Distribution, source, and environmental risk assessment of phthalate esters (PAEs) in water, suspended particulate matter, and sediment of a typical Yangtze River Delta City, China

2019 ◽  
Vol 26 (24) ◽  
pp. 24609-24619 ◽  
Author(s):  
Hui Chen ◽  
Wei Mao ◽  
Yiqiu Shen ◽  
Weiwei Feng ◽  
Guanghua Mao ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Particulate Matter ◽  
Suspended Particulate Matter ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Yangtze River ◽  
Phthalate Esters ◽  
Yangtze River Delta ◽  
River Delta ◽  
Suspended Particulate

scholarly journals Exposure Assessment of Multiple Mycotoxins and Cumulative Health Risk Assessment: A Biomonitoring-Based Study in the Yangtze River Delta, China

Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 103
Author(s):  
Qingwen Huang ◽  
Keqiu Jiang ◽  
Zhanmin Tang ◽  
Kai Fan ◽  
Jiajia Meng ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Yangtze River ◽  
Yangtze River Delta ◽  
River Delta ◽  
Urine Samples ◽  
Health Concern ◽  
Cumulative Exposure ◽  
The Yangtze River ◽  
Two Samples ◽  
The Yangtze River Delta

The extensive exposure to multiple mycotoxins has been demonstrated in many countries; however, realistic assessments of the risks related to cumulative exposure are limited. This biomonitoring study was conducted to investigate exposure to 23 mycotoxins/metabolites and their determinants in 227 adults (aged 20–88 years) in the Yangtze River Delta, China. Eight mycotoxins were detected in 110 urine samples, and multiple mycotoxins co-occurred in 51/227 (22.47%) of urine samples, with deoxynivalenol (DON), fumonisin B1 (FB1), and zearalenone (ZEN) being the most frequently occurring. For single mycotoxin risk assessment, FB1, ZEN, aflatoxin B1 (AFB1), and ochratoxin A (OTA) all showed potential adverse effects. However, for the 12 samples containing DON and ZEN, in which none had a hazard risk, the combination of both mycotoxins in two samples was considered to pose potential endocrine disrupting risks to humans by hazard index (HI) method. The combined margin of exposure (MOET) for AFB1 and FB1 could constitute a potential health concern, and AFB1 was the main contributor. Our approach provides a blueprint for evaluating the cumulative risks related to different types of mycotoxins and opens a new horizon for the accurate interpretation of epidemiological health outcomes related to multi-mycotoxin exposure.

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