63; EWB 0.50). Test–retest reliability was good (ICC vitality 0.635; comfort 0.716; EWB 0.853). Conclusions and relevance This study provides initial evidence for the validity and reliability of a novel HRQoL instrument to aid the assessment and management of chronic diseases of cats.

scholarly journals Validation of a Spanish version of the Health-Related Quality of Life (HRQoL) measure for Chronic Otitis Media (COMQ-12)

2020 ◽  
Author(s):  
Ana M. Otoya Tono ◽  
Lucía C. Pérez Herrera ◽  
Daniel Peñaranda García ◽  
Sergio Moreno López ◽  
Ricardo Sánchez Pedraza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Otitis Media ◽  
Internal Consistency ◽  
Chronic Otitis Media ◽  
Spanish Version ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background Evaluation of health-related quality of life (HRQoL) is considered an important aspect of clinical assessment and health research. Chronic Otitis Media (COM) is related to the quality of life deterioration subsequent to COM symptoms, social communication impairments and lower work performance. However, there is no reliable information regarding the impact of this disease on health and quality of life in many resource-poor countries. Therefore, we translated into Spanish and culturally adapted the Chronic Otitis Media Questionnaire-12 (COMQ-12) for the evaluation of Health-Related Quality of Life (HRQoL) of Chronic Otitis Media (COM) in adult patients. Also, we assessed the psychometric properties of our version of the questionnaire.Methods Two otology referral centers in Bogotá, Colombia were included. The Spanish version of COMQ-12 was applied twice to 200 adult patients with confirmed COM diagnosis and to 31 healthy controls in order to perform the validation process and assess the internal consistency of this questionnaire. Psychometric characteristics (replicability, reliability, and validity) of the COMQ-12 were assessed. Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were conducted via structural equation modeling (SEM) in order to test the questionnaire’s structure.Results The Spanish version of the COMQ-12 showed good internal consistency (Cronbach’s Alpha=0.8526, McDonald’s Omega = 0.8901). Coefficients corresponding to Lin’s Concordance test and test-retest reliability were 0.945 and 0.82 respectively. Correlation between the Visual Analogue Scale (VAS) and the COMQ-12 was = 0.676 (IC 95% = 0.593; 0.745). Factor analysis of the Spanish version of the COMQ-12 indicated a questionnaire structure with three domains: smelly discharge related symptoms; hearing loss related symptoms; and impact on work, lifestyle and health services.Conclusion This Spanish version of the COMQ-12 showed high reliability and high internal consistency. This questionnaire can be used as an objective clinical tool to assess the HRQoL of patients who have a COM diagnosis.

scholarly journals Validation of a SPANISH version of the Health-Related Quality of Life (HRQoL) measure for Chronic Otitis Media (COMQ-12)

2020 ◽  
Author(s):  
Ana M. Otoya-Tono ◽  
Lucía C. Pérez-Herrera ◽  
Daniel Peñaranda ◽  
Sergio Moreno-López ◽  
Ricardo Sánchez-Pedraza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Factor Analysis ◽  
Otitis Media ◽  
Internal Consistency ◽  
Chronic Otitis Media ◽  
Spanish Version ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background: Evaluation of health-related quality of life (HRQoL) is considered an important aspect of clinical assessment and health research. Chronic Otitis Media (COM) is related to the quality of life deterioration subsequent to COM symptoms, social communication impairments, and lower work performance. However, there is no reliable information regarding the impact of this disease on health and quality of life in many resource-poor countries. Therefore, we translated into Spanish and culturally adapted the Chronic Otitis Media Questionnaire-12 (COMQ-12) for the evaluation of HRQoL of Chronic Otitis Media (COM) in adult patients. Also, we assessed the psychometric properties of the Spanish version of the questionnaire. Methods: Two otology referral centers in Bogotá, Colombia were included. The Spanish version of COMQ-12 was applied twice to 200 adult patients with confirmed COM diagnosis and 31 healthy controls to perform the validation process and assess the internal consistency of this questionnaire. Psychometric characteristics (internal consistency, test-retest reliability, and construct validity) of the COMQ-12 were assessed. Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were conducted via structural equation modeling (SEM) to test the questionnaire’s structure. Results: The Spanish version of the COMQ-12 showed good internal consistency (Cronbach’s Alpha: 0.852, McDonald’s Omega: 0.890). Coefficients corresponding to Lin’s Concordance test and test-retest reliability were 0.945 and 0.825 respectively. Correlation between the Visual Analogue Scale (VAS) and the COMQ-12 was 0.676 (95% CI: 0.593; 0.745) . Factor analysis of the Spanish version of the COMQ-12 indicated a questionnaire structure with three domains: smelly discharge related symptoms; hearing loss related symptoms; and impact on work, lifestyle, and health services . Conclusion: This Spanish version of the COMQ-12 showed high reliability and high internal consistency. This questionnaire can be used as an objective clinical tool to assess the HRQoL of patients who have a COM diagnosis. Trial registration Not applicable. Key Words: Chronic Suppurative Otitis Media, Health-Related Quality of Life, COMQ-12, validity.

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