scholarly journals A mathematical method for quantifying in vivo mechanical behaviour of heel pad under dynamic load

2015 ◽  
Vol 54 (2-3) ◽  
pp. 341-350 ◽  
Author(s):  
Roozbeh Naemi ◽  
Panagiotis E. Chatzistergos ◽  
Nachiappan Chockalingam
2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S649-S649
Author(s):  
Laurent Besret ◽  
Jean-Dominique Gallezot ◽  
Frédéric Dollé ◽  
Philippe Hantraye ◽  
Marie-Claude Grégoire

2012 ◽  
Vol 34 (9) ◽  
pp. 1253-1259 ◽  
Author(s):  
C.G. Fontanella ◽  
S. Matteoli ◽  
E.L. Carniel ◽  
J.E. Wilhjelm ◽  
A. Virga ◽  
...  

2021 ◽  
Vol 22 (23) ◽  
pp. 12928
Author(s):  
Constança Júnior ◽  
Maria Narciso ◽  
Esther Marhuenda ◽  
Isaac Almendros ◽  
Ramon Farré ◽  
...  

Pulmonary fibrosis (PF) is a progressive disease that disrupts the mechanical homeostasis of the lung extracellular matrix (ECM). These effects are particularly relevant in the lung context, given the dynamic nature of cyclic stretch that the ECM is continuously subjected to during breathing. This work uses an in vivo model of pulmonary fibrosis to characterize the macro- and micromechanical properties of lung ECM subjected to stretch. To that aim, we have compared the micromechanical properties of fibrotic ECM in baseline and under stretch conditions, using a novel combination of Atomic Force Microscopy (AFM) and a stretchable membrane-based chip. At the macroscale, fibrotic ECM displayed strain-hardening, with a stiffness one order of magnitude higher than its healthy counterpart. Conversely, at the microscale, we found a switch in the stretch-induced mechanical behaviour of the lung ECM from strain-hardening at physiological ECM stiffnesses to strain-softening at fibrotic ECM stiffnesses. Similarly, we observed solidification of healthy ECM versus fluidization of fibrotic ECM in response to stretch. Our results suggest that the mechanical behaviour of fibrotic ECM under stretch involves a potential built-in mechanotransduction mechanism that may slow down the progression of PF by steering resident fibroblasts away from a pro-fibrotic profile.


Foot & Ankle ◽  
1989 ◽  
Vol 9 (6) ◽  
pp. 294-299 ◽  
Author(s):  
Uffe Jørgensen ◽  
Finn Bojsen-Møller

The heel pad acts as a shock absorber in walking and in heel-strike running. In some patients, a reduction of its shock-absorbing capacity has been connected to the development of overuse injuries. In this article, the shock absorption of the heel pad as well as external shock absorbers are studied. Individual variation and the effect of trauma and confinement on the heel pad were specifically investigated. Drop tests, imitating heel impacts, were performed on a force plate. The test specimens were cadaver heel pads (n = 10); the shoe sole component consisted of ethyl vinyl acetate (EVA) foam and Sorbothane inserts. The shock absorption was significantly greater in the heel pad than in the external shock absorbers. The mean heel pad shock absorption was 1.1 times for EVA foam and 2.1 times for Sorbothane. The shock absorption varied by as much as 100% between heel pads. Trauma caused a decrease in the heel pad shock absorbency (24%), whereas heel pad confinement increased the shock absorbency (49% in traumatized heel pads and 29.5% in nontraumatized heel pads). These findings provide a biomechanical rationale for the clinical observations of a correlation between heel pad shock absorbency loss and heel strike-dependent overuse injuries. To increase shock absorbency, confinement of the heel pad should be attempted in vivo.


Author(s):  
Pavana Sirimamilla ◽  
Ahmet Erdemir ◽  
Antonie J. van den Bogert ◽  
Jason P. Halloran

Experimental testing of cadaver specimens is a useful means to quantify structural and material response of tissue and passive joint properties against applied loading[1,4]. Very often, specific material response (i.e., stress-strain behavior of a ligament or plantar tissue) has been the goal of experimental testing and is accomplished with uniaxial and/or biaxial tests of prepared tissue specimens with uniform geometries[2,5]. Material properties can then be calculated directly and if testing data involves individual sets of multiple loading modes (e.g. compression only, shear only, volumetric) an accurate representation of the global response of the specimen may be possible. In foot biomechanics, however, it is practically impossible to perform isolated mechanical testing in this manner. The structural response, therefore the stiffness characteristics, of the foot have been quantified, usually using a dominant loading mode: e.g., whole foot compression [6], heel pad indentation [3]. This approach ignores the complexity of most in vivo loading conditions, in which whole foot deformation involves interactions between compression, shear (e.g. heel pad) and tension (e.g. ligaments). Therefore, the purpose of this study was to quantify the mechanical response of a cadaver foot specimen subjected to compression and anterior-posterior (AP) shear loading of isolated heel and forefoot regions as well as whole foot compression. Results from the experimental tests represent a novel methodology to quantify a complete structural biomechanical response. Combined with medical imaging, followed by inverse finite element (FE) analysis, the data may also serve for material characterization of foot tissue.


2001 ◽  
Vol 34 (12) ◽  
pp. 1661-1665 ◽  
Author(s):  
Amit Gefen ◽  
Michal Megido-Ravid ◽  
Yacov Itzchak

2008 ◽  
Vol 40 (Supplement) ◽  
pp. S81
Author(s):  
Adam L. Bryant ◽  
Ross A. Clark ◽  
Simon Bartold ◽  
Aron Murphy ◽  
Erik Hohmann ◽  
...  

2006 ◽  
Vol 179 (1) ◽  
pp. 152-163 ◽  
Author(s):  
Refaat E. Gabr ◽  
Ronald Ouwerkerk ◽  
Paul A. Bottomley
Keyword(s):  

1993 ◽  
Vol 14 (06) ◽  
pp. 312-319 ◽  
Author(s):  
H. Kinoshita ◽  
T. Ogawa ◽  
K. Kuzuhara ◽  
K. Ikuta
Keyword(s):  

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