scholarly journals Relationship of Racial Residential Segregation to Newly Diagnosed Cases of HIV among Black Heterosexuals in US Metropolitan Areas, 2008–2015

2018 ◽  
Vol 96 (6) ◽  
pp. 856-867 ◽  
Author(s):  
Umedjon Ibragimov ◽  
Stephanie Beane ◽  
Adaora A. Adimora ◽  
Samuel R. Friedman ◽  
Leslie Williams ◽  
...  
Keyword(s):  
Residential Segregation ◽  
Metropolitan Areas ◽  
Newly Diagnosed ◽  
Racial Residential Segregation ◽  
Relationship Of

scholarly journals Racial residential segregation and economic disparity jointly exacerbate the COVID-19 fatality in large American cities

2020 ◽  
Author(s):  
Qinggang Yu ◽  
Cristina Salvador ◽  
Irene Melani ◽  
Martha Berg ◽  
Enrique Neblett ◽  
...  
Keyword(s):  
Income Inequality ◽  
Residential Segregation ◽  
Urban Areas ◽  
Metropolitan Areas ◽  
Policy Implications ◽  
Current Evidence ◽  
Structural Inequality ◽  
Racial Residential Segregation ◽  
Economic Disparity ◽  
The U.S

The disproportionately high rates of both infections and deaths of underprivileged racial minorities in the U.S. (including Blacks and Hispanics) during the current COVID-19 pandemic show that structural inequality can be lethal. However, the nature of this structural inequality is poorly understood. Here, we hypothesized that two structural features of urban areas in the U.S. (racial residential segregation and income inequality) contribute to numerous health-compromising conditions, which, in turn, exacerbate COVID-19 fatalities. These two features may be particularly lethal when combined. To test this hypothesis, we examined the growth rate of both confirmed COVID-19 cases and deaths in an early 30-day period of the outbreak in the counties located in each of the 100 largest metropolitan areas in the U.S. The growth curve for cases and deaths was steeper in counties located in metropolitan areas that residentially segregate Blacks and Hispanics. Moreover, this effect of racial residential segregation was augmented by income inequality within each county. The current evidence highlights the role of racial and economic disparity in producing the devastating human toll in the current pandemic. It also offers important policy implications for making virus-resilient cities.

scholarly journals Neighborhood Opportunities, Race, and Class: The Black Middle Class and Residential Segregation

2004 ◽  
Vol 3 (1) ◽  
pp. 43-63 ◽  
Author(s):  
Robert M. Adelman
Keyword(s):  
Middle Class ◽  
Residential Segregation ◽  
College Graduates ◽  
Census Data ◽  
Metropolitan Areas ◽  
Social Scientists ◽  
Racial Residential Segregation ◽  
Race And Class ◽  
Female Headed Households ◽  
Middle Class Blacks

Racial residential segregation has received considerable attention from social scientists who, in general, have found that African Americans, particularly those in large, northeastern and midwestern metropolitan areas have been highly segregated from whites since at least the beginning of the Great Migration. This analysis combines research on racial residential segregation with research about residential segregation based on social class in order to study the segregation of middle‐class blacks from middle‐class whites. By using Census data that incorporate consistent geographic definitions of Census tracts in 50 U.S. metropolitan areas from 1970 to 1990, I assess change in the levels of residential segregation between middle‐class blacks and middle‐class whites. The index of dissimilarity indicates that while there was a decrease in the segregation of middle‐class blacks from middle‐class whites between 1970 and 1990, in many metropolitan areas this segregation remained high through 1990. The analysis also shows that middle‐class blacks lived in neighborhoods, on average, with considerably more poverty, more boarded‐up homes, more female‐headed households, and fewer college graduates than neighborhoods inhabited by middle‐class whites. Overall, the results suggest that, for the most part, these groups remain residentially separated in U.S. metropolitan areas.

scholarly journals Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Kylee H. Maclachlan ◽  
Even H. Rustad ◽  
Andriy Derkach ◽  
Binbin Zheng-Lin ◽  
Venkata Yellapantula ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Copy Number ◽  
Prognostic Impact ◽  
Newly Diagnosed ◽  
Flexible Tool ◽  
Whole Exome ◽  
Hematological Cancers ◽  
Relationship Of ◽  
The Relationship ◽  
Validation Series

AbstractChromothripsis is detectable in 20–30% of newly diagnosed multiple myeloma (NDMM) patients and is emerging as a new independent adverse prognostic factor. In this study we interrogate 752 NDMM patients using whole genome sequencing (WGS) to investigate the relationship of copy number (CN) signatures to chromothripsis and show they are highly associated. CN signatures are highly predictive of the presence of chromothripsis (AUC = 0.90) and can be used identify its adverse prognostic impact. The ability of CN signatures to predict the presence of chromothripsis is confirmed in a validation series of WGS comprised of 235 hematological cancers (AUC = 0.97) and an independent series of 34 NDMM (AUC = 0.87). We show that CN signatures can also be derived from whole exome data (WES) and using 677 cases from the same series of NDMM, we are able to predict both the presence of chromothripsis (AUC = 0.82) and its adverse prognostic impact. CN signatures constitute a flexible tool to identify the presence of chromothripsis and is applicable to WES and WGS data.

scholarly journals The Effect of Racial Residential Segregation on Black Infant Mortality

2008 ◽  
Vol 168 (11) ◽  
pp. 1247-1254 ◽  
Author(s):  
M. O. Hearst ◽  
J. M. Oakes ◽  
P. J. Johnson
Keyword(s):  
Infant Mortality ◽  
Residential Segregation ◽  
Racial Residential Segregation ◽  
Black Infant

Residential Segregation and Ethnic Enterprise in U.S. Metropolitan Areas

2000 ◽  
Vol 47 (3) ◽  
pp. 408-424 ◽  
Author(s):  
Mary J. Fischer ◽  
Douglas S. Massey
Keyword(s):  
Residential Segregation ◽  
Metropolitan Areas
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