Genome sequencing brought Gossypium biology research into a new era

2017 ◽  
Vol 60 (12) ◽  
pp. 1463-1466 ◽  
Author(s):  
Fuguang Li ◽  
Zuoren Yang ◽  
Zhi Wang ◽  
Zhao’en Yang
Keyword(s):  
Genome Sequencing ◽  
New Era ◽  
Biology Research

The emergence of inter-clade hybrid SARS-CoV-2 lineages revealed by 2D nucleotide variation mapping

2020 ◽  
Author(s):  
Hai-Long Wang
Keyword(s):  
Big Data ◽  
Genome Sequencing ◽  
High Throughput ◽  
Mayo Clinic ◽  
High Throughput Sequencing ◽  
Genetic Recombination ◽  
Whole Genome ◽  
Nucleotide Variation ◽  
Genome Sequences ◽  
New Era

ABSTRACTI performed whole-genome sequencing on SARS-CoV-2 collected from COVID-19 samples at Mayo Clinic Rochester in mid-April, 2020, generated 85 consensus genome sequences and compared them to other genome sequences collected worldwide. I proposed a novel illustrating method using a 2D map to display populations of co-occurring nucleotide variants for intra- and inter-viral clades. This method is highly advantageous for the new era of “big-data” when high-throughput sequencing is becoming readily available. Using this method, I revealed the emergence of inter-clade hybrid SARS-CoV-2 lineages that are potentially caused by homologous genetic recombination.

scholarly journals Phage display – a tool for detection and prevention against pathogens. A review

2021 ◽  
Vol 8 (1) ◽  
pp. 23-33
Author(s):  
Barbora Vidová ◽  
Andrej Godány ◽  
Ernest Šturdík
Keyword(s):  
Nucleotide Sequence ◽  
Phage Display ◽  
Genome Sequencing ◽  
Treatment Strategies ◽  
Microbial Pathogens ◽  
Molecular Technique ◽  
Bacterial Detection ◽  
Foreign Proteins ◽  
Sequence Encoding ◽  
Biology Research

In this article are reviewed the promising uses of phage display in the areas such as microbial pathogens detection of and vaccination. Phage display is a molecular technique by which foreign proteins are expressed at the surface of phage particles. Such phages thereby become vehicles for expression that not only carry within them the nucleotide sequence encoding expressed proteins, but have also the capability to replicate. Recent data acquired from genome sequencing and advances in phage biology research have aided the development of phage-derived bacterial detection and treatment strategies.

Sign in / Sign up

Export Citation Format

Share Document